Rabbit Anti-MAPK15 Polyclonal Antibody – Cat# MBS246789

Anti-MAPK15 antibody IHC of human lung. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.

MAPK15 Antibody – Rabbit Polyclonal

Name: MAPK15 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS246789
Price: 625 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS246789

ERK8 is a MAPK type protein kinase that is activated by a Src-dependent signaling pathway. The protein contains two SH3-binding motifs in its C-terminal region and has been shown to associate with the c-Src SH3 domain in vitro and co-immunoprecipitate with… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

MAPK15 / ERK7, Polyclonal Antibody

Full Product Name

Rabbit Polyclonal (IgG) to Human MAPK15 / ERK7

Product Gene Name

anti-MAPK15 antibody

Product Synonym Gene Name

ERK7

Product Synonym Names

Anti-MAPK15 / ERK7 Antibody (aa361-410) IHC-plus; MAPK15; ERK7; ERK-8; MAPK 15; MAP kinase 15; ERK-7; ERK8; Human MAPK15; ERK7

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol

Purity/Purification

Immunoaffinity Purified

Concentration

1 mg/ml (lot specific)

Specificity

MAPK15 Antibody detects endogenous levels of total MAPK15 protein.

Preparation and Storage

Store at -20 degree C for up to one year.

Molecular Weight

31,112 Da

3D Structure

ModBase 3D Structure for Q8TD08

Target Species

Human

Immunogen Description

Synthetic peptide from human MAPK15 (aa361-410).

Immunogen

MAPK15 / ERK7 antibody was raised against synthetic peptide from human MAPK15 (aa361-410).

Antigen Modification

aa361-410

Product Categories/Family for anti-MAPK15 antibody

Family: Protein Kinase; Subfamily: MAPK

Applications Tested/Suitable for anti-MAPK15 antibody

Immunohistochemistry (IHC - Paraffin), ELISA (EIA)

Application Notes for anti-MAPK15 antibody

ELISA (1:5000), IHC-P (10 ug/ml)

Other Notes

Small volumes of anti-MAPK15 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MAPK15 purchase

MBS246789 is an antibody targeting MAPK15. Also known as Rabbit Polyclonal (IgG) to Human MAPK15 / ERK7. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for MAPK15. It may not necessarily be applicable to this product.

NCBI GI #

95147356

NCBI GeneID

225689

NCBI Accession #

NP_620590.2

UniProt Primary Accession #

Q8TD08

UniProt Secondary Accession #

Q2TCF9; Q8N362

UniProt Related Accession #

Q8TD08

GenBank Nucleotide #

NM_139021.2

NCBI Official Full Name

mitogen-activated protein kinase 15

NCBI Official Synonym Full Names

mitogen-activated protein kinase 15

NCBI Official Symbol

MAPK15

NCBI Official Synonym Symbols

ERK7; ERK8

UniProt Protein Name

Mitogen-activated protein kinase 15

UniProt Synonym Protein Names

Extracellular signal-regulated kinase 7; ERK-7; Extracellular signal-regulated kinase 8; ERK-8

UniProt Gene Name

MAPK15

UniProt Synonym Gene Names

ERK7; ERK8; MAP kinase 15; MAPK 15; ERK-7; ERK-8

UniProt Entry Name

MK15_HUMAN

NCBI Protein Information

mitogen-activated protein kinase 15; ERK-7; ERK-8; MAPK 15; MAP kinase 15; extracellular regulated kinase 8 delta; extracellular signal regulated kinase 8; extracellular signal-regulated kinase 7; extracellular signal-regulated kinase 8

UniProt Comments for MAPK15

ERK7: In vitro, phosphorylates MBP. Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Kinase, protein; Protein kinase, Ser/Thr (non-receptor); Protein kinase, CMGC; EC 2.7.11.24; CMGC group; MAPK family; Erk7 subfamily

Chromosomal Location of Human Ortholog: -

Cellular Component: extracellular region; intracellular; nucleus

Molecular Function: MAP kinase activity; SH3 domain binding; ATP binding

Biological Process: positive regulation of protein ubiquitination; negative regulation of DNA replication; protein amino acid autophosphorylation; positive regulation of protein catabolic process; MAPKKK cascade; positive regulation of protein amino acid phosphorylation; negative regulation of transcription from RNA polymerase II promoter; response to estradiol stimulus

Research Articles on MAPK15

1. Data suggest that the model coulb be a tool for the development of specific ERK8 kinase inhibitors.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.