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TSPY1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS248018

MBS248018 is an antibody targeting TSPY1. Also known as Rabbit Polyclonal to Human TSPY1 / TSPY. Reactive in Human. Host: Rabbit. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
TSPY1 / TSPY, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal to Human TSPY1 / TSPY
Product Gene Name
Product Synonym Gene Name
TSPY
Product Synonym Names
Anti-TSPY1 / TSPY Antibody (C-Terminus) IHC-plus; TSPY1; Cancer/testis antigen 78; CT78; DYS14; PJA923; TSPY; Human TSPY1; TSPY
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
PBS, 0.02% sodium azide
Purity/Purification
Immunoaffinity Purified
Concentration
1 mg/ml (lot specific)
Specificity
Human TSPY1. TSPY1L antibody is human and mouse reactive. At least three isoforms of TSPY1 are known to exist; this antibody will detect only TSPY1L.
Preparation and Storage
Long term: -20 degree C; Short term: +4 degree C. Avoid repeat freeze-thaw cycles.
Molecular Weight
33,169 Da
OMIM
480100
3D Structure
ModBase 3D Structure for Q01534
Target Species
Human
Immunogen Description
A 20 amino acid peptide near the carboxy terminus of human TSPY1L.
Immunogen Type
Synthetic peptide
Immunogen
TSPY1 / TSPY antibody was raised against a 20 amino acid peptide near the carboxy terminus of human TSPY1L.
Antigen Modification
C-Terminus
Applications Tested/Suitable for anti-TSPY1 antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB)
Application Notes for anti-TSPY1 antibody
IHC-P (5 ug/ml), WB (0.5 - 1 ug/ml)
Usage: TSPY1L antibody can be used for detection of TSPY1L by Western blot at 0.5-1 ug/mL.

Immunohistochemistry (IHC) of anti-TSPY1 antibody

Anti-TSPY1 / TSPY antibody IHC staining of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Rabbit Anti-TSPY1 Polyclonal Antibody – Cat# MBS248018

Western Blot (WB) of anti-TSPY1 antibody

Western blot analysis of TSPY1L in A20 cell lysate with TSPY1L antibody at (A) 0.5 and (B) 1 ug/ml
Rabbit Anti-TSPY1 Polyclonal Antibody, Western Blot (WB) – Cat# MBS248018

Other Notes

Small volumes of anti-TSPY1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for TSPY1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
testis-specific Y-encoded protein 1 isoform TSPY-L
NCBI Official Synonym Full Names
testis specific protein, Y-linked 1
NCBI Official Symbol
TSPY1
NCBI Official Synonym Symbols
CT78; TSPY; DYS14; pJA923
UniProt Protein Name
Testis-specific Y-encoded protein 1
UniProt Synonym Protein Names
Cancer/testis antigen 78; CT78
UniProt Gene Name
TSPY1
UniProt Synonym Gene Names
TSPY; CT78
UniProt Entry Name
TSPY1_HUMAN
NCBI Protein Information
testis-specific Y-encoded protein 1; cancer/testis antigen 78

NCBI Summary for TSPY1

The protein encoded by this gene is found only in testicular tissue and may be involved in spermatogenesis. Approximately 35 copies of this gene are present in humans, but only a single, nonfunctional orthologous gene is found in mouse. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2010]
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UniProt Comments for TSPY1

TSPY1: May be involved in sperm differentiation and proliferation. TSPY is located in the gonadoblastoma critical region and is preferentially expressed in tumor germ cells of gonadoblastoma specimens. Expression also correlates with testicular seminoma and tumorigenesis of the prostate gland. Belongs to the nucleosome assembly protein (NAP) family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cancer Testis Antigen (CTA)

Chromosomal Location of Human Ortholog: Yp11.2

Cellular Component: cytoplasm; nucleus

Molecular Function: protein binding

Biological Process: cell proliferation; nucleosome assembly; gonadal mesoderm development; spermatogenesis; cell differentiation; sex differentiation

Disease: Gonadoblastoma
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with anti-TSPY1 antibody

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