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GPR45 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS247863

GPR45 is an Orphan-A GPCR with an unknown ligand. It is the mammalian ortholog of a putative lysophosphatidic acid receptor from Xenopus laevis. More details

$650 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
GPR45, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal to Human GPR45
Product Gene Name
Product Synonym Names
Anti-GPR45 Antibody (Cytoplasmic Domain) IHC-plus; GPR45; G protein-coupled receptor 45; PSP24(ALPHA); PSP24-1; PSP24; PSP24A; PSP24-alpha; Human GPR45
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Gibbon, Gorilla, Horse, Human, Monkey
Predicted Reactivity: Mouse (at least 90% immunogen sequence identity)
Form/Format
PBS, 0.1% sodium azide.
Purity/Purification
Immunoaffinity Purified
Concentration
1 mg/ml (lot specific)
Specificity
Human GPR45. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Preparation and Storage
Long term: -70 degree C; Short term: +4 degree C
Molecular Weight
41,967 Da
OMIM
604838
3D Structure
ModBase 3D Structure for Q9Y5Y3
Target Species
Human
Immunogen Description
Synthetic 16 amino acid peptide from 3rd cytoplasmic domain of human GPR45. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Elephant, Horse (100%); Mouse, Panda (94%); Rabbit (88%); Rat, Bat (81%).
Immunogen Type
Synthetic peptide
Immunogen
GPR45 antibody was raised against synthetic 16 amino acid peptide from 3rd cytoplasmic domain of human GPR45. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Elephant, Horse (100%); Mouse, Panda (94%); Rabbit (88%); Rat, Bat (81%).
Antigen Modification
Cytoplasmic Domain
Applications Tested/Suitable for anti-GPR45 antibody
Immunohistochemistry (IHC - Paraffin), Immunocytochemistry (ICC)
Application Notes for anti-GPR45 antibody
ICC, IHC-P (42 ug/ml)

Immunohistochemistry (IHC) of anti-GPR45 antibody

Anti-GPR45 antibody IHC of human Prostate, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Rabbit Anti-GPR45 Polyclonal Antibody – Cat# MBS247863

Immunohistochemistry (IHC) of anti-GPR45 antibody

Anti-GPR45 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Rabbit Anti-GPR45 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS247863

Immunohistochemistry (IHC) of anti-GPR45 antibody

Anti-GPR45 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Rabbit Anti-GPR45 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS247863

Immunohistochemistry (IHC) of anti-GPR45 antibody

Anti-GPR45 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Rabbit Anti-GPR45 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS247863

Transfection of anti-GPR45 antibody

Anti-GPR45 antibody immunocytochemistry (ICC) staining of HEK293 human embryonic kidney cells transfected with GPR45.
Rabbit Anti-GPR45 Polyclonal Antibody, Transfection – Cat# MBS247863

Transfection Control of anti-GPR45 antibody

Anti-GPR45 antibody immunocytochemistry (ICC) staining of untransfected HEK293 human embryonic kidney cells.
Rabbit Anti-GPR45 Polyclonal Antibody, Transfection Control – Cat# MBS247863

Other Notes

Small volumes of anti-GPR45 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GPR45 purchase

MBS247863 is an antibody targeting GPR45. Also known as Rabbit Polyclonal to Human GPR45. Reactive in Gibbon, Gorilla, Horse, Human, Monkey
Predicted Reactivity: Mouse (at least 90% immunogen sequence identity). Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for GPR45. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
probable G-protein coupled receptor 45
NCBI Official Synonym Full Names
G protein-coupled receptor 45
NCBI Official Symbol
GPR45
NCBI Official Synonym Symbols
PSP24; PSP24A; PSP24(ALPHA)
UniProt Protein Name
Probable G-protein coupled receptor 45
UniProt Synonym Protein Names
PSP24-1; PSP24-alpha
UniProt Gene Name
GPR45
UniProt Entry Name
GPR45_HUMAN
NCBI Protein Information
probable G-protein coupled receptor 45; PSP24-1; PSP24-alpha; high-affinity lysophosphatidic acid receptor

NCBI Summary for GPR45

This intronless gene encodes a member of the G protein-coupled receptor (GPCR) family. Members of this protein family contain seven putative transmembrane domains and may mediate signaling processes to the interior of the cell via activation of heterotrimeric G proteins. This protein may function in the central nervous system. [provided by RefSeq, Jul 2008]
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UniProt Comments for GPR45

GPR45: Orphan receptor. May play a role in brain function. Belongs to the G-protein coupled receptor 1 family.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR; GPCR, family 1

Chromosomal Location of Human Ortholog: 2q11.1-q12

Cellular Component: integral to membrane; plasma membrane

Molecular Function: G-protein coupled receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-GPR45 antibody

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