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INADL Antibody – Goat Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS247671

MBS247671 is an antibody targeting INADL. Also known as Goat Polyclonal to Human INADL / PATJ. Reactive in Gibbon, Bovine, Human, Monkey, RabbitPredicted Reactivity: Bat, Dog, Horse (at least 90% immunogen sequence identity). Host: Goat. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
INADL / PATJ, Polyclonal Antibody
Full Product Name
Goat Polyclonal to Human INADL / PATJ
Product Gene Name
Product Synonym Gene Name
PATJ
Product Synonym Names
Anti-INADL / PATJ Antibody (N-Terminus) IHC-plus; INADL; Cipp; HINADL; InaD-like (Drosophila); InaD-like protein; InaD-like; Inadl protein; PATJ; Inadl; c-term variant3; PDZ domain protein; Human INADL; PATJ
Clonality
Polyclonal
Host
Goat
Species Reactivity
Gibbon, Bovine, Human, Monkey, Rabbit
Predicted Reactivity: Bat, Dog, Horse (at least 90% immunogen sequence identity)
Form/Format
Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Purity/Purification
Immunoaffinity Purified
Concentration
0.5 mg/ml (lot specific)
Specificity
Human INADL.
Preparation and Storage
Store at -20 degree C. Minimize freezing and thawing.
Molecular Weight
125,231 Da
OMIM
603199
3D Structure
ModBase 3D Structure for Q8NI35
Target Species
Human
Immunogen Description
Synthetic peptide PENPATDKLQVLQ-C from the N-terminus of human INADL (NP_795352.2). Percent identity by BLAST analysis: Human, Gibbon, Marmoset, Bovine, Rabbit (100%); Panda, Dog, Bat, Horse (92%); Elephant, Turkey, Chicken (85%).
Immunogen Type
Synthetic peptide
Immunogen
INADL / PATJ antibody was raised against synthetic peptide PENPATDKLQVLQ-C from the N-terminus of human INADL (NP_795352.2). Percent identity by BLAST analysis: Human, Gibbon, Marmoset, Bovine, Rabbit (100%); Panda, Dog, Bat, Horse (92%); Elephant, Turkey, Chicken (85%).
Antigen Modification
N-Terminus
Applications Tested/Suitable for anti-INADL antibody
Immunohistochemistry (IHC - Paraffin), ELISA (EIA)
Application Notes for anti-INADL antibody
ELISA (1:32000), IHC-P (3.75 ug/ml)

Immunohistochemistry (IHC) of anti-INADL antibody

Anti-INADL antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml.
Goat Anti-INADL Polyclonal Antibody – Cat# MBS247671

Other Notes

Small volumes of anti-INADL antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for INADL. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
inaD-like protein
NCBI Official Synonym Full Names
InaD-like (Drosophila)
NCBI Official Symbol
INADL
NCBI Official Synonym Symbols
Cipp; PATJ; hINADL; InaD-like
UniProt Protein Name
InaD-like protein
UniProt Synonym Protein Names
Pals1-associated tight junction protein; Protein associated to tight junctions
UniProt Gene Name
INADL
UniProt Synonym Gene Names
PATJ; Inadl protein; hINADL
UniProt Entry Name
INADL_HUMAN
NCBI Protein Information
inaD-like protein; PDZ domain protein; protein associated to tight junctions; channel-interacting PDZ domain protein; PALS1-associated tight junction protein; inactivation no after-potential D-like protein

NCBI Summary for INADL

This gene encodes a protein with multiple PDZ domains. PDZ domains mediate protein-protein interactions, and proteins with multiple PDZ domains often organize multimeric complexes at the plasma membrane. This protein localizes to tight junctions and to the apical membrane of epithelial cells. A similar protein in Drosophila is a scaffolding protein which tethers several members of a multimeric signaling complex in photoreceptors. [provided by RefSeq, Jul 2008]
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UniProt Comments for INADL

INADL: Scaffolding protein that may bring different proteins into adjacent positions at the cell membrane. May regulate protein targeting, cell polarity and integrity of tight junctions. May regulate the surface expression and/or function of ASIC3 in sensory neurons. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: 1p31.3

Cellular Component: tight junction; protein complex; perinuclear region of cytoplasm; apical plasma membrane; plasma membrane

Molecular Function: protein binding

Biological Process: intercellular junction assembly and maintenance
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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