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PABPC3 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS248207

MBS248207 is an antibody targeting PABPC3. Also known as Rabbit Polyclonal to Human PABPC3. Reactive in Human. Host: Rabbit. More details

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Product Overview

Product Name
PABPC3, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal to Human PABPC3
Product Gene Name
anti-PABPC3 antibody
Product Synonym Names
Anti-PABPC3 Antibody (aa107-323) IHC-plus; PABPC3; PABP3; TPABP; PABP-3; Poly(A)-binding protein 3; PABPL3; Poly(A)-binding protein-like 3; Testis PABP; Human PABPC3
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
0.1 M Tris-glycine, pH 7.0, 20% glycerol, 0.01% Thimerosal
Purity/Purification
Immunoaffinity Purified
Concentration
0.83 mg/ml (lot specific)
Specificity
Human PABPC3
Preparation and Storage
Keep as concentrated solution. Aliquot and store at -20 degree C or below. Avoid multiple freeze-thaw cycles.
Molecular Weight
70,031 Da
OMIM
604680
3D Structure
ModBase 3D Structure for Q9H361
Target Species
Human
Immunogen Description
Recombinant fragment corresponding to a region within amino acids 107 and 323 of PABPC3 (SwissProt Q9H361). Percent identity by BLAST analysis: Human (100%); Rat (84%).
Immunogen Type
Recombinant protein
Immunogen
PABPC3 antibody was raised against recombinant fragment corresponding to a region within amino acids 107 and 323 of PABPC3 (SwissProt Q9H361). Percent identity by BLAST analysis: Human (100%); Rat (84%).
Antigen Modification
aa107-323
Applications Tested/Suitable for anti-PABPC3 antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB)
Application Notes for anti-PABPC3 antibody
IHC-P (10 ug/ml), WB (1:500 - 1:3000)
Usage: IHC-paraffin: Suggested antigen retrieval using heat mediated 10 mM Citrate buffer (pH 6.0) or Tris-EDTA buffer (pH 8.0).

Immunohistochemistry (IHC) of anti-PABPC3 antibody

Anti-PABPC3 antibody IHC staining of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Rabbit Anti-PABPC3 Polyclonal Antibody – Cat# MBS248207

Immunohistochemistry (IHC) of anti-PABPC3 antibody

IHC of paraffin-embedded SCM1 xenograft using PABPC3 antibody at 1:100 dilution.
Rabbit Anti-PABPC3 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS248207

Western Blot (WB) of anti-PABPC3 antibody

Sample (30 ug of whole cell lysate). A: JurKat. 7.5% SDS PAGE. PABPC3 antibody diluted at 1:1000.
Rabbit Anti-PABPC3 Polyclonal Antibody, Western Blot (WB) – Cat# MBS248207

Other Notes

Small volumes of anti-PABPC3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for PABPC3. It may not necessarily be applicable to this product.

NCBI GI #
45238849
NCBI GeneID
5042
NCBI Accession #
NP_112241.2
UniProt Primary Accession #
Q9H361
UniProt Secondary Accession #
Q8NHV0; Q9H086
UniProt Related Accession #
Q9H361
GenBank Nucleotide #
NM_030979.2
NCBI Official Full Name
polyadenylate-binding protein 3
NCBI Official Synonym Full Names
poly(A) binding protein, cytoplasmic 3
NCBI Official Symbol
PABPC3
NCBI Official Synonym Symbols
PABP3; tPABP; PABPL3
UniProt Protein Name
Polyadenylate-binding protein 3
UniProt Synonym Protein Names
Testis-specific poly(A)-binding protein
UniProt Gene Name
PABPC3
UniProt Synonym Gene Names
PABP3; PABPL3; PABP-3; Poly(A)-binding protein 3
UniProt Entry Name
PABP3_HUMAN
NCBI Protein Information
polyadenylate-binding protein 3; PABP-3; testis PABP; poly(A)-binding protein 3; poly(A)-binding protein-like 3; testis-specific poly(A)-binding protein 3; testis-specific poly(A)-binding protein (PABP)

NCBI Summary for PABPC3

Messenger RNA stability and translation initiation are extensively under the control of poly(A)-binding proteins (PABP). See PABPC1 (MIM 604679) for background information.[supplied by OMIM, Jul 2002]

UniProt Comments for PABPC3

PABP 3: Binds the poly(A) tail of mRNA. May be involved in cytoplasmic regulatory processes of mRNA metabolism. Binds poly(A) with a slightly lower affinity as compared to PABPC1. Belongs to the polyadenylate-binding protein type-1 family.

Protein type: RNA-binding

Chromosomal Location of Human Ortholog: 13q12-q13

Cellular Component: cytoplasm

Molecular Function: nucleotide binding; poly(A) binding

Biological Process: mRNA metabolic process
Show more

Research Articles on PABPC3

1. molecular cloning and expression in testis

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-PABPC3 antibody

 Products by Pathway  Pathway Diagram
 RNA Degradation Pathway antibodies  RNA Degradation Pathway Diagram
 RNA Degradation Pathway antibodies  RNA Degradation Pathway Diagram
 RNA Transport Pathway antibodies  RNA Transport Pathway Diagram
 RNA Transport Pathway antibodies  RNA Transport Pathway Diagram
 MRNA Surveillance Pathway antibodies  MRNA Surveillance Pathway Diagram
 MRNA Surveillance Pathway antibodies  MRNA Surveillance Pathway Diagram

Diseases associated with anti-PABPC3 antibody

 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >1 publications with PABPC3 and Nervous System Diseases

Organs/Tissues associated with anti-PABPC3 antibody

 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >1 publications with PABPC3 and Muscle
 Blood Antibodies  >1 publications with PABPC3 and Blood
 Testis Antibodies  >1 publications with PABPC3 and Testis
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