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GPR12 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS247780

GPR12 has been identified as a constitutively active Lysophospholipid/Lysosphingolipid receptor. More details

$650 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
GPR12, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal to Human GPR12
Product Gene Name
Product Synonym Names
Anti-GPR12 Antibody (Extracellular Domain) IHC-plus; GPR12; G protein-coupled receptor 12; G-protein coupled receptor 12; GPCR12; GPCR21; Human GPR12
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Gibbon, Bovine, Gorilla, Hamster, Horse, Human, Mouse, Pig, Rabbit, Rat
Predicted Reactivity: Monkey, Bat, Dog, Chicken, Xenopus (at least 90% immunogen sequence identity)
Form/Format
PBS, 0.1% sodium azide.
Purity/Purification
Immunoaffinity Purified
Concentration
1 mg/ml (lot specific)
Specificity
Human GPR12 / GPCR12. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except GPR6 (53%).
Preparation and Storage
Long term: -70 degree C; Short term: +4 degree C
Molecular Weight
36,730 Da
OMIM
600752
3D Structure
ModBase 3D Structure for P47775
Target Species
Human
Immunogen Description
Synthetic 15 amino acid peptide from 2nd extracellular domain of human GPR12 / GPCR12. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Bovine, Horse, Rabbit, Pig (100%).
Immunogen Type
Synthetic peptide
Immunogen
GPR12 antibody was raised against synthetic 15 amino acid peptide from 2nd extracellular domain of human GPR12 / GPCR12. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Bovine, Horse, Rabbit, Pig (100%); Monkey, Dog, Bat, Opossum, Turkey, Chicken, Xenopus (93%); Platypus, Pufferfish (87%); Stickleback (80%).
Antigen Modification
Extracellular Domain
Applications Tested/Suitable for anti-GPR12 antibody
Immunohistochemistry (IHC - Paraffin)
Application Notes for anti-GPR12 antibody
IHC-P (1.2 ug/ml)

Immunohistochemistry (IHC) of anti-GPR12 antibody

Anti-GPR12 / GPCR12 antibody IHC of human brain, pituitary. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Rabbit Anti-GPR12 Polyclonal Antibody – Cat# MBS247780

Other Notes

Small volumes of anti-GPR12 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GPR12 purchase

MBS247780 is an antibody targeting GPR12. Also known as Rabbit Polyclonal to Human GPR12. Reactive in Gibbon, Bovine, Gorilla, Hamster, Horse, Human, Mouse, Pig, Rabbit, Rat
Predicted Reactivity: Monkey, Bat, Dog, Chicken, Xenopus (at least 90% immunogen sequence identity). Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for GPR12. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
G-protein coupled receptor 12
NCBI Official Synonym Full Names
G protein-coupled receptor 12
NCBI Official Symbol
GPR12
NCBI Official Synonym Symbols
GPCR12; GPCR21; PPP1R84
UniProt Protein Name
G-protein coupled receptor 12
UniProt Gene Name
GPR12
UniProt Entry Name
GPR12_HUMAN
NCBI Protein Information
G-protein coupled receptor 12; protein phosphatase 1, regulatory subunit 84

UniProt Comments for GPR12

GPR12: Promotes neurite outgrowth and blocks myelin inhibition in neurons. Receptor with constitutive G(s) signaling activity that stimulates cyclic AMP production. Belongs to the G-protein coupled receptor 1 family.

Protein type: Receptor, GPCR; GPCR, family 1; Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 13q12

Cellular Component: integral to plasma membrane

Molecular Function: G-protein coupled receptor activity; phosphatidylcholine binding

Biological Process: cellular calcium ion homeostasis; G-protein coupled receptor protein signaling pathway
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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