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LPAR4 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS247233

MBS247233 is an antibody targeting LPAR4. Also known as Rabbit Polyclonal to Human LPAR4 / GPR23. Reactive in Bat, Gibbon, Dog, Gorilla, Hamster, Horse, Human, Monkey, Mouse, Rabbit, RatPredicted Reactivity: Bovine, Pig, Chicken (at least 90% immunogen… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
LPAR4 / GPR23, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal to Human LPAR4 / GPR23
Product Gene Name
Product Synonym Gene Name
GPR23
Product Synonym Names
Anti-LPAR4 / GPR23 Antibody (Cytoplasmic Domain) IHC-plus; LPAR4; G-protein coupled receptor 23; LPA-4; p2RY9; p2Y5-LIKE; p2Y purinoceptor 9; p2Y5-like receptor; p2Y9; G protein-coupled receptor 23; GPR23; LPA receptor 4; LPA4; Purinergic receptor 9; Human LPAR4; GPR23
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Bat, Gibbon, Dog, Gorilla, Hamster, Horse, Human, Monkey, Mouse, Rabbit, Rat
Predicted Reactivity: Bovine, Pig, Chicken (at least 90% immunogen sequence identity)
Form/Format
PBS, 0.1% sodium azide.
Purity/Purification
Immunoaffinity Purified
Concentration
1 mg/ml (lot specific)
Specificity
Human LPAR4 / GPR23. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Preparation and Storage
Long term: -70 degree C; Short term: +4 degree C
Molecular Weight
41,895 Da
OMIM
300086
3D Structure
ModBase 3D Structure for Q99677
Target Species
Human
Immunogen Description
Synthetic 17 amino acid peptide from 3rd cytoplasmic domain of human LPAR4 / GPR23. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Dog, Bat, Horse, Rabbit (100%).
Immunogen Type
Synthetic peptide
Immunogen
LPAR4 / GPR23 antibody was raised against synthetic 17 amino acid peptide from 3rd cytoplasmic domain of human LPAR4 / GPR23. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Dog, Bat, Horse, Rabbit (100%); Bovine, Pig, Opossum, Turkey, Chicken (94%); Xenopus (88%).
Antigen Modification
Cytoplasmic Domain
Applications Tested/Suitable for anti-LPAR4 antibody
Immunohistochemistry (IHC - Paraffin)
Application Notes for anti-LPAR4 antibody
IHC-P (4 ug/ml)

Immunohistochemistry (IHC) of anti-LPAR4 antibody

Anti-LPAR4 / GPR23 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Rabbit Anti-LPAR4 Polyclonal Antibody – Cat# MBS247233

Immunohistochemistry (IHC) of anti-LPAR4 antibody

Anti-LPAR4 / GPR23 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Rabbit Anti-LPAR4 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS247233

Other Notes

Small volumes of anti-LPAR4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for LPAR4. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
lysophosphatidic acid receptor 4
NCBI Official Synonym Full Names
lysophosphatidic acid receptor 4
NCBI Official Symbol
LPAR4
NCBI Official Synonym Symbols
LPA4; P2Y9; GPR23; P2RY9; P2Y5-LIKE
UniProt Protein Name
Lysophosphatidic acid receptor 4
UniProt Synonym Protein Names
G-protein coupled receptor 23; P2Y purinoceptor 9; P2Y9; P2Y5-like receptor; Purinergic receptor 9
UniProt Gene Name
LPAR4
UniProt Synonym Gene Names
GPR23; LPA4; P2RY9; LPA receptor 4; LPA-4; P2Y9
UniProt Entry Name
LPAR4_HUMAN
NCBI Protein Information
lysophosphatidic acid receptor 4; LPA-4; LPA receptor 4; P2Y purinoceptor 9; P2Y5-like receptor; purinergic receptor 9; G protein-coupled receptor 23; G-protein coupled receptor 23

NCBI Summary for LPAR4

This gene encodes a member of the lysophosphatidic acid receptor family. It may also be related to the P2Y receptors, a family of receptors that bind purine and pyrimidine nucleotides and are coupled to G proteins. The encoded protein may play a role in monocytic differentiation. [provided by RefSeq, Feb 2009]
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UniProt Comments for LPAR4

LPAR4: Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. Transduces a signal by increasing the intracellular calcium ions and by stimulating adenylyl cyclase activity. The rank order of potency for agonists of this receptor is 1-oleoyl- > 1-stearoyl- > 1-palmitoyl- > 1-myristoyl- > 1- alkyl- > 1-alkenyl-LPA. Belongs to the G-protein coupled receptor 1 family.

Protein type: Receptor, GPCR; GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: Xq21.1

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: G-protein coupled receptor activity; lipid binding

Biological Process: G-protein coupled receptor protein signaling pathway
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-LPAR4 antibody

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