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GPR1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS247516

GPR1 is an Orphan-A GPCR with an unknown ligand. GPR1 was identified in a search for genes responsible for mediating brain reward and may have a role in drug addiction. It has also been shown to act as an HIV coreceptor in kidney mesangial cells (Tokizawa et… More details

$630 / 0.05 mg +1 FREE 8GB USB
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Sample Manual Insert View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
GPR1, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal to Human GPR1
Product Gene Name
Product Synonym Names
Anti-GPR1 Antibody (N-Terminus) IHC-plus; GPR1; G-protein coupled receptor 1; G protein-coupled receptor 1; Gpr-1; Human GPR1
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Gibbon, Gorilla, Human
Predicted Reactivity: Monkey (at least 90% immunogen sequence identity)
Form/Format
PBS, 0.1% sodium azide.
Purity/Purification
Immunoaffinity Purified
Concentration
1 mg/ml (lot specific)
Specificity
Human GPR1. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Preparation and Storage
Long term: -70 degree C; Short term: +4 degree C
Molecular Weight
41,431 Da
OMIM
600239
3D Structure
ModBase 3D Structure for P46091
Usage Not Recommended
Immunocytochemistry (ICC)
Target Species
Human
Immunogen Description
Synthetic 19 amino acid peptide from N-terminal extracellular domain of human GPR1. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon (100%); Monkey, Marmoset (95%); Hamster, Dog (84%).
Immunogen Type
Synthetic peptide
Immunogen
GPR1 antibody was raised against synthetic 19 amino acid peptide from N-terminal extracellular domain of human GPR1. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon (100%); Monkey, Marmoset (95%); Hamster, Dog (84%).
Antigen Modification
N-Terminus
Applications Tested/Suitable for anti-GPR1 antibody
Immunohistochemistry (IHC - Paraffin)
Application Notes for anti-GPR1 antibody
IHC-P (32 ug/ml)

Immunohistochemistry (IHC) of anti-GPR1 antibody

Anti-GPR1 antibody IHC of human brain, cerebellum, Purkinje neurons. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 32 ug/ml.
Rabbit Anti-GPR1 Polyclonal Antibody – Cat# MBS247516

Immunohistochemistry (IHC) of anti-GPR1 antibody

Anti-GPR1 antibody IHC of human brain, neurons. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 32 ug/ml.
Rabbit Anti-GPR1 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS247516

Transfection of anti-GPR1 antibody

 
Rabbit Anti-GPR1 Polyclonal Antibody, Transfection – Cat# MBS247516

Transfection Control of anti-GPR1 antibody

 
Rabbit Anti-GPR1 Polyclonal Antibody, Transfection Control – Cat# MBS247516

Other Notes

Small volumes of anti-GPR1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GPR1 purchase

MBS247516 is an antibody targeting GPR1. Also known as Rabbit Polyclonal to Human GPR1. Reactive in Gibbon, Gorilla, Human
Predicted Reactivity: Monkey (at least 90% immunogen sequence identity). Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for GPR1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
G-protein coupled receptor 1
NCBI Official Synonym Full Names
G protein-coupled receptor 1
NCBI Official Symbol
GPR1
UniProt Protein Name
G-protein coupled receptor 1
UniProt Gene Name
GPR1
UniProt Entry Name
GPR1_HUMAN
NCBI Protein Information
G-protein coupled receptor 1; probable G-protein coupled receptor 1

UniProt Comments for GPR1

GPR1: Receptor for the inflammation-associated leukocyte chemoattractant chemerin/RARRES2 suggesting a role for this receptor in the regulation of inflammation. Can act as a coreceptor for HIV-1. Belongs to the G-protein coupled receptor 1 family.

Protein type: Receptor, GPCR; Membrane protein, multi-pass; GPCR, family 1; Membrane protein, integral

Chromosomal Location of Human Ortholog: 2q33.3

Cellular Component: neuron projection; integral to plasma membrane

Molecular Function: G-protein coupled receptor activity; neuropeptide binding

Biological Process: G-protein coupled receptor protein signaling pathway; G-protein signaling, coupled to cyclic nucleotide second messenger; synaptic transmission; neuropeptide signaling pathway
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-GPR1 antibody

Pathways associated with anti-GPR1 antibody

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