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QSOX2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS246961

MBS246961 is an antibody targeting QSOX2. Also known as Rabbit Polyclonal to Human QSOX2. Reactive in Gorilla, Human. Host: Rabbit. More details

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Sample Manual Insert View PDF
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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
QSOX2, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal to Human QSOX2
Product Gene Name
Product Synonym Names
Anti-QSOX2 Antibody (C-Terminus) IHC-plus; QSOX2; Quiescin Q6-like protein 1; SOXN; Sulfhydryl oxidase 2; QSCN6L1; Quiescin Q6-like 1; Human QSOX2
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Gorilla, Human
Form/Format
PBS, 0.1% sodium azide.
Purity/Purification
Immunoaffinity Purified
Concentration
0.75 mg/ml (lot specific)
Specificity
Human QSOX2. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Preparation and Storage
Long term: -70 degree C; Short term: +4 degree C
Molecular Weight
77,529 Da
OMIM
612860
3D Structure
ModBase 3D Structure for Q6ZRP7
Target Species
Human
Immunogen Description
Synthetic 20 amino acid peptide from C-Terminus of human QSOX2. Percent identity with other species by BLAST analysis: Human, Gorilla (100%).
Immunogen Type
Synthetic peptide
Immunogen
QSOX2 antibody was raised against synthetic 20 amino acid peptide from C-Terminus of human QSOX2. Percent identity with other species by BLAST analysis: Human, Gorilla (100%).
Antigen Modification
C-Terminus
Applications Tested/Suitable for anti-QSOX2 antibody
Immunohistochemistry (IHC - Paraffin)
Application Notes for anti-QSOX2 antibody
IHC-P (10 ug/ml)

Immunohistochemistry (IHC) of anti-QSOX2 antibody

Anti-QSOX2 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Rabbit Anti-QSOX2 Polyclonal Antibody – Cat# MBS246961

Immunohistochemistry (IHC) of anti-QSOX2 antibody

Anti-QSOX2 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Rabbit Anti-QSOX2 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS246961

Other Notes

Small volumes of anti-QSOX2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for QSOX2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
sulfhydryl oxidase 2
NCBI Official Synonym Full Names
quiescin Q6 sulfhydryl oxidase 2
NCBI Official Symbol
QSOX2
NCBI Official Synonym Symbols
SOXN; QSCN6L1
UniProt Protein Name
Sulfhydryl oxidase 2
UniProt Synonym Protein Names
Neuroblastoma-derived sulfhydryl oxidase; Quiescin Q6-like protein 1
Protein Family
UniProt Gene Name
QSOX2
UniProt Synonym Gene Names
QSCN6L1; SOXN
UniProt Entry Name
QSOX2_HUMAN
NCBI Protein Information
sulfhydryl oxidase 2; quiescin Q6-like 1; quiescin Q6-like protein 1; neuroblastoma-derived sulfhydryl oxidase

NCBI Summary for QSOX2

QSOX2 is a member of the sulfhydryl oxidase/quiescin-6 (Q6) family (QSOX1; MIM 603120) that regulates the sensitization of neuroblastoma cells for IFN-gamma (IFNG; MIM 147570)-induced cell death (Wittke et al., 2003 [PubMed 14633699]).[supplied by OMIM, Jun 2009]

UniProt Comments for QSOX2

QSCN6L1: Catalyzes the oxidation of sulfhydryl groups in peptide and protein thiols to disulfides with the reduction of oxygen to hydrogen peroxide. May contribute to disulfide bond formation in a variety of secreted proteins. Also seems to play a role in regulating the sensitization of neuroblastoma cells for interferon-gamma-induced apoptosis. Belongs to the quiescin-sulfhydryl oxidase (QSOX) family.

Protein type: Oxidoreductase; Apoptosis; Membrane protein, integral; EC 1.8.3.2

Chromosomal Location of Human Ortholog: 9q34.3

Cellular Component: nuclear membrane; extracellular region; plasma membrane; integral to membrane

Molecular Function: thiol oxidase activity

Biological Process: cell redox homeostasis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-QSOX2 antibody

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