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MCHR2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS247050

MCHR2/GPR145 is a Melanin-Concentrating Hormone Receptor. Melanin-concentrating hormone plays an important role in the control of feeding behaviors and energy metabolism. Unlike MCH1, MCH2 signaling is not sensitive to pertussis toxin, and MCH2 cannot reduce… More details

$630 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
MCHR2, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal to Human MCHR2
Product Gene Name
Product Synonym Names
Anti-MCHR2 Antibody (Cytoplasmic Domain) IHC-plus; MCHR2; G protein-coupled receptor slt; GPRv17; GPR145; G protein-coupled receptor 145; G-protein coupled receptor 145; MCH receptor 2; MCHR-2; MCH-2R; MCH-R2; MCH2; Mch2 receptor; SLT receptor; MCH2R; SLT; Human MCHR2
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Gibbon, Gorilla, Human, Monkey
Predicted Reactivity: Dog, Horse (at least 90% immunogen sequence identity)
Form/Format
PBS, 0.1% sodium azide.
Purity/Purification
Immunoaffinity Purified
Concentration
1 mg/ml (lot specific)
Specificity
Human MCHR2. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except REEP4 (44%).
Preparation and Storage
Long term: -70 degree C; Short term: +4 degree C
Molecular Weight
38,849 Da
OMIM
606111
3D Structure
ModBase 3D Structure for Q969V1
Target Species
Human
Immunogen Description
Synthetic 16 amino acid peptide from 1st cytoplasmic domain of human MCHR2. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset (100%); Dog, Panda, Horse, Platypus (94%); Bat, Elephant, Pig, Xenopus (88%).
Immunogen Type
Synthetic peptide
Immunogen
MCHR2 antibody was raised against synthetic 16 amino acid peptide from 1st cytoplasmic domain of human MCHR2. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset (100%); Dog, Panda, Horse, Platypus (94%); Bat, Elephant, Pig, Xenopus (88%); Bovine (81%).
Antigen Modification
Cytoplasmic Domain
Applications Tested/Suitable for anti-MCHR2 antibody
Immunohistochemistry (IHC - Paraffin)
Application Notes for anti-MCHR2 antibody
IHC-P (8 - 19 ug/ml)

Immunohistochemistry (IHC) of anti-MCHR2 antibody

Anti-MCHR2 antibody IHC of human brain, neurons. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Rabbit Anti-MCHR2 Polyclonal Antibody – Cat# MBS247050

Other Notes

Small volumes of anti-MCHR2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MCHR2 purchase

MBS247050 is an antibody targeting MCHR2. Also known as Rabbit Polyclonal to Human MCHR2. Reactive in Gibbon, Gorilla, Human, Monkey
Predicted Reactivity: Dog, Horse (at least 90% immunogen sequence identity). Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for MCHR2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
melanin-concentrating hormone receptor 2
NCBI Official Synonym Full Names
melanin-concentrating hormone receptor 2
NCBI Official Symbol
MCHR2
NCBI Official Synonym Symbols
SLT; MCH2; MCH2R; GPR145; GPRv17; MCH-2R; MCH-R2; MCHR-2
UniProt Protein Name
Melanin-concentrating hormone receptor 2
UniProt Synonym Protein Names
G-protein coupled receptor 145; GPRv17; MCH-2R; MCH2; MCH2R
UniProt Gene Name
MCHR2
UniProt Synonym Gene Names
GPR145; SLT; MCH receptor 2; MCH-R2; MCHR-2; MCH2; MCH2R
UniProt Entry Name
MCHR2_HUMAN
NCBI Protein Information
melanin-concentrating hormone receptor 2; MCH receptor 2; G protein-coupled receptor 145; G protein-coupled receptor slt; G-protein coupled receptor 145; melanin-concentrating hormone 2

UniProt Comments for MCHR2

MCHR2: Receptor for melanin-concentrating hormone, coupled to G proteins that activate phosphoinositide hydrolysis. Belongs to the G-protein coupled receptor 1 family.

Protein type: Receptor, GPCR; GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 6q16

Cellular Component: integral to membrane; plasma membrane

Molecular Function: G-protein coupled receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-MCHR2 antibody

Organs/Tissues associated with anti-MCHR2 antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >14 publications with MCHR2 and Brain
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