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MYF5 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS248228

MBS248228 is an antibody targeting MYF5. Also known as Rabbit Polyclonal (IgG) to Human MYF5 / MYF 5. Reactive in Human, Mouse. Host: Rabbit. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
MYF5 / MYF 5, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal (IgG) to Human MYF5 / MYF 5
Product Gene Name
anti-MYF5 antibody
Product Synonym Gene Name
MYF 5
Product Synonym Names
Anti-MYF5 / MYF 5 Antibody (aa61-110) IHC-plus; MYF5; Myf-5; Myogenic factor 5; BHLHc2; Myogenic factor myf-5; Human MYF5; MYF 5
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol
Purity/Purification
Immunoaffinity Purified
Concentration
1 mg/ml (lot specific)
Specificity
MYF5 Antibody detects endogenous levels of total MYF5 protein.
Preparation and Storage
Long term: -20 degree C; Short term: +4 degree C. Avoid repeat freeze-thaw cycles.
Molecular Weight
28,296 Da
OMIM
159990
3D Structure
ModBase 3D Structure for P13349
Target Species
Human
Immunogen Description
Synthetic peptide from human MYF5 (aa61-110).
Immunogen
MYF5 / MYF 5 antibody was raised against synthetic peptide from human MYF5 (aa61-110).
Antigen Modification
aa61-110
Applications Tested/Suitable for anti-MYF5 antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)
Application Notes for anti-MYF5 antibody
ELISA (1:40000), IHC-P (30 ug/ml), WB (1:500 - 1:1000)

Immunohistochemistry (IHC) of anti-MYF5 antibody

Human, Heart: Formalin-Fixed Paraffin-Embedded (FFPE)
Rabbit Anti-MYF5 Polyclonal Antibody – Cat# MBS248228

Western Blot (WB) of anti-MYF5 antibody

Western blot of extracts from HepG2 cells, using MYF5 Antibody. The lane on the right is treated with the synthesized peptide.
Rabbit Anti-MYF5 Polyclonal Antibody, Western Blot (WB) – Cat# MBS248228

Other Notes

Small volumes of anti-MYF5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for MYF5. It may not necessarily be applicable to this product.

NCBI GI #
156104906
NCBI GeneID
4617
NCBI Accession #
NP_005584.2
UniProt Primary Accession #
P13349
UniProt Secondary Accession #
Q6ISR9
UniProt Related Accession #
P13349
GenBank Nucleotide #
NM_005593.2
NCBI Official Full Name
myogenic factor 5
NCBI Official Synonym Full Names
myogenic factor 5
NCBI Official Symbol
MYF5
NCBI Official Synonym Symbols
bHLHc2
UniProt Protein Name
Myogenic factor 5
UniProt Synonym Protein Names
Class C basic helix-loop-helix protein 2; bHLHc2
Protein Family
Myogenic factor
UniProt Gene Name
MYF5
UniProt Synonym Gene Names
BHLHC2; Myf-5; bHLHc2
UniProt Entry Name
MYF5_HUMAN
NCBI Protein Information
myogenic factor 5; myf-5; class C basic helix-loop-helix protein 2

UniProt Comments for MYF5

Myf-5: Involved in muscle differentiation (myogenic factor). Induces fibroblasts to differentiate into myoblasts. Probable sequence specific DNA-binding protein.

Protein type: DNA-binding; Transcription factor

Chromosomal Location of Human Ortholog: 12q21

Cellular Component: nucleoplasm

Molecular Function: RNA polymerase II transcription factor activity, enhancer binding; protein binding; protein heterodimerization activity

Biological Process: transcription from RNA polymerase II promoter; muscle development; somitogenesis; skeletal muscle development; ossification; extracellular matrix organization and biogenesis; camera-type eye development; regulation of cell-matrix adhesion; muscle cell fate commitment; positive regulation of myoblast differentiation; embryonic skeletal morphogenesis; regulation of transcription from RNA polymerase II promoter; muscle cell differentiation; positive regulation of skeletal muscle fiber development; positive regulation of muscle cell differentiation; positive regulation of transcription from RNA polymerase II promoter; cartilage condensation
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Research Articles on MYF5

1. Pitx2c expression is reactivated, while expression of Myf5 is downregulated in human systolic heart failure as determined by qRT-PCR and Western blot analyses.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-MYF5 antibody

 Reference Product  PubMed Publications
 MYOG antibody  >172 publications with MYF5 and MYOG
 MYOD1 antibody  >134 publications with MYF5 and MYOD1
 MYF6 antibody  >48 publications with MYF5 and MYF6
 MEF2C antibody  >23 publications with MYF5 and MEF2C
 CTNNB1 antibody  >14 publications with MYF5 and CTNNB1
 MEF2A antibody  >9 publications with MYF5 and MEF2A
 GLI3 antibody  >3 publications with MYF5 and GLI3
 MAPK14 antibody  >1 publications with MYF5 and MAPK14

Pathways associated with anti-MYF5 antibody

 Products by Pathway  Pathway Diagram
 CDO In Myogenesis Pathway antibodies  CDO In Myogenesis Pathway Diagram
 Developmental Biology Pathway antibodies  Developmental Biology Pathway Diagram
 Id Signaling Pathway antibodies  Id Signaling Pathway Diagram
 Myogenesis Pathway antibodies  Myogenesis Pathway Diagram
 Regulation Of Wnt-mediated Beta Catenin Signaling And Target Gene Transcription Pathway antibodies  Regulation Of Wnt-mediated Beta Catenin Signaling And Target Gene Transcription Pathway Diagram
 Signaling Pathways Regulating Pluripotency Of Stem Cells antibodies  Signaling Pathways Regulating Pluripotency Of Stem Cells Diagram
 Signaling Pathways Regulating Pluripotency Of Stem Cells antibodies  Signaling Pathways Regulating Pluripotency Of Stem Cells Diagram
 MiRs In Muscle Cell Differentiation Pathway antibodies  MiRs In Muscle Cell Differentiation Pathway Diagram

Diseases associated with anti-MYF5 antibody

 Disease Name  Pubmed Publications
 Necrosis Antibodies  >14 publications with MYF5 and Necrosis
 Congenital Abnormalities Antibodies  >13 publications with MYF5 and Congenital Abnormalities
 Muscular Atrophy Antibodies  >13 publications with MYF5 and Muscular Atrophy
 Fibrosis Antibodies  >12 publications with MYF5 and Fibrosis
 Inflammation Antibodies  >12 publications with MYF5 and Inflammation
 Heart Diseases Antibodies  >7 publications with MYF5 and Heart Diseases
 Insulin Resistance Antibodies  >6 publications with MYF5 and Insulin Resistance
 Lung Diseases Antibodies  >6 publications with MYF5 and Lung Diseases
 Hyperplasia Antibodies  >5 publications with MYF5 and Hyperplasia
 Kidney Diseases Antibodies  >4 publications with MYF5 and Kidney Diseases

Organs/Tissues associated with anti-MYF5 antibody

 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >810 publications with MYF5 and Muscle
 Kidney Antibodies  >10 publications with MYF5 and Kidney
 Mouth Antibodies  >4 publications with MYF5 and Mouth
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