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GNRH Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS248210

MBS248210 is an antibody targeting GNRH. Also known as Rabbit Polyclonal to Human GNRH. Reactive in Human. Host: Rabbit. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
GNRH, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal to Human GNRH
Product Gene Name
Product Synonym Gene Name
GNRH1
Product Synonym Names
Anti-GNRH Antibody (aa11-60) IHC-plus; GNRH1; Gonadoliberin; LHRH; LNRH; GnRH-associated peptide 1; Progonadoliberin-1; Progonadoliberin I; Luliberin I; GNRH; GRH; HH12; Human GNRH
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
PBS, pH 7.2, 0.05% sodium azide
Purity/Purification
Immunoaffinity Purified
Concentration
1 mg/ml (lot specific)
Specificity
Human GNRH
Preparation and Storage
Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Molecular Weight
10,380 Da
OMIM
gene 614841
3D Structure
ModBase 3D Structure for P01148
Target Species
Human
Immunogen Description
Synthetic peptide around Asp43 of human GNRH
Immunogen Type
Synthetic peptide
Antigen Modification
aa11-60

Product Categories/Family for anti-GNRH antibody

Applications Tested/Suitable for anti-GNRH antibody
Immunohistochemistry (IHC - Paraffin)
Application Notes for anti-GNRH antibody
IHC-P (15 ug/ml)

Immunohistochemistry (IHC) of anti-GNRH antibody

Anti-GNRH antibody IHC staining of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 15 ug/ml.
Rabbit Anti-GNRH Polyclonal Antibody – Cat# MBS248210

Other Notes

Small volumes of anti-GNRH antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for GNRH. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
progonadoliberin-1 preproprotein
NCBI Official Synonym Full Names
gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
NCBI Official Symbol
GNRH1
NCBI Official Synonym Symbols
GRH; GNRH; HH12; LHRH; LNRH
UniProt Protein Name
Progonadoliberin-1
UniProt Synonym Protein Names
Progonadoliberin ICleaved into the following 2 chains:Gonadoliberin-1Alternative name(s):Gonadoliberin I; Gonadorelin; Gonadotropin-releasing hormone I; GnRH-I; Luliberin I; Luteinizing hormone-releasing hormone I; LH-RH I
Protein Family
UniProt Gene Name
GNRH1
UniProt Synonym Gene Names
GNRH; GRH; LHRH; GnRH-I; LH-RH I
UniProt Entry Name
GON1_HUMAN
NCBI Protein Information
progonadoliberin-1; luliberin I; progonadoliberin I; GnRH-associated peptide 1; prolactin release-inhibiting factor; gonadotropin-releasing hormone 1 (leutinizing-releasing hormone)

NCBI Summary for GNRH

The protein encoded by this gene is secreted and then cleaved to form the 10 aa luteinizing hormone-releasing hormone (LHRH, also known as gonadoliberin-1), and prolactin release-inhibiting factor (also known as GnRH-associated peptide 1). LHRH stimulates the release of luteinizing and follicle stimulating hormones, which are important for reproduction. Mutation in this gene are associated with hypogonadotropic hypogonadism. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jul 2012]
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UniProt Comments for GNRH

GNRH1: Stimulates the secretion of gonadotropins; it stimulates the secretion of both luteinizing and follicle-stimulating hormones. Belongs to the GnRH family.

Protein type: Hormone; Cell cycle regulation; Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 8p21-p11.2

Cellular Component: extracellular space; extracellular region

Molecular Function: hormone activity; luteinizing hormone-releasing factor activity

Biological Process: negative regulation of cell proliferation; response to ethanol; ovulation cycle; cell-cell signaling; regulation of gene expression; multicellular organismal development; female pregnancy; signal transduction; response to corticosteroid stimulus; negative regulation of apoptosis

Disease: Hypogonadotropic Hypogonadism 7 With Or Without Anosmia
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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