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TREX2 Antibody – Goat Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS246911

MBS246911 is an antibody targeting TREX2. Also known as Goat Polyclonal to Human TREX2. Reactive in HumanPredicted Reactivity: Monkey (at least 90% immunogen sequence identity). Host: Goat. More details

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Product Overview

Product Name
TREX2, Polyclonal Antibody
Full Product Name
Goat Polyclonal to Human TREX2
Product Gene Name
Product Synonym Names
Anti-TREX2 Antibody (Internal) IHC-plus; TREX2; 3-5 exonuclease TREX2; Human TREX2
Clonality
Polyclonal
Host
Goat
Species Reactivity
Human
Predicted Reactivity: Monkey (at least 90% immunogen sequence identity)
Form/Format
Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Purity/Purification
Immunoaffinity Purified
Concentration
0.5 mg/ml (lot specific)
Specificity
Human TREX2.
Preparation and Storage
Store at -20 degree C. Minimize freezing and thawing.
Molecular Weight
25,955 Da
3D Structure
ModBase 3D Structure for Q9R1A9
Target Species
Human
Immunogen Description
Synthetic peptide C-HRSSLENPEHDES from an internal region of human TREX2 (NP_542432.2). Percent identity with other species by BLAST analysis: Human (100%), Marmoset (92%), Gibbon (85%), Monkey (85%), Mouse (85%), Rat (85%), Hamster (85%).
Immunogen Type
Synthetic peptide
Immunogen
TREX2 antibody was raised against synthetic peptide C-HRSSLENPEHDES from an internal region of human TREX2 (NP_542432.2). Percent identity with other species by BLAST analysis: Human (100%), Marmoset (92%), Gibbon (85%), Monkey (85%), Mouse (85%), Rat (85%), Hamster (85%), Panda (85%), Dog (85%), Horse (85%).
Antigen Modification
Internal
Applications Tested/Suitable for anti-TREX2 antibody
Immunohistochemistry (IHC - Paraffin), ELISA (EIA)
Application Notes for anti-TREX2 antibody
ELISA (1:128000), IHC-P (3.75 ug/ml)
Usage: Peptide ELISA: antibody detection limit dilution 1:128000. Western blot: Preliminary experiments gave an approx 18kDa band in lysates of Jurkat, MOLT4 and U937 after 0.5 ug/ml antibody staining. Please note that currently we cannot find an explanatio...

Immunohistochemistry (IHC) of anti-TREX2 antibody

Anti-TREX2 antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml.
Goat Anti-TREX2 Polyclonal Antibody – Cat# MBS246911

Other Notes

Small volumes of anti-TREX2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for TREX2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
three prime repair exonuclease 2
NCBI Official Synonym Full Names
three prime repair exonuclease 2
NCBI Official Symbol
Trex2
UniProt Protein Name
Three prime repair exonuclease 2
UniProt Synonym Protein Names
3'-5' exonuclease TREX2
UniProt Gene Name
Trex2
UniProt Entry Name
TREX2_MOUSE
NCBI Protein Information
three prime repair exonuclease 2; 3'-5' exonuclease TREX2

UniProt Comments for TREX2

TREX2: Exonuclease with a preference for double stranded DNA with mismatched 3' termini. May play a role in DNA repair. Belongs to the exonuclease superfamily. TREX family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Deoxyribonuclease; EC 3.1.11.2; DNA repair, damage

Cellular Component: nucleus

Molecular Function: nuclease activity; protein homodimerization activity; nucleic acid binding; hydrolase activity; metal ion binding; exonuclease activity; magnesium ion binding; 3'-5'-exodeoxyribonuclease activity; exodeoxyribonuclease III activity

Biological Process: DNA repair; DNA catabolic process, exonucleolytic; DNA metabolic process; response to DNA damage stimulus
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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