Goat Anti-UBP1 Polyclonal Antibody – Cat# MBS246861

Anti-UBP1 antibody IHC of human adrenal medulla. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.

UBP1 Antibody – Goat Polyclonal

Name: UBP1 Antibody; Polyclonal; Goat; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS246861
Price: 625 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS246861

MBS246861 is an antibody targeting UBP1. Also known as Goat Polyclonal to Human UBP1. Reactive in HumanPredicted Reactivity: Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey (at least 90% immunogen sequence identity). Host: Goat. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

UBP1, Polyclonal Antibody

Full Product Name

Goat Polyclonal to Human UBP1

Product Gene Name

anti-UBP1 antibody

Product Synonym Names

Anti-UBP1 Antibody (Internal) IHC-plus; UBP1; LBP1; LBP-1a; LBP1A; LBP1B; Transcription factor LBP-1; Upstream-binding protein 1; LBP-1B; Human UBP1

Clonality

Polyclonal

Host

Goat

Species Reactivity

Human
Predicted Reactivity: Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey (at least 90% immunogen sequence identity)

Form/Format

Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide

Purity/Purification

Immunoaffinity Purified

Concentration

0.5 mg/ml (lot specific)

Specificity

Human UBP1. Reported variants represent identical protein: NP_001121633.1, NP_055332.3.

Preparation and Storage

Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles.

Molecular Weight

56,453 Da

OMIM

609784

3D Structure

ModBase 3D Structure for Q9NZI7

Target Species

Human

Immunogen Description

Synthetic peptide C-PNHQGDGASQTSGE from an internal region of human UBP1 (NP_055332.3; NP_001121632.1). Percent identity with other species by BLAST analysis: Human (100%), Chimpanzee (93%), Gorilla (93%), Orangutan (93%), Gibbon (93%), Monkey (93%).

Immunogen Type

Synthetic peptide

Immunogen

UBP1 antibody was raised against synthetic peptide C-PNHQGDGASQTSGE from an internal region of human UBP1 (NP_055332.3; NP_001121632.1). Percent identity with other species by BLAST analysis: Human (100%), Chimpanzee (93%), Gorilla (93%), Orangutan (93%), Gibbon (93%), Monkey (93%), Marmoset (86%), Mouse (86%), Rabbit (86%).

Antigen Modification

Internal

Applications Tested/Suitable for anti-UBP1 antibody

Immunohistochemistry (IHC - Paraffin), ELISA (EIA)

Application Notes for anti-UBP1 antibody

ELISA (1:2000), IHC-P (10 ug/ml)
Usage: Peptide ELISA: antibody detection limit dilution 1:2000. Western blot: Preliminary experiments in Human Kidney, Human Adrenal gland, HeLa and HepG2 lysates gave no specific signal but low background (at antibody concentration up to 2 ug/ml).

Other Notes

Small volumes of anti-UBP1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for UBP1. It may not necessarily be applicable to this product.

NCBI GI #

189491630

NCBI GeneID

7342

NCBI Accession #

NP_055332.3

UniProt Primary Accession #

Q9NZI7

UniProt Secondary Accession #

Q68CT0; Q86Y57; Q9H8V0; Q9UD76; Q9UD78

UniProt Related Accession #

Q9NZI7

GenBank Nucleotide #

NM_014517.4

NCBI Official Full Name

upstream-binding protein 1 isoform LBP-1b

NCBI Official Synonym Full Names

upstream binding protein 1 (LBP-1a)

NCBI Official Symbol

UBP1

NCBI Official Synonym Symbols

LBP1A; LBP1B; LBP-1B; LBP-1a

UniProt Protein Name

Upstream-binding protein 1

UniProt Synonym Protein Names

Transcription factor LBP-1

Protein Family

Oligouridylate-binding protein

UniProt Gene Name

UBP1

UniProt Synonym Gene Names

LBP1

UniProt Entry Name

UBIP1_HUMAN

NCBI Protein Information

upstream-binding protein 1; transcription factor LBP-1

UniProt Comments for UBP1

UBP1: Functions as a transcriptional activator in a promoter context-dependent manner. Modulates the placental expression of CYP11A1. Involved in regulation of the alpha-globin gene in erythroid cells. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with TFCP2. Involved in regulation of the alpha-globin gene in erythroid cells. Binds strongly to sequences around the HIV-1 initiation site and weakly over the TATA-box. Represses HIV-1 transcription by inhibiting the binding of TFIID to the TATA-box. Belongs to the grh/CP2 family. CP2 subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 3p22.3

Cellular Component: nucleoplasm; cytoplasm; nucleus

Molecular Function: DNA binding; sequence-specific DNA binding; transcription factor activity; transcription corepressor activity

Biological Process: regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent; viral genome replication; angiogenesis; negative regulation of transcription, DNA-dependent

Research Articles on UBP1

1. Data revealed that dimers composed of LBP-1a and LBP-1c were re-formed probably by a partner-exchange of LBP-1b-containing heterodimers.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-UBP1 antibody

Reference Product	PubMed Publications
TFCP2L1 antibody	>4 publications with UBP1 and TFCP2L1
YY1 antibody	>2 publications with UBP1 and YY1
DPYD antibody	>1 publications with UBP1 and DPYD

Diseases associated with anti-UBP1 antibody

Disease Name	Pubmed Publications
Fetal Growth Retardation Antibodies	>1 publications with UBP1 and Fetal Growth Retardation
Fetal Death Antibodies	>1 publications with UBP1 and Fetal Death
Necrosis Antibodies	>1 publications with UBP1 and Necrosis

Organs/Tissues associated with anti-UBP1 antibody

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>4 publications with UBP1 and Blood
Placenta Antibodies	>4 publications with UBP1 and Placenta
Embryonic Tissue Antibodies	>3 publications with UBP1 and Embryonic Tissue
Bone Marrow Antibodies	>2 publications with UBP1 and Bone Marrow
Lung Antibodies	>2 publications with UBP1 and Lung
Bone Antibodies	>2 publications with UBP1 and Bone
Connective Tissue Antibodies	>1 publications with UBP1 and Connective Tissue
Liver Antibodies	>1 publications with UBP1 and Liver
Skin Antibodies	>1 publications with UBP1 and Skin
Kidney Antibodies	>1 publications with UBP1 and Kidney