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CAPG Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS248016

MBS248016 is an antibody targeting CAPG. Also known as Rabbit Polyclonal (IgG) to Human CAPG / MCP. Reactive in Human, Mouse, Rat. Host: Rabbit. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
CAPG / MCP, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal (IgG) to Human CAPG / MCP
Product Gene Name
Product Synonym Gene Name
MCP
Product Synonym Names
Anti-CAPG / MCP Antibody IHC-plus; CAPG; AFCP; Actin-regulatory protein CAP-G; Actin regulatory protein CAP-G; Gelsolin-like capping protein; MCP; Macrophage capping protein; Macrophage-capping protein; Human CAPG; MCP
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
PBS, pH 7.4, 0.05% sodium azide
Purity/Purification
Purified
Concentration
1 mg/ml (lot specific)
Specificity
CAPG antibody detects endogenous levels of CAPG protein. Not tested with other proteins.
Preparation and Storage
Store at -20 degree C for up to one year.
Molecular Weight
36,857 Da
OMIM
153615
3D Structure
ModBase 3D Structure for P40121
Target Species
Human
Immunogen Description
Synthetic peptide conjugated to KLH
Immunogen Type
Synthetic peptide - KLH conjugated
Applications Tested/Suitable for anti-CAPG antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)
Application Notes for anti-CAPG antibody
ELISA (1:10000), IHC-P (2.5 ug/ml), WB (1:250)

Immunohistochemistry (IHC) of anti-CAPG antibody

Human Lung, Macrophages: Formalin-Fixed, Paraffin-Embedded (FFPE)
Rabbit Anti-CAPG Polyclonal Antibody – Cat# MBS248016

Western Blot (WB) of anti-CAPG antibody

 
Rabbit Anti-CAPG Polyclonal Antibody, Western Blot (WB) – Cat# MBS248016

Other Notes

Small volumes of anti-CAPG antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CAPG. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
macrophage-capping protein isoform 1
NCBI Official Synonym Full Names
capping protein (actin filament), gelsolin-like
NCBI Official Symbol
CAPG
NCBI Official Synonym Symbols
MCP; AFCP; HEL-S-66
UniProt Protein Name
Macrophage-capping protein
UniProt Synonym Protein Names
Actin regulatory protein CAP-G
UniProt Gene Name
CAPG
UniProt Synonym Gene Names
AFCP; MCP
UniProt Entry Name
CAPG_HUMAN
NCBI Protein Information
macrophage-capping protein; macrophage capping protein; gelsolin-like capping protein; actin regulatory protein CAP-G; actin-regulatory protein CAP-G; epididymis secretory protein Li 66

NCBI Summary for CAPG

This gene encodes a member of the gelsolin/villin family of actin-regulatory proteins. The encoded protein reversibly blocks the barbed ends of F-actin filaments in a Ca2+ and phosphoinositide-regulated manner, but does not sever preformed actin filaments. By capping the barbed ends of actin filaments, the encoded protein contributes to the control of actin-based motility in non-muscle cells. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jan 2012]
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UniProt Comments for CAPG

CAPG: Calcium-sensitive protein which reversibly blocks the barbed ends of actin filaments but does not sever preformed actin filaments. May play an important role in macrophage function. May play a role in regulating cytoplasmic and/or nuclear structures through potential interactions with actin. May bind DNA. Belongs to the villin/gelsolin family.

Protein type: Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 2p11.2

Cellular Component: F-actin capping protein complex; melanosome; nucleus

Molecular Function: actin binding

Biological Process: protein complex assembly; cell projection biogenesis; barbed-end actin filament capping
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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