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NMBR Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS247080

The neuromedin B receptor, a Bombesin Receptor, activates phospholipase and protein kinase C and enhances calcium mobilization. It binds neuromedin B, a potent mitogen and growth factor for normal and neoplastic lung and for gastrointestinal epithelial… More details

$630 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
NMBR, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal to Human NMBR
Product Gene Name
Product Synonym Names
Anti-NMBR Antibody (C-Terminus) IHC-plus; NMBR; Bombesin BB1 receptor; Neuromedin-B receptor; Neuromedin B receptor; NMB-preferring receptor; NMB-R; Human NMBR
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Gibbon, Gorilla, Human
Form/Format
PBS, 0.1% sodium azide.
Purity/Purification
Immunoaffinity Purified
Concentration
1 mg/ml (lot specific)
Specificity
Human NMBR. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Preparation and Storage
Long term: -70 degree C; Short term: +4 degree C
Molecular Weight
43,435 Da
OMIM
162341
3D Structure
ModBase 3D Structure for P28336
Target Species
Human
Immunogen Description
Synthetic 19 amino acid peptide from C-terminus of human NMBR. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon (100%); Monkey, Marmoset, Mouse, Elephant, Bovine (89%); Rat, Panda, Dog, Bat, Rabbit, Pig, Platypus (84%).
Immunogen Type
Synthetic peptide
Immunogen
NMBR antibody was raised against synthetic 19 amino acid peptide from C-terminus of human NMBR. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon (100%); Monkey, Marmoset, Mouse, Elephant, Bovine (89%); Rat, Panda, Dog, Bat, Rabbit, Pig, Platypus (84%).
Antigen Modification
C-Terminus
Applications Tested/Suitable for anti-NMBR antibody
Immunohistochemistry (IHC - Paraffin)
Application Notes for anti-NMBR antibody
IHC-P (9 ug/ml)

Immunohistochemistry (IHC) of anti-NMBR antibody

Anti-NMBR antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Rabbit Anti-NMBR Polyclonal Antibody – Cat# MBS247080

Immunohistochemistry (IHC) of anti-NMBR antibody

Anti-NMBR antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Rabbit Anti-NMBR Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS247080

Immunohistochemistry (IHC) of anti-NMBR antibody

Anti-NMBR antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Rabbit Anti-NMBR Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS247080

Immunohistochemistry (IHC) of anti-NMBR antibody

Anti-NMBR antibody IHC of human brain, pituitary. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Rabbit Anti-NMBR Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS247080

Other Notes

Small volumes of anti-NMBR antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for NMBR purchase

MBS247080 is an antibody targeting NMBR. Also known as Rabbit Polyclonal to Human NMBR. Reactive in Gibbon, Gorilla, Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for NMBR. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
neuromedin-B receptor
NCBI Official Synonym Full Names
neuromedin B receptor
NCBI Official Symbol
NMBR
NCBI Official Synonym Symbols
BB1
UniProt Protein Name
Neuromedin-B receptor
UniProt Synonym Protein Names
Epididymis tissue protein Li 185a; Neuromedin-B-preferring bombesin receptor
Protein Family
UniProt Gene Name
NMBR
UniProt Synonym Gene Names
NMB-R
UniProt Entry Name
NMBR_HUMAN
NCBI Protein Information
neuromedin-B receptor; NMB-R; bombesin receptor 1; epididymis tissue protein Li 185a; neuromedin-B-preferring bombesin receptor

NCBI Summary for NMBR

Neuromedin B receptor binds neuromedin B, a potent mitogen and growth factor for normal and neoplastic lung and for gastrointestinal epithelial tissue. [provided by RefSeq, Jul 2008]

UniProt Comments for NMBR

NMBR: Receptor for neuromedin-B. Belongs to the G-protein coupled receptor 1 family.

Protein type: Membrane protein, integral; GPCR, family 1; Receptor, GPCR; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 6q24.1

Cellular Component: integral to plasma membrane; cytoplasm; plasma membrane

Molecular Function: bombesin receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway; bombesin receptor signaling pathway; G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-NMBR antibody

Organs/Tissues associated with anti-NMBR antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >9 publications with NMBR and Brain
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