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CUEDC2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS247971

MBS247971 is an antibody targeting CUEDC2. Also known as Rabbit Polyclonal to Human CUEDC2. Reactive in Human, Mouse, Rat. Host: Rabbit. More details

$650 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CUEDC2, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal to Human CUEDC2
Product Gene Name
Product Synonym Names
Anti-CUEDC2 Antibody (C-Terminus) IHC-plus; CUEDC2; BA18I14.5; C10orf66; CUE domain containing 2; Human CUEDC2
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
PBS containing 0.02% sodium azide
Purity/Purification
Immunoaffinity Purified
Concentration
1 mg/ml (lot specific)
Preparation and Storage
Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles. Store undiluted.
Molecular Weight
32,009 Da
OMIM
614142
3D Structure
ModBase 3D Structure for Q9H467
Target Species
Human
Immunogen Description
A 19 amino acid peptide from near the carboxy terminus of human CUEDC2.
Immunogen Type
Synthetic peptide
Immunogen
CUEDC2 antibody was raised against a 19 amino acid peptide from near the carboxy terminus of human CUEDC2.
Antigen Modification
C-Terminus
Applications Tested/Suitable for anti-CUEDC2 antibody
Immunohistochemistry (IHC - Paraffin), Immunocytochemistry (ICC), Western Blot (WB), ELISA (EIA)
Application Notes for anti-CUEDC2 antibody
ELISA, ICC, IHC-P (5 ug/ml), WB (1 - 2 ug/ml)

Immunohistochemistry (IHC) of anti-CUEDC2 antibody

Anti-CUEDC2 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Rabbit Anti-CUEDC2 Polyclonal Antibody – Cat# MBS247971

Immunohistochemistry (IHC) of anti-CUEDC2 antibody

Anti-CUEDC2 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Rabbit Anti-CUEDC2 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS247971

Immunocytochemistry (ICC) of anti-CUEDC2 antibody

Immunocytochemistry in HeLa cells with CUEDC2 antibody at 5 µg/ml.
Rabbit Anti-CUEDC2 Polyclonal Antibody, Immunocytochemistry (ICC) – Cat# MBS247971

Western Blot (WB) of anti-CUEDC2 antibody

Western blot of CUEDC2 in HeLa cell lysate with CUEDC2 antibody at (A) 1 and (B) 2 ug/ml.
Rabbit Anti-CUEDC2 Polyclonal Antibody, Western Blot (WB) – Cat# MBS247971

Other Notes

Small volumes of anti-CUEDC2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CUEDC2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
CUE domain-containing protein 2
NCBI Official Synonym Full Names
CUE domain containing 2
NCBI Official Symbol
CUEDC2
NCBI Official Synonym Symbols
C10orf66; bA18I14.5
UniProt Protein Name
CUE domain-containing protein 2
UniProt Gene Name
CUEDC2
UniProt Synonym Gene Names
C10orf66
UniProt Entry Name
CUED2_HUMAN
NCBI Protein Information
CUE domain-containing protein 2

UniProt Comments for CUEDC2

CUEDC2: Down-regulates ESR1 protein levels through the ubiquitination-proteasome pathway, regardless of the presence of 17 beta-estradiol. Also involved in 17 beta-estradiol-induced ESR1 degradation. Controls PGR protein levels through a similar mechanism. May predict the clinical outcome of tamoxifen therapy of breast cancer patients. Patients with tumors that highly express CUEDC2 do not respond to tamoxifen treatment as effectively as those with tumors with low expression. Belongs to the CUEDC2 family.

Chromosomal Location of Human Ortholog: 10q24.32

Cellular Component: nucleoplasm; nuclear membrane; cytoplasm

Molecular Function: protein binding
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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