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FRMPD4 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS246970

MBS246970 is an antibody targeting FRMPD4. Also known as Rabbit Polyclonal to Human FRMPD4. Reactive in Human. Host: Rabbit. More details

$750 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
FRMPD4, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal to Human FRMPD4
Product Gene Name
Product Synonym Names
Anti-FRMPD4 Antibody (Internal) IHC-plus; FRMPD4; KIAA0316; PDZD10; PDZK10; Preso; PDZ domain containing 10; Human FRMPD4
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
PBS, 0.02% sodium azide
Purity/Purification
Immunoaffinity Purified
Concentration
1 mg/ml (lot specific)
Specificity
Human FRMPD4
Preparation and Storage
Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles. Store undiluted.
Molecular Weight
144,379 Da
OMIM
300838
3D Structure
ModBase 3D Structure for Q14CM0
Target Species
Human
Immunogen Description
An 18 amino acid peptide from near the center of human FRMPD4.
Immunogen Type
Synthetic peptide
Immunogen
FRMPD4 antibody was raised against an 18 amino acid peptide from near the center of human FRMPD4.
Antigen Modification
Internal
Applications Tested/Suitable for anti-FRMPD4 antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)
Application Notes for anti-FRMPD4 antibody
ELISA, IHC-P (5 ug/ml), WB (1 - 2 ug/ml)
Usage: FRMPD4 antibody can be used for detection of FRMPD4 by Western blot at 1-2 ug/ml.

Immunohistochemistry (IHC) of anti-FRMPD4 antibody

Anti-FRMPD4 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Rabbit Anti-FRMPD4 Polyclonal Antibody – Cat# MBS246970

Immunofluorescence (IF) of anti-FRMPD4 antibody

Immunofluorescence of FRMPD4 in human brain tissue with FRMPD4 antibody at 20 ug/ml.
Rabbit Anti-FRMPD4 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS246970

Western Blot (WB) of anti-FRMPD4 antibody

Western blot of FRMPD4 in SK-N-SH cell lysate with FRMPD4 antibody at (A) 1 and (B) 2 ug/ml.
Rabbit Anti-FRMPD4 Polyclonal Antibody, Western Blot (WB) – Cat# MBS246970

Other Notes

Small volumes of anti-FRMPD4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for FRMPD4. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
FERM and PDZ domain-containing protein 4
NCBI Official Synonym Full Names
FERM and PDZ domain containing 4
NCBI Official Symbol
FRMPD4
NCBI Official Synonym Symbols
PDZD10; PDZK10
UniProt Protein Name
FERM and PDZ domain-containing protein 4
UniProt Synonym Protein Names
PDZ domain-containing protein 10; PSD-95-interacting regulator of spine morphogenesis; Preso
UniProt Gene Name
FRMPD4
UniProt Synonym Gene Names
KIAA0316; PDZD10; PDZK10; Preso
UniProt Entry Name
FRPD4_HUMAN
NCBI Protein Information
FERM and PDZ domain-containing protein 4; Preso; PDZ domain-containing protein 10; PSD-95-interacting FERM and PDZ domain protein; PSD-95-interacting regulator of spine morphogenesis

NCBI Summary for FRMPD4

This gene encodes a multi-domain (WW, PDZ, FERM) containing protein. Through its interaction with other proteins (such as PSD-95), it functions as a positive regulator of dendritic spine morphogenesis and density, and is required for the maintenance of excitatory synaptic transmission. [provided by RefSeq, Jan 2010]
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UniProt Comments for FRMPD4

FRMPD4: Positive regulator of dendritic spine morphogenesis and density. Required for the maintenance of excitatory synaptic transmission. Binds phosphatidylinositol 4,5-bisphosphate.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: Xp22.2

Cellular Component: cytoskeleton; dendritic spine

Molecular Function: protein binding; phosphatidylinositol-4,5-bisphosphate binding

Biological Process: positive regulation of synapse structural plasticity
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with anti-FRMPD4 antibody

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