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SPIN Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS248009

MBS248009 is an antibody targeting SPIN. Also known as Rabbit Polyclonal (IgG) to Human SPIN / SPIN1. Reactive in Human, Mouse, Rat. Host: Rabbit. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
SPIN / SPIN1, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal (IgG) to Human SPIN / SPIN1
Product Gene Name
Product Synonym Gene Name
SPIN1
Product Synonym Names
Anti-SPIN / SPIN1 Antibody (aa111-160) IHC-plus; SPIN1; OCR; Ovarian cancer-related protein; Spindlin-1; SPIN; Spindlin; Spindlin 1; Human SPIN; SPIN1
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol
Purity/Purification
Immunoaffinity Purified
Concentration
1 mg/ml (lot specific)
Specificity
SPIN1 Antibody detects endogenous levels of total SPIN1 protein.
Preparation and Storage
Store at -20 degree C for up to one year.
Molecular Weight
29,601 Da
OMIM
609936
3D Structure
ModBase 3D Structure for Q9Y657
Target Species
Human
Immunogen Description
Synthetic peptide from human SPIN1 (aa111-160).
Immunogen
SPIN / SPIN1 antibody was raised against synthetic peptide from human SPIN1 (aa111-160).
Antigen Modification
aa111-160
Applications Tested/Suitable for anti-SPIN antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)
Application Notes for anti-SPIN antibody
ELISA (1:20000), IHC-P (10 ug/ml), WB (1:500 - 1:1000)

Immunohistochemistry (IHC) of anti-SPIN antibody

Anti-SPIN / SPIN1 antibody IHC staining of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Rabbit Anti-SPIN Polyclonal Antibody – Cat# MBS248009

Western Blot (WB) of anti-SPIN antibody

Western blot of extracts from HeLa cells, using SPIN1 Antibody. The lane on the right is treated with the synthesized peptide.
Rabbit Anti-SPIN Polyclonal Antibody, Western Blot (WB) – Cat# MBS248009

Other Notes

Small volumes of anti-SPIN antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for SPIN. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
spindlin-1
NCBI Official Synonym Full Names
spindlin 1
NCBI Official Symbol
SPIN1
NCBI Official Synonym Symbols
SPIN
UniProt Protein Name
Spindlin-1
UniProt Synonym Protein Names
Ovarian cancer-related protein; Spindlin1
Protein Family
UniProt Gene Name
SPIN1
UniProt Synonym Gene Names
OCR; SPIN
UniProt Entry Name
SPIN1_HUMAN
NCBI Protein Information
spindlin-1; spindlin1; ovarian cancer-related protein

UniProt Comments for SPIN

SPIN1: May play a role in cell-cycle regulation during the transition from gamete to embryo. Belongs to the SPIN/STSY family.

Protein type: DNA-binding; Nucleolus

Chromosomal Location of Human Ortholog: 9q22.1

Cellular Component: nucleolus; spindle; nucleus

Molecular Function: protein binding; methylated histone residue binding

Biological Process: Wnt receptor signaling pathway; meiotic cell cycle; gamete generation; multicellular organismal development; chromatin modification; positive regulation of Wnt receptor signaling pathway; rRNA transcription
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-SPIN antibody

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