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GPR17 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS246757

MBS246757 is an antibody targeting GPR17. Also known as Rabbit Polyclonal to Human GPR17. Reactive in Gibbon, Gorilla, Human. Host: Rabbit. GPR17 is an Orphan-A GPCR with an unknown ligand. More details

$630 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
GPR17, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal to Human GPR17
Product Gene Name
Product Synonym Names
Anti-GPR17 Antibody (N-Terminus) IHC-plus; GPR17; G protein-coupled receptor 17; G-protein coupled receptor 17; p2Y-like receptor; Y12546; Z94155; R12; UDP/CysLT receptor; Human GPR17
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Gibbon, Gorilla, Human
Form/Format
PBS, 0.1% sodium azide.
Purity/Purification
Immunoaffinity Purified
Concentration
1 mg/ml (lot specific)
Specificity
Human GPR17. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Preparation and Storage
Long term: -70 degree C; Short term: +4 degree C
Molecular Weight
37,827 Da
OMIM
603071
3D Structure
ModBase 3D Structure for Q13304
Target Species
Human
Immunogen Description
Synthetic 16 amino acid peptide from N-terminal extracellular domain of human GPR17. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon (100%).
Immunogen Type
Synthetic peptide
Immunogen
GPR17 antibody was raised against synthetic 16 amino acid peptide from N-terminal extracellular domain of human GPR17. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon (100%).
Antigen Modification
N-Terminus
Applications Tested/Suitable for anti-GPR17 antibody
Immunohistochemistry (IHC - Paraffin), Immunocytochemistry (ICC)
Application Notes for anti-GPR17 antibody
ICC (3 - 16 ug/ml), IHC-P (3 ug/ml)

Immunohistochemistry (IHC) of anti-GPR17 antibody

Anti-GPR17 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Rabbit Anti-GPR17 Polyclonal Antibody – Cat# MBS246757

Immunohistochemistry (IHC) of anti-GPR17 antibody

Anti-GPR17 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Rabbit Anti-GPR17 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS246757

Transfection of anti-GPR17 antibody

Anti-GPR17 antibody immunocytochemistry (ICC) staining of HEK293 human embryonic kidney cells transfected with GPR17.
Rabbit Anti-GPR17 Polyclonal Antibody, Transfection – Cat# MBS246757

Transfection Control of anti-GPR17 antibody

Anti-GPR17 antibody immunocytochemistry (ICC) staining of untransfected HEK293 human embryonic kidney cells.
Rabbit Anti-GPR17 Polyclonal Antibody, Transfection Control – Cat# MBS246757

Other Notes

Small volumes of anti-GPR17 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for GPR17. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
uracil nucleotide/cysteinyl leukotriene receptor isoform a
NCBI Official Synonym Full Names
G protein-coupled receptor 17
NCBI Official Symbol
GPR17
UniProt Protein Name
Uracil nucleotide/cysteinyl leukotriene receptor
UniProt Synonym Protein Names
G-protein coupled receptor 17; P2Y-like receptor; R12
UniProt Gene Name
GPR17
UniProt Synonym Gene Names
UDP/CysLT receptor
UniProt Entry Name
GPR17_HUMAN
NCBI Protein Information
uracil nucleotide/cysteinyl leukotriene receptor; R12; P2Y-like receptor; UDP/CysLT receptor; G-protein coupled receptor 17

UniProt Comments for GPR17

GPR17: Dual specificity receptor for uracil nucleotides and cysteinyl leukotrienes (CysLTs). Signals through G(i) and inhibition of adenylyl cyclase. May mediate brain damage by nucleotides and CysLTs following ischemia. Belongs to the G-protein coupled receptor 1 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, multi-pass; GPCR, family 1; Membrane protein, integral; Receptor, GPCR

Chromosomal Location of Human Ortholog: 2q21

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: chemokine receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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