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PILRB Antibody – Goat Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS247388

MBS247388 is an antibody targeting PILRB. Also known as Goat Polyclonal to Human PILRB. Reactive in Human. Host: Goat. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
PILRB, Polyclonal Antibody
Full Product Name
Goat Polyclonal to Human PILRB
Product Gene Name
Product Synonym Names
Anti-PILRB Antibody IHC-plus; PILRB; Activating receptor PILR-beta; Activating receptor PILRbeta; Cell surface receptor FDFACT; Cell surface receptor FDFACT1; Cell surface receptor FDFACT2; FDFACT2; FDFACT1; FDFACT; Human PILRB
Clonality
Polyclonal
Host
Goat
Species Reactivity
Human
Form/Format
Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Purity/Purification
Immunoaffinity Purified
Concentration
0.5 mg/ml (lot specific)
Specificity
Human PILRB. Both variants represent identical proteins (NP_038468.3; NP_839956.1). This antibody is expected to recognize isoform a only (NP_038468.3; NP_839956.1).
Preparation and Storage
Store at -20 degree C. Minimize freezing and thawing.
Molecular Weight
29,630 Da
OMIM
605342
3D Structure
ModBase 3D Structure for Q9UKJ0
Target Species
Human
Immunogen Description
Synthetic peptide C-RVTESKGHSESWH from an internal region of human PILRB (NP_038468.3; NP_839956.1). Percent identity with other species by BLAST analysis: Human (100%).
Immunogen Type
Synthetic peptide
Immunogen
PILRB antibody was raised against synthetic peptide C-RVTESKGHSESWH from an internal region of human PILRB (NP_038468.3; NP_839956.1). Percent identity with other species by BLAST analysis: Human (100%).
Applications Tested/Suitable for anti-PILRB antibody
Immunohistochemistry (IHC - Paraffin), ELISA (EIA)
Application Notes for anti-PILRB antibody
ELISA, IHC-P (3 - 6 ug/ml)
Usage: Peptide ELISA: antibody detection limit dilution 1:16000. Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH...

Immunohistochemistry (IHC) of anti-PILRB antibody

Anti-PILRB antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3 ug/ml.
Goat Anti-PILRB Polyclonal Antibody – Cat# MBS247388

Immunohistochemistry (IHC) of anti-PILRB antibody

Anti-PILRB antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3 ug/ml.
Goat Anti-PILRB Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS247388

Immunohistochemistry (IHC) of anti-PILRB antibody

Anti-PILRB antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3 ug/ml.
Goat Anti-PILRB Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS247388

Other Notes

Small volumes of anti-PILRB antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for PILRB. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Synonym Full Names
paired immunoglobin-like type 2 receptor beta
NCBI Official Symbol
PILRB
NCBI Official Synonym Symbols
FDFACT1; FDFACT2
UniProt Protein Name
Paired immunoglobulin-like type 2 receptor beta
UniProt Synonym Protein Names
Activating receptor PILR-beta; Cell surface receptor FDFACT
UniProt Gene Name
PILRB
UniProt Synonym Gene Names
FDFACT
UniProt Entry Name
PILRB_HUMAN
NCBI Protein Information
paired immunoglobulin-like type 2 receptor beta

NCBI Summary for PILRB

The paired immunoglobin-like type 2 receptors consist of highly related activating and inhibitory receptors that are involved in the regulation of many aspects of the immune system. The paired immunoglobulin-like receptor genes are located in a tandem head-to-tail orientation on chromosome 7. This gene encodes the activating member of the receptor pair and contains a truncated cytoplasmic tail relative to its inhibitory counterpart (PILRA), that has a long cytoplasmic tail with immunoreceptor tyrosine-based inhibitory (ITIM) motifs. This gene is thought to have arisen from a duplication of the inhibitory PILRA gene and evolved to acquire its activating function. [provided by RefSeq, Jun 2013]
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UniProt Comments for PILRB

PILRB: Paired receptors consist of highly related activating and inhibitory receptors and are widely involved in the regulation of the immune system. PILRB is thought to act as a cellular signaling activating receptor that associates with ITAM-bearing adapter molecules on the cell surface. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Immunoglobulin superfamily

Chromosomal Location of Human Ortholog: 7q22.1

Cellular Component: integral to plasma membrane

Molecular Function: protein binding

Biological Process: transmembrane receptor protein tyrosine kinase activation (dimerization); transmembrane receptor protein tyrosine kinase signaling pathway
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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