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GALNT10 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS247145

MBS247145 is an antibody targeting GALNT10. Also known as Rabbit Polyclonal to Human GALNT10. Reactive in Human, Mouse, Rat. Host: Rabbit. More details

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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Product Name
GALNT10, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal to Human GALNT10
Product Gene Name
anti-GALNT10 antibody
Product Synonym Names
Anti-GALNT10 Antibody (N-Terminus) IHC-plus; GALNT10; GalNAc transferase 10; GalNac-T10; GALNACT10; PPGALNACT10; PPGANTASE10; Pp-GaNTase 10; Human GALNT10
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
PBS, 0.02% sodium azide
Purity/Purification
Immunoaffinity Purified
Concentration
1 mg/ml (lot specific)
Specificity
Human GALNT10
Preparation and Storage
Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles. Store undiluted.
Molecular Weight
31,833 Da
OMIM
608043
3D Structure
ModBase 3D Structure for Q86SR1
Target Species
Human
Immunogen Description
A 16 amino acid peptide near the amino terminus of human GALNT10.
Immunogen Type
Synthetic peptide
Immunogen
GALNT10 antibody was raised against a 16 amino acid peptide near the amino terminus of human GALNT10.
Antigen Modification
N-Terminus
Applications Tested/Suitable for anti-GALNT10 antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)
Application Notes for anti-GALNT10 antibody
ELISA, IHC-P (5 ug/ml), WB (1 - 2 ug/ml)
Usage: GALNT10 antibody can be used for detection of GALNT10 by Western blot at 1-2 ug/ml.

Immunohistochemistry (IHC) of anti-GALNT10 antibody

Anti-GALNT10 antibody IHC of human thyroid. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Rabbit Anti-GALNT10 Polyclonal Antibody – Cat# MBS247145

Immunohistochemistry (IHC) of anti-GALNT10 antibody

Anti-GALNT10 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Rabbit Anti-GALNT10 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS247145

Immunofluorescence (IF) of anti-GALNT10 antibody

Immunofluorescence of GALNT10 in human brain tissue with GALNT10 antibody at 20 ug/ml.
Rabbit Anti-GALNT10 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS247145

Western Blot (WB) of anti-GALNT10 antibody

Western blot of GALNT10 in rat brain tissue lysate with GALNT10 antibody at (A) 1 and (B) 2 ug/ml.
Rabbit Anti-GALNT10 Polyclonal Antibody, Western Blot (WB) – Cat# MBS247145

Other Notes

Small volumes of anti-GALNT10 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for GALNT10. It may not necessarily be applicable to this product.

NCBI GI #
38195093
NCBI GeneID
55568
NCBI Accession #
NP_060010.3
UniProt Primary Accession #
Q86SR1
UniProt Secondary Accession #
Q6IN56; Q86VP8; Q8IXJ2; Q8TEJ2; Q96IV2; Q9H8E1; Q9Y4M4; B3KXC9
UniProt Related Accession #
Q86SR1
GenBank Nucleotide #
NM_017540.3
NCBI Official Synonym Full Names
polypeptide N-acetylgalactosaminyltransferase 10
NCBI Official Symbol
GALNT10
NCBI Official Synonym Symbols
GALNACT10; PPGALNACT10; PPGANTASE10
UniProt Protein Name
Polypeptide N-acetylgalactosaminyltransferase 10
UniProt Synonym Protein Names
Polypeptide GalNAc transferase 10; GalNAc-T10; pp-GaNTase 10; Protein-UDP acetylgalactosaminyltransferase 10; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 10
Protein Family
Polypeptide N-acetylgalactosaminyltransferase
UniProt Gene Name
GALNT10
UniProt Synonym Gene Names
GalNAc-T10; pp-GaNTase 10
UniProt Entry Name
GLT10_HUMAN
NCBI Protein Information
polypeptide N-acetylgalactosaminyltransferase 10

NCBI Summary for GALNT10

This gene encodes a member of the GalNAc polypeptide N-acetylgalactosaminyltransferases. These enzymes catalyze the first step in the synthesis of mucin-type oligosaccharides. These proteins transfer GalNAc from UDP-GalNAc to either serine or threonine residues of polypeptide acceptors. The protein encoded by this locus may have increased catalytic activity toward glycosylated peptides compared to activity toward non-glycosylated peptides.[provided by RefSeq, Apr 2010]
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UniProt Comments for GALNT10

GALNT10: Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D- galactosamine residue to a serine or threonine residue on the protein receptor. Has activity toward Muc5Ac and EA2 peptide substrates. Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Glycan Metabolism - O-glycan biosynthesis; Transferase; EC 2.4.1.41

Chromosomal Location of Human Ortholog: 5q33.2

Cellular Component: Golgi membrane; integral to membrane

Molecular Function: polypeptide N-acetylgalactosaminyltransferase activity; metal ion binding; carbohydrate binding

Biological Process: protein amino acid O-linked glycosylation; cellular protein metabolic process; O-glycan processing; post-translational protein modification
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Research Articles on GALNT10

1. our results reveal a novel Hnf4alpha/miR-122/GALNT10 regulatory pathway that facilitates EGF miR-122 activation and hepatoma growth in HBV-associated hepatocarcinogenesis.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-GALNT10 antibody

 Products by Pathway  Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
 Mucin Type O-Glycan Biosynthesis Pathway antibodies  Mucin Type O-Glycan Biosynthesis Pathway Diagram
 Mucin Type O-Glycan Biosynthesis Pathway antibodies  Mucin Type O-Glycan Biosynthesis Pathway Diagram
 O-glycan Biosynthesis, Mucin Type Core Pathway antibodies  O-glycan Biosynthesis, Mucin Type Core Pathway Diagram
 O-glycan Biosynthesis, Mucin Type Core Pathway antibodies  O-glycan Biosynthesis, Mucin Type Core Pathway Diagram
 O-linked Glycosylation Pathway antibodies  O-linked Glycosylation Pathway Diagram
 O-linked Glycosylation Of Mucins Pathway antibodies  O-linked Glycosylation Of Mucins Pathway Diagram
 Post-translational Protein Modification Pathway antibodies  Post-translational Protein Modification Pathway Diagram
 Mucin Core 1 And Core 2 O-glycosylation Pathway antibodies  Mucin Core 1 And Core 2 O-glycosylation Pathway Diagram

Diseases associated with anti-GALNT10 antibody

 Disease Name  Pubmed Publications
 Carcinoma Antibodies  >2 publications with GALNT10 and Carcinoma
 Carcinoma, Hepatocellular Antibodies  >1 publications with GALNT10 and Carcinoma, Hepatocellular
 Kidney Diseases Antibodies  >1 publications with GALNT10 and Kidney Diseases
 Necrosis Antibodies  >1 publications with GALNT10 and Necrosis

Organs/Tissues associated with anti-GALNT10 antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >2 publications with GALNT10 and Brain
 Liver Antibodies  >1 publications with GALNT10 and Liver
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