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SDR Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS248059

MBS248059 is an antibody targeting SDR. Also known as Rabbit Polyclonal (IgG) to Human SDR / SDPR. Reactive in Human. Host: Rabbit. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
SDR / SDPR, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal (IgG) to Human SDR / SDPR
Product Gene Name
Product Synonym Gene Name
SDPR
Product Synonym Names
Anti-SDR / SDPR Antibody (N-Terminus) IHC-plus; SDPR; Cavin-2; CAVIN2; PS-p68; SDR; Serum deprivation response; Human SDR; SDPR
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
PBS, 0.02% sodium azide.
Purity/Purification
Immunoaffinity Purified
Concentration
1 mg/ml (lot specific)
Specificity
It is predicted to not cross-react with other members of the cavin family.
Preparation and Storage
Long term: -20 degree C; Short term: +4 degree C. Avoid repeat freeze-thaw cycles.
Molecular Weight
47,173 Da
OMIM
606728
3D Structure
ModBase 3D Structure for O95810
Target Species
Human
Immunogen Description
18 amino acid peptide near the amino terminus of human SDPR.
Immunogen
SDR / SDPR antibody was raised against 18 amino acid peptide near the amino terminus of human SDPR.
Antigen Modification
N-Terminus
Applications Tested/Suitable for anti-SDR antibody
Immunohistochemistry (IHC - Paraffin), Immunofluorescence (IF), Western Blot (WB), ELISA (EIA)
Application Notes for anti-SDR antibody
ELISA, IF (20 ug/ml), IHC-P (10 ug/ml), WB (1 - 2 ug/ml)

Immunohistochemistry (IHC) of anti-SDR antibody

Anti-SDR / SDPR antibody IHC staining of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Rabbit Anti-SDR Polyclonal Antibody – Cat# MBS248059

Immunofluorescence (IF) of anti-SDR antibody

Immunofluorescence of SDPR in human spleen tissue with SDPR antibody at 20 ug/ml.
Rabbit Anti-SDR Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS248059

Western Blot (WB) of anti-SDR antibody

Western blot analysis of SDPR in HeLa cell lysate with SDPR antibody at (A) 1 and (B) 2 ug/ml
Rabbit Anti-SDR Polyclonal Antibody, Western Blot (WB) – Cat# MBS248059

Other Notes

Small volumes of anti-SDR antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for SDR. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
serum deprivation-response protein
NCBI Official Synonym Full Names
serum deprivation response
NCBI Official Symbol
SDPR
NCBI Official Synonym Symbols
SDR; CAVIN2; PS-p68; cavin-2
UniProt Protein Name
Serum deprivation-response protein
UniProt Synonym Protein Names
Cavin-2; PS-p68; Phosphatidylserine-binding protein
Protein Family
UniProt Gene Name
SDPR
UniProt Entry Name
SDPR_HUMAN
NCBI Protein Information
serum deprivation-response protein; SDPR; phosphatidylserine binding protein; phosphatidylserine-binding protein

NCBI Summary for SDR

This gene encodes a calcium-independent phospholipid-binding protein whose expression increases in serum-starved cells. This protein is a substrate for protein kinase C (PKC) phosphorylation and recruits polymerase I and transcript release factor (PTRF) to caveolae. Removal of this protein causes caveolae loss and its over-expression results in caveolae deformation and membrane tubulation.[provided by RefSeq, Sep 2009]
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UniProt Comments for SDR

SDPR: May play a role in targeting PRKCA to caveolae. Belongs to the PTRF/SDPR family.

Protein type: Lipid-binding

Chromosomal Location of Human Ortholog: 2q32-q33

Cellular Component: cytoplasm; caveola; cytosol

Molecular Function: protein binding; protein kinase C binding; phosphatidylserine binding; phospholipid binding
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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