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TRH Receptor / TRHR (TRHR) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS247033

The thyrotropin-releasing hormone receptor (TRH-R), a Releasing Hormone Receptor, is activated by thyrotropin-releasing hormone. TRH-R may play a role in the etiopathogenesis of essential hypertension. More details

$650 / 0.05 mg +1 FREE 8GB USB
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Product Overview

Online Datasheet in PDF
Product Name
TRH Receptor / TRHR, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal to Human TRH Receptor / TRHR
Product Gene Name
Product Synonym Names
Anti-TRH Receptor / TRHR Antibody (C-Terminus) IHC-plus; TRHR; TRH receptor; TRH-R; Thyroliberin receptor; Human TRH Receptor; TRHR
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Gibbon, Gorilla, Horse, Human, Monkey, Mouse, Rat
Predicted Reactivity: Bovine, Dog, Hamster, Pig, Rabbit, Sheep (at least 90% immunogen sequence identity)
Form/Format
PBS, 0.1% sodium azide.
Purity/Purification
Immunoaffinity Purified
Concentration
1 mg/ml (lot specific)
Specificity
Human TRH Receptor. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Preparation and Storage
Long term: -70 degree C; Short term: +4 degree C
Molecular Weight
45,085 Da
OMIM
188545
3D Structure
ModBase 3D Structure for P34981
Target Species
Human
Immunogen Description
Synthetic 16 amino acid peptide from C-terminus of human TRH Receptor. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Elephant, Horse (100%).
Immunogen Type
Synthetic peptide
Immunogen
TRH Receptor / TRHR antibody was raised against synthetic 16 amino acid peptide from C-terminus of human TRH Receptor. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Elephant, Horse (100%); Sheep, Dog, Bovine, Hamster, Panda, Rabbit, Pig (94%); Opossum (88%).
Antigen Modification
C-Terminus
Applications Tested/Suitable for anti-TRHR antibody
Immunohistochemistry (IHC - Paraffin)
Application Notes for anti-TRHR antibody
IHC-P (10 ug/ml)

Immunohistochemistry (IHC) of anti-TRHR antibody

Anti-TRH Receptor antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Rabbit Anti-TRHR Polyclonal Antibody – Cat# MBS247033

Other Notes

Small volumes of anti-TRHR antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TRHR purchase

MBS247033 is an antibody targeting TRHR. Also known as Rabbit Polyclonal to Human TRH Receptor / TRHR. Reactive in Gibbon, Gorilla, Horse, Human, Monkey, Mouse, Rat
Predicted Reactivity: Bovine, Dog, Hamster, Pig, Rabbit, Sheep (at least 90% immunogen sequence identity). Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for TRHR. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
thyrotropin-releasing hormone receptor
NCBI Official Synonym Full Names
thyrotropin-releasing hormone receptor
NCBI Official Symbol
TRHR
NCBI Official Synonym Symbols
TRH-R
UniProt Protein Name
Thyrotropin-releasing hormone receptor
UniProt Synonym Protein Names
Thyroliberin receptor
UniProt Gene Name
TRHR
UniProt Synonym Gene Names
TRH-R
UniProt Entry Name
TRFR_HUMAN
NCBI Protein Information
thyrotropin-releasing hormone receptor; thyroliberin receptor

NCBI Summary for TRHR

This gene encodes a G protein-coupled receptor for thyrotropin-releasing hormone (TRH). Upon binding to TRH, this receptor activates the inositol phospholipid-calcium-protein kinase C transduction pathway. Mutations in this gene have been associated with generalized thyrotropin-releasing hormone resistance. [provided by RefSeq, Sep 2011]
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UniProt Comments for TRHR

TRHR: Receptor for thyrotropin-releasing hormone. This receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family.

Protein type: Membrane protein, integral; GPCR, family 1; Membrane protein, multi-pass; Receptor, GPCR

Chromosomal Location of Human Ortholog: 8q23

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: thyrotropin-releasing hormone receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-TRHR antibody

Organs/Tissues associated with anti-TRHR antibody

 Organ/Tissue Name  Pubmed Publications
 Mixed Antibodies  >2 publications with TRHR and Mixed
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