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ESYT1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS246852

ESYT1 (formerly FAM62A) belongs to a family of membranous calcium sensor proteins that contain multiple C2 domains. The C2 domains are involved in calcium binding and are found in proteins that function in membrane traffic and/or signal transduction. More details

$650 / 0.05 mg +1 FREE 8GB USB
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
ESYT1, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal to Human ESYT1
Product Gene Name
Product Synonym Names
Anti-ESYT1 Antibody (C-Terminus) IHC-plus; ESYT1; E-Syt1; Extended synaptotagmin-1; KIAA0747; MBC2; FAM62A; Human ESYT1
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Predicted Reactivity: Orangutan, Gibbon, Monkey (at least 90% immunogen sequence identity)
Form/Format
PBS, 0.1% sodium azide.
Purity/Purification
Immunoaffinity Purified
Concentration
1 mg/ml (lot specific)
Specificity
Human ESYT1 / FAM62A. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Preparation and Storage
Long term: -70 degree C; Short term: +4 degree C
Molecular Weight
124,003 Da
3D Structure
ModBase 3D Structure for Q9BSJ8
Target Species
Human
Immunogen Description
Synthetic 16 amino acid peptide from C-terminus of human ESYT1 / FAM62A. Percent identity with other species by BLAST analysis: Human (100%); Orangutan, Gibbon, Monkey (94%); Marmoset (88%); Bovine, Dog, Horse, Pig (81%).
Immunogen Type
Synthetic peptide
Immunogen
ESYT1 antibody was raised against synthetic 16 amino acid peptide from C-terminus of human ESYT1 / FAM62A. Percent identity with other species by BLAST analysis: Human (100%); Orangutan, Gibbon, Monkey (94%); Marmoset (88%); Bovine, Dog, Horse, Pig (81%).
Antigen Modification
C-Terminus
Applications Tested/Suitable for anti-ESYT1 antibody
Immunohistochemistry (IHC - Paraffin)
Application Notes for anti-ESYT1 antibody
IHC-P (10 - 12.5 ug/ml)

Immunohistochemistry (IHC) of anti-ESYT1 antibody

Anti-ESYT1 / FAM62A antibody IHC of human thyroid. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Rabbit Anti-ESYT1 Polyclonal Antibody – Cat# MBS246852

Immunohistochemistry (IHC) of anti-ESYT1 antibody

Anti-ESYT1 / FAM62A antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Rabbit Anti-ESYT1 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS246852

Other Notes

Small volumes of anti-ESYT1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ESYT1 purchase

MBS246852 is an antibody targeting ESYT1. Also known as Rabbit Polyclonal to Human ESYT1. Reactive in Human
Predicted Reactivity: Orangutan, Gibbon, Monkey (at least 90% immunogen sequence identity). Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for ESYT1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
extended synaptotagmin-1 isoform 2
NCBI Official Synonym Full Names
extended synaptotagmin-like protein 1
NCBI Official Symbol
ESYT1
NCBI Official Synonym Symbols
MBC2; FAM62A
UniProt Protein Name
Extended synaptotagmin-1
UniProt Synonym Protein Names
Membrane-bound C2 domain-containing protein
UniProt Gene Name
ESYT1
UniProt Synonym Gene Names
FAM62A; KIAA0747; MBC2; E-Syt1
UniProt Entry Name
ESYT1_HUMAN
NCBI Protein Information
extended synaptotagmin-1; membrane-bound C2 domain-containing protein; family with sequence similarity 62 (C2 domain containing), member A

UniProt Comments for ESYT1

ESYT1: May play a role as calcium-regulated intrinsic membrane protein. Belongs to the extended synaptotagmin family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 12q13.2

Cellular Component: membrane; plasma membrane; integral to endoplasmic reticulum membrane

Molecular Function: protein binding; metal ion binding; phospholipid binding

Biological Process: lipid transport
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with anti-ESYT1 antibody

 Organ/Tissue Name  Pubmed Publications
 Eye Antibodies  >1 publications with ESYT1 and Eye
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