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GPR35 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS247610

MBS247610 is an antibody targeting GPR35. Also known as Rabbit Polyclonal to Human GPR35. Reactive in HumanPredicted Reactivity: Gorilla, Gibbon (at least 90% immunogen sequence identity). Host: Rabbit. GPR35 is an Orphan-A GPCR with an unknown ligand. More details

$630 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
GPR35, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal to Human GPR35
Product Gene Name
Product Synonym Names
Anti-GPR35 Antibody (C-Terminus) IHC-plus; GPR35; KYNA receptor; Kynurenic acid receptor; G protein-coupled receptor 35; G-protein coupled receptor 35; Human GPR35
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Predicted Reactivity: Gorilla, Gibbon (at least 90% immunogen sequence identity)
Form/Format
PBS, 0.1% sodium azide.
Purity/Purification
Immunoaffinity Purified
Concentration
1 mg/ml (lot specific)
Specificity
Human GPR35. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Preparation and Storage
Long term: -70 degree C; Short term: +4 degree C
Molecular Weight
37,452 Da
OMIM
602646
3D Structure
ModBase 3D Structure for Q9HC97
Target Species
Human
Immunogen Description
Synthetic 19 amino acid peptide from C-terminus of human GPR35. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon (95%); Monkey (89%); Marmoset, Bat (84%).
Immunogen Type
Synthetic peptide
Immunogen
GPR35 antibody was raised against synthetic 19 amino acid peptide from C-terminus of human GPR35. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon (95%); Monkey (89%); Marmoset, Bat (84%).
Antigen Modification
C-Terminus
Applications Tested/Suitable for anti-GPR35 antibody
Immunohistochemistry (IHC - Paraffin), Immunocytochemistry (ICC)
Application Notes for anti-GPR35 antibody
ICC, IHC-P (12 - 23 ug/ml)

Immunohistochemistry (IHC) of anti-GPR35 antibody

Anti-GPR35 antibody IHC of human Pancreas, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Rabbit Anti-GPR35 Polyclonal Antibody – Cat# MBS247610

Immunohistochemistry (IHC) of anti-GPR35 antibody

Anti-GPR35 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Rabbit Anti-GPR35 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS247610

Immunohistochemistry (IHC) of anti-GPR35 antibody

Anti-GPR35 antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Rabbit Anti-GPR35 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS247610

Immunohistochemistry (IHC) of anti-GPR35 antibody

Anti-GPR35 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Rabbit Anti-GPR35 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS247610

Transfection of anti-GPR35 antibody

Anti-GPR35 antibody immunocytochemistry (ICC) staining of HEK293 human embryonic kidney cells transfected with GPR35.
Rabbit Anti-GPR35 Polyclonal Antibody, Transfection – Cat# MBS247610

Other Notes

Small volumes of anti-GPR35 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for GPR35. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
G-protein coupled receptor 35 isoform a
NCBI Official Synonym Full Names
G protein-coupled receptor 35
NCBI Official Symbol
GPR35
UniProt Protein Name
G-protein coupled receptor 35
UniProt Synonym Protein Names
Kynurenic acid receptor; KYNA receptor
UniProt Gene Name
GPR35
UniProt Synonym Gene Names
KYNA receptor
UniProt Entry Name
GPR35_HUMAN
NCBI Protein Information
G-protein coupled receptor 35; KYNA receptor; kynurenic acid receptor

UniProt Comments for GPR35

GPR35: Acts as a receptor for kynurenic acid, an intermediate in the tryptophan metabolic pathway. The activity of this receptor is mediated by G-proteins that elicit calcium mobilization and inositol phosphate production through G(qi/o) proteins. Belongs to the G-protein coupled receptor 1 family.

Protein type: GPCR, family 1; Membrane protein, multi-pass; Receptor, GPCR; Membrane protein, integral

Chromosomal Location of Human Ortholog: 2q37.3

Cellular Component: integral to plasma membrane

Molecular Function: G-protein coupled receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-GPR35 antibody

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