SLC25A6 Antibody – Rabbit Polyclonal

This gene is a member of the mitochondrial carrier subfamily of solute carrier protein genes. The product of this gene functions as a gated pore that translocates ADP from the cytoplasm into the mitochondrial matrix and ATP from the mitochondrial matrix into the cytoplasm. The protein is implicated in the function of the permability transition pore complex (PTPC), which regulates the release of mitochondrial products that induce apoptosis. The human genome contains several non-transcribed pseudogenes of this gene. [provided by RefSeq, Jun 2013]

SLC25A6: Catalyzes the exchange of cytoplasmic ADP with mitochondrial ATP across the mitochondrial inner membrane. May participate in the formation of the permeability transition pore complex (PTPC) responsible for the release of mitochondrial products that triggers apoptosis. Belongs to the mitochondrial carrier family.

Protein type: Mitochondrial; Transporter, SLC family; Transporter; Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: Xp22.32 and Yp11.3

Cellular Component: mitochondrion; mitochondrial inner membrane; integral to membrane; nucleus; mitochondrial inner membrane presequence translocase complex

Molecular Function: protein binding; ATP:ADP antiporter activity

Biological Process: ATP transport; ADP transport; cellular protein metabolic process; viral reproduction; apoptosis; virus-host interaction; active induction of host immune response by virus; energy reserve metabolic process; viral infectious cycle; regulation of insulin secretion; protein targeting to mitochondrion; transmembrane transport