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TAAR6 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS247470

TAAR6 is classified as an Orphan-A GPCR because the ligand has not been identified. TAAR6 was identified by degenerate PCR because of its similarity to other trace amine receptors. The close proximity on chromosome 6 and high sequence homology to the other… More details

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Product Overview

Online Datasheet in PDF
Product Name
TAAR6, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal to Human TAAR6
Product Gene Name
anti-TAAR6 antibody
Product Synonym Names
Anti-TAAR6 Antibody (C-Terminus) IHC-plus; TAAR6; TA4; TaR-4; TAR4; TAR6; TaR-6; TRAR4; Trace amine receptor 4; Trace amine receptor 6; RP11-295F4.3; Human TAAR6
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Chimpanzee, Human, Monkey
Predicted Reactivity: Rabbit (at least 90% immunogen sequence identity)
Form/Format
PBS, 0.1% sodium azide.
Purity/Purification
Immunoaffinity Purified
Concentration
1 mg/ml (lot specific)
Specificity
Human TAAR6. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Preparation and Storage
Long term: -70 degree C; Short term: +4 degree C
Molecular Weight
38,451 Da
OMIM
608923
3D Structure
ModBase 3D Structure for Q96RI8
Target Species
Human
Immunogen Description
Synthetic 14 amino acid peptide from C-terminus of human TAAR6. Percent identity with other species by BLAST analysis: Human, Chimpanzee, Monkey, Marmoset (100%); Rabbit (93%); Bovine, Hamster (86%).
Immunogen Type
Synthetic peptide
Immunogen
TAAR6 antibody was raised against synthetic 14 amino acid peptide from C-terminus of human TAAR6. Percent identity with other species by BLAST analysis: Human, Chimpanzee, Monkey, Marmoset (100%); Rabbit (93%); Bovine, Hamster (86%).
Antigen Modification
C-Terminus

Product Categories/Family for anti-TAAR6 antibody

Family: GPCR; Subfamily: Orphan-A
Applications Tested/Suitable for anti-TAAR6 antibody
Immunohistochemistry (IHC - Paraffin)
Application Notes for anti-TAAR6 antibody
IHC-P (3 - 6 ug/ml)

Immunohistochemistry (IHC) of anti-TAAR6 antibody

Anti-TAAR6 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Rabbit Anti-TAAR6 Polyclonal Antibody – Cat# MBS247470

Immunohistochemistry (IHC) of anti-TAAR6 antibody

Anti-TAAR6 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Rabbit Anti-TAAR6 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS247470

Immunohistochemistry (IHC) of anti-TAAR6 antibody

Anti-TAAR6 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Rabbit Anti-TAAR6 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS247470

Immunohistochemistry (IHC) of anti-TAAR6 antibody

Anti-TAAR6 antibody IHC of human kidney, renal tubules. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Rabbit Anti-TAAR6 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS247470

Other Notes

Small volumes of anti-TAAR6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TAAR6 purchase

MBS247470 is an antibody targeting TAAR6. Also known as Rabbit Polyclonal to Human TAAR6. Reactive in Chimpanzee, Human, Monkey
Predicted Reactivity: Rabbit (at least 90% immunogen sequence identity). Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for TAAR6. It may not necessarily be applicable to this product.

NCBI GI #
28173558
NCBI GeneID
319100
NCBI Accession #
NP_778237.1
UniProt Primary Accession #
Q96RI8
UniProt Secondary Accession #
Q5VUQ4
UniProt Related Accession #
Q96RI8
GenBank Nucleotide #
NM_175067.1
NCBI Official Full Name
trace amine-associated receptor 6
NCBI Official Synonym Full Names
trace amine associated receptor 6
NCBI Official Symbol
TAAR6
NCBI Official Synonym Symbols
TA4; TAR4; TAR6; TRAR4; taR-4; taR-6
UniProt Protein Name
Trace amine-associated receptor 6
UniProt Synonym Protein Names
Trace amine receptor 4; TaR-4
Protein Family
Trace amine-associated receptor
UniProt Gene Name
TAAR6
UniProt Synonym Gene Names
TA4; TAR4; TRAR4; TaR-6; Trace amine receptor 6; TaR-4
UniProt Entry Name
TAAR6_HUMAN
NCBI Protein Information
trace amine-associated receptor 6; trace amine receptor 4; trace amine receptor 6

NCBI Summary for TAAR6

This gene encodes a seven-transmembrane G-protein-coupled receptor that likely functions as a receptor for endogenous trace amines. Mutations in this gene may be associated with schizophrenia.[provided by RefSeq, Feb 2010]

UniProt Comments for TAAR6

TAAR6: Orphan receptor. Could be a receptor for trace amines. Trace amines are biogenic amines present in very low levels in mammalian tissues. Although some trace amines have clearly defined roles as neurotransmitters in invertebrates, the extent to which they function as true neurotransmitters in vertebrates has remained speculative. Trace amines are likely to be involved in a variety of physiological functions that have yet to be fully understood. Belongs to the G-protein coupled receptor 1 family.

Protein type: Membrane protein, multi-pass; GPCR, family 1; Membrane protein, integral; Receptor, GPCR

Chromosomal Location of Human Ortholog: 6q23.2

Cellular Component: integral to membrane; plasma membrane

Molecular Function: G-protein coupled receptor activity; trace-amine receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway
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Research Articles on TAAR6

1. The results of this study suggested a possible role of TAAR6 in antidepressant response and suicide behavior in patients with depressive disorder

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-TAAR6 antibody

 Reference Product  PubMed Publications
 DTNBP1 antibody  >1 publications with TAAR6 and DTNBP1
 STX7 antibody  >1 publications with TAAR6 and STX7
 DAOA antibody  >1 publications with TAAR6 and DAOA

Pathways associated with anti-TAAR6 antibody

 Products by Pathway  Pathway Diagram
 Amine Ligand-binding Receptors Pathway antibodies  Amine Ligand-binding Receptors Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway antibodies  Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 G Alpha (s) Signalling Events Pathway antibodies  G Alpha (s) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 Metabolic Disorders Of Biological Oxidation Enzymes Pathway antibodies  Metabolic Disorders Of Biological Oxidation Enzymes Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram

Diseases associated with anti-TAAR6 antibody

 Disease Name  Pubmed Publications
 Schizophrenia Antibodies  >9 publications with TAAR6 and Schizophrenia
 Cardiovascular Diseases Antibodies  >1 publications with TAAR6 and Cardiovascular Diseases
 Vascular Diseases Antibodies  >1 publications with TAAR6 and Vascular Diseases
 Dementia Antibodies  >1 publications with TAAR6 and Dementia
 Nervous System Diseases Antibodies  >1 publications with TAAR6 and Nervous System Diseases
 Cognition Disorders Antibodies  >1 publications with TAAR6 and Cognition Disorders
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