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PHLDA2 Antibody – Goat Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS247103

MBS247103 is an antibody targeting PHLDA2. Also known as Goat Polyclonal to Human PHLDA2 / TSSC3. Reactive in Gorilla, HumanPredicted Reactivity: Gibbon (at least 90% immunogen sequence identity). Host: Goat. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Product Name
PHLDA2 / TSSC3, Polyclonal Antibody
Full Product Name
Goat Polyclonal to Human PHLDA2 / TSSC3
Product Gene Name
Product Synonym Gene Name
TSSC3
Product Synonym Names
Anti-PHLDA2 / TSSC3 Antibody (C-Terminus) IHC-plus; PHLDA2; BWR1C; IPL; HLDA2; p17-BWR1C; BRW1C; TSSC3; Tumor-supressing STF cDNA 3; Human PHLDA2; TSSC3
Clonality
Polyclonal
Host
Goat
Species Reactivity
Gorilla, Human
Predicted Reactivity: Gibbon (at least 90% immunogen sequence identity)
Form/Format
Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Purity/Purification
Immunoaffinity Purified
Concentration
0.5 mg/ml (lot specific)
Specificity
Human PHLDA2.
Preparation and Storage
Store at -20 degree C. Minimize freezing and thawing.
Molecular Weight
17,092 Da
OMIM
602131
3D Structure
ModBase 3D Structure for Q53GA4
Target Species
Human
Immunogen Description
Synthetic peptide C-EPSRPSPQPKPRTP from the C-terminus of human PHLDA2 (NP_003302.1). Percent identity by BLAST analysis: Human, Gorilla (100%); Gibbon (93%); Marmoset (86%).
Immunogen Type
Synthetic peptide
Immunogen
PHLDA2 / TSSC3 antibody was raised against synthetic peptide C-EPSRPSPQPKPRTP from the C-terminus of human PHLDA2 (NP_003302.1). Percent identity by BLAST analysis: Human, Gorilla (100%); Gibbon (93%); Marmoset (86%).
Antigen Modification
C-Terminus
Applications Tested/Suitable for anti-PHLDA2 antibody
Immunohistochemistry (IHC - Paraffin), ELISA (EIA)
Application Notes for anti-PHLDA2 antibody
ELISA (1:32000), IHC-P (3.75 ug/ml)

Immunohistochemistry (IHC) of anti-PHLDA2 antibody

Anti-PHLDA2 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml.
Goat Anti-PHLDA2 Polyclonal Antibody – Cat# MBS247103

Immunohistochemistry (IHC) of anti-PHLDA2 antibody

Anti-PHLDA2 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml.
Goat Anti-PHLDA2 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS247103

Other Notes

Small volumes of anti-PHLDA2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for PHLDA2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
pleckstrin homology-like domain family A member 2
NCBI Official Synonym Full Names
pleckstrin homology-like domain, family A, member 2
NCBI Official Symbol
PHLDA2
NCBI Official Synonym Symbols
IPL; BRW1C; BWR1C; HLDA2; TSSC3
UniProt Protein Name
Pleckstrin homology-like domain family A member 2
UniProt Synonym Protein Names
Beckwith-Wiedemann syndrome chromosomal region 1 candidate gene C protein; Imprinted in placenta and liver protein; Tumor-suppressing STF cDNA 3 protein; Tumor-suppressing subchromosomal transferable fragment candidate gene 3 protein; p17-Beckwith-Wiedemann region 1 C; p17-BWR1C
UniProt Gene Name
PHLDA2
UniProt Synonym Gene Names
BWR1C; HLDA2; IPL; TSSC3; p17-BWR1C
UniProt Entry Name
PHLA2_HUMAN
NCBI Protein Information
pleckstrin homology-like domain family A member 2; p17-BWR1C; tumor-supressing STF cDNA 3; p17-Beckwith-Wiedemann region 1C; p17-Beckwith-Wiedemann region 1 C; tumor-suppressing STF cDNA 3 protein; imprinted in placenta and liver protein; tumor suppressing subtransferable candidate 3; tumor suppressing subchromosomal transferable fragment cDNA 3; beckwith-Wiedemann syndrome chromosomal region 1 candidate gene C protein; tumor-suppressing subchromosomal transferable fragment candidate gene 3 protein

NCBI Summary for PHLDA2

This gene is located in a cluster of imprinted genes on chromosome 11p15.5, which is considered to be an important tumor suppressor gene region. Alterations in this region may be associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. This gene has been shown to be imprinted, with preferential expression from the maternal allele in placenta and liver. [provided by RefSeq, Oct 2010]
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UniProt Comments for PHLDA2

PHLDA2: a protein may play a role in regulating placenta growth. Contains one PH domain. Expressed in placenta and adult prostate gland. Expressed at low levels in adult liver and lung, and fetal liver. Expressed in adult brain and neuroblastoma, medullablastoma and glioblastoma cell lines.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 11p15.4

Cellular Component: membrane; cytoplasm

Biological Process: organ morphogenesis; regulation of gene expression; apoptosis; regulation of embryonic development; regulation of cell migration; placenta development
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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