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C/EBP Epsilon / CEBPE (CEBPE) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS248319

MBS248319 is an antibody targeting CEBPE. Also known as Rabbit Polyclonal (IgG) to Human C/EBP Epsilon / CEBPE. Reactive in Human, Mouse, Rat. Host: Rabbit. More details

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Product Overview

Product Name
C/EBP Epsilon / CEBPE, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal (IgG) to Human C/EBP Epsilon / CEBPE
Product Gene Name
Product Synonym Names
Anti-C/EBP Epsilon / CEBPE Antibody (aa191-240) IHC-plus; CEBPE; CRP1; C/EBP epsilon; C/EBP-epsilon; Human C/EBP Epsilon; CEBPE
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol
Purity/Purification
Immunoaffinity Purified
Concentration
1 mg/ml (lot specific)
Specificity
CEBPE Antibody detects endogenous levels of total CEBPE protein.
Preparation and Storage
Store at -20 degree C for up to one year.
Molecular Weight
30,603 Da
OMIM
600749
3D Structure
ModBase 3D Structure for Q15744
Target Species
Human
Immunogen Description
Synthetic peptide from human CEBPE (aa191-240).
Immunogen
C/EBP Epsilon / CEBPE antibody was raised against synthetic peptide from human CEBPE (aa191-240).
Antigen Modification
aa191-240
Applications Tested/Suitable for anti-CEBPE antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)
Application Notes for anti-CEBPE antibody
ELISA (1:10000), IHC-P (10 ug/ml), WB (1:500 - 1:1000)

Immunohistochemistry (IHC) of anti-CEBPE antibody

Anti-C/EBP Epsilon / CEBPE antibody IHC staining of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Rabbit Anti-CEBPE Polyclonal Antibody – Cat# MBS248319

Western Blot (WB) of anti-CEBPE antibody

Western blot of extracts from NIH-3T3 cells, using CEBPE Antibody. The lane on the right is treated with the synthesized peptide.
Rabbit Anti-CEBPE Polyclonal Antibody, Western Blot (WB) – Cat# MBS248319

Other Notes

Small volumes of anti-CEBPE antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CEBPE. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
CCAAT/enhancer-binding protein epsilon
NCBI Official Synonym Full Names
CCAAT/enhancer binding protein (C/EBP), epsilon
NCBI Official Symbol
CEBPE
NCBI Official Synonym Symbols
CRP1; C/EBP-epsilon
UniProt Protein Name
CCAAT/enhancer-binding protein epsilon
UniProt Gene Name
CEBPE
UniProt Synonym Gene Names
C/EBP epsilon
UniProt Entry Name
CEBPE_HUMAN
NCBI Protein Information
CCAAT/enhancer-binding protein epsilon; c/EBP epsilon

NCBI Summary for CEBPE

The protein encoded by this gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related protein CEBP-delta. The encoded protein may be essential for terminal differentiation and functional maturation of committed granulocyte progenitor cells. Mutations in this gene have been associated with Specific Granule Deficiency, a rare congenital disorder. Multiple variants of this gene have been described, but the full-length nature of only one has been determined. [provided by RefSeq, Jul 2008]
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UniProt Comments for CEBPE

C/EBP-epsilon: C/EBP are DNA-binding proteins that recognize two different motifs: the CCAAT homology common to many promoters and the enhanced core homology common to many enhancers. Belongs to the bZIP family. C/EBP subfamily.

Protein type: Motility/polarity/chemotaxis; Transcription factor; DNA-binding

Chromosomal Location of Human Ortholog: 14q11.2

Cellular Component: nucleoplasm

Molecular Function: protein homodimerization activity; protein heterodimerization activity

Biological Process: macrophage differentiation; transcription, DNA-dependent; cytokine biosynthetic process; defense response to bacterium; defense response; positive regulation of transcription from RNA polymerase II promoter; phagocytosis

Disease: Specific Granule Deficiency
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with anti-CEBPE antibody

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