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PPFIA3 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS248144

MBS248144 is an antibody targeting PPFIA3. Also known as Rabbit Polyclonal (IgG) to Human PPFIA3. Reactive in Human, Mouse, Rat. Host: Rabbit. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Product Name
PPFIA3, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal (IgG) to Human PPFIA3
Product Gene Name
Product Synonym Names
Anti-PPFIA3 Antibody (C-Terminus) IHC-plus; PPFIA3; LIPRIN; Liprin-alpha 3; LPNA3; KIAA0654; Liprin-alpha-3; Human PPFIA3
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
PBS, 0.02% sodium azide.
Purity/Purification
Immunoaffinity Purified
Concentration
1 mg/ml (lot specific)
Specificity
PPFIA3 antibody is human, mouse, and rat reactive.
Preparation and Storage
Long term: -20 degree C; Short term: +4 degree C. Avoid repeat freeze-thaw cycles.
Molecular Weight
132,365 Da
OMIM
603144
3D Structure
ModBase 3D Structure for O75145
Target Species
Human
Immunogen Description
17 amino acid peptide near the carboxy terminus of human PPFIA3.
Immunogen
PPFIA3 antibody was raised against 17 amino acid peptide near the carboxy terminus of human PPFIA3.
Antigen Modification
C-Terminus
Applications Tested/Suitable for anti-PPFIA3 antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)
Application Notes for anti-PPFIA3 antibody
ELISA, IHC-P (10 ug/ml), WB (1 - 2 ug/ml)

Immunohistochemistry (IHC) of anti-PPFIA3 antibody

Anti-PPFIA3 antibody IHC staining of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Rabbit Anti-PPFIA3 Polyclonal Antibody – Cat# MBS248144

Western Blot (WB) of anti-PPFIA3 antibody

Western blot analysis of PPFIA3 in 293 cell lysate with PPFIA3 antibody at (A) 1 and (B) 2 ug/ml.
Rabbit Anti-PPFIA3 Polyclonal Antibody, Western Blot (WB) – Cat# MBS248144

Other Notes

Small volumes of anti-PPFIA3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for PPFIA3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
liprin-alpha-3
NCBI Official Synonym Full Names
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
NCBI Official Symbol
PPFIA3
NCBI Official Synonym Symbols
LPNA3
UniProt Protein Name
Liprin-alpha-3
UniProt Synonym Protein Names
Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3; PTPRF-interacting protein alpha-3
Protein Family
UniProt Gene Name
PPFIA3
UniProt Synonym Gene Names
KIAA0654; PTPRF-interacting protein alpha-3
UniProt Entry Name
LIPA3_HUMAN
NCBI Protein Information
liprin-alpha-3; liprin-alpha 3; PTPRF-interacting protein alpha-3; protein tyrosine phosphatase, receptor type, f polypeptide, alpha 3; protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3

NCBI Summary for PPFIA3

The protein encoded by this gene is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. Liprin family protein has been shown to localize phosphatase LAR to cell focal adhesions and may be involved in the molecular organization of presynaptic active zones. [provided by RefSeq, Jul 2008]
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UniProt Comments for PPFIA3

PPFIA3: a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. May localize receptor-like tyrosine phosphatases type 2A at specific sites on the plasma membrane, possibly regulating their interaction with the extracellular environment and their association with substrates. Contains 3 SAM (sterile alpha motif) domains. Two alternatively spliced isoforms have been described

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: 19q13.33

Cellular Component: cell surface; presynaptic active zone; cytosol

Molecular Function: protein binding

Biological Process: synaptic transmission; glutamate secretion; neurotransmitter secretion; regulation of short-term neuronal synaptic plasticity
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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