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LIN41 Antibody – Goat Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS246998

MBS246998 is an antibody targeting LIN41. Also known as Goat Polyclonal to Human LIN41 / TRIM71. Reactive in Bat, Gibbon, Bovine, Chicken, Dog, Gorilla, Horse, Human, Monkey, Rabbit, Rat, ZebrafishPredicted Reactivity: Mouse, Xenopus (at least 90% immunogen… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
LIN41 / TRIM71, Polyclonal Antibody
Full Product Name
Goat Polyclonal to Human LIN41 / TRIM71
Product Gene Name
Product Synonym Gene Name
TRIM71
Product Synonym Names
Anti-LIN41 / TRIM71 Antibody (Internal) IHC-plus; TRIM71; Abnormal cell LINeage LIN-41; Homolog of C. elegans Lin-41; Protein lin-41 homolog; LIN41; Tripartite motif containing 71; Tripartite motif-containing 71; LIN-41; Human LIN41; TRIM71
Clonality
Polyclonal
Host
Goat
Species Reactivity
Bat, Gibbon, Bovine, Chicken, Dog, Gorilla, Horse, Human, Monkey, Rabbit, Rat, Zebrafish
Predicted Reactivity: Mouse, Xenopus (at least 90% immunogen sequence identity)
Form/Format
Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Purity/Purification
Immunoaffinity Purified
Concentration
0.5 mg/ml (lot specific)
Specificity
Human TRIM71.
Preparation and Storage
Store at -20 degree C. Minimize freezing and thawing.
Molecular Weight
93,385 Da
3D Structure
ModBase 3D Structure for Q2Q1W2
Target Species
Human
Immunogen Description
Synthetic peptide C-RQVKAKSLYLQVE from an internal region of human TRIM71 (NP_001034200.1).
Immunogen Type
Synthetic peptide
Immunogen
LIN41 / TRIM71 antibody was raised against synthetic peptide C-RQVKAKSLYLQVE from an internal region of human TRIM71 (NP_001034200.1). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Rat, Elephant, Panda, Bovine, Dog, Bat, Horse, Rabbit, Opossum, Turkey, Chicken, Platypus, Lizard, Pufferfish, Zebrafish (100%); Mouse, Xenopus, Stickleback (92%).
Antigen Modification
Internal
Applications Tested/Suitable for anti-LIN41 antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)
Application Notes for anti-LIN41 antibody
ELISA (1:8000), IHC-P (3.75 ug/ml), WB (0.5 - 1 ug/ml)
Usage: Peptide ELISA: antibody detection limit dilution 1:8000. Western blot: Approx 100kDa band observed in lysates of the cell lines HEK293 and NIH3T3 (calculated MW of 93.4kDa according to NP_001034200.1). The observed molecular weight corresponds to fin...

Immunohistochemistry (IHC) of anti-LIN41 antibody

Anti-TRIM71 antibody IHC of human brain cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml.
Goat Anti-LIN41 Polyclonal Antibody – Cat# MBS246998

Western Blot (WB) of anti-LIN41 antibody

TRIM71 antibody (0.5 ug/ml) staining of HEK293 lysate (35 ug protein/ml in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Goat Anti-LIN41 Polyclonal Antibody, Western Blot (WB) – Cat# MBS246998

Other Notes

Small volumes of anti-LIN41 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for LIN41. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
E3 ubiquitin-protein ligase TRIM71
NCBI Official Synonym Full Names
tripartite motif containing 71, E3 ubiquitin protein ligase
NCBI Official Symbol
TRIM71
NCBI Official Synonym Symbols
LIN41; LIN-41
UniProt Protein Name
E3 ubiquitin-protein ligase TRIM71
UniProt Synonym Protein Names
Protein lin-41 homolog; Tripartite motif-containing protein 71
UniProt Gene Name
TRIM71
UniProt Synonym Gene Names
LIN41
UniProt Entry Name
LIN41_HUMAN
NCBI Protein Information
E3 ubiquitin-protein ligase TRIM71; protein lin-41 homolog; abnormal cell LINeage LIN-41; homolog of C. elegans Lin-41; tripartite motif-containing 71; tripartite motif-containing protein 71

UniProt Comments for LIN41

TRIM71: May be involved in controlling the timing of organ formation during development. Belongs to the TRIM/RBCC family.

Chromosomal Location of Human Ortholog: 3p22.3

Molecular Function: miRNA binding; zinc ion binding; ubiquitin-protein ligase activity; ligase activity

Biological Process: neural tube development; protein autoubiquitination; fibroblast growth factor receptor signaling pathway; neural tube closure; miRNA-mediated gene silencing, negative regulation of translation; G1/S transition of mitotic cell cycle
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-LIN41 antibody

Organs/Tissues associated with anti-LIN41 antibody

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