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PRKCDBP Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS248451

MBS248451 is an antibody targeting PRKCDBP. Also known as Rabbit Polyclonal (IgG) to Human PRKCDBP / CAVIN3. Reactive in Human, Mouse. Host: Rabbit. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
PRKCDBP / CAVIN3, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal (IgG) to Human PRKCDBP / CAVIN3
Product Gene Name
Product Synonym Gene Name
CAVIN3
Product Synonym Names
Anti-PRKCDBP / CAVIN3 Antibody (Internal) IHC-plus; PRKCDBP; CAVIN3; HSRBC; SRBC; Cavin-3; Human PRKCDBP; CAVIN3
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
PBS, 0.02% sodium azide.
Purity/Purification
Immunoaffinity Purified
Concentration
1 mg/ml (lot specific)
Specificity
It is predicted to not cross-react with other members of the cavin family.
Preparation and Storage
Long term: -20 degree C; Short term: +4 degree C. Avoid repeat freeze-thaw cycles.
Molecular Weight
27,701 Da
3D Structure
ModBase 3D Structure for Q969G5
Target Species
Human
Immunogen Description
17 amino acid peptide near the center of human PRKCDBP.
Immunogen
PRKCDBP / CAVIN3 antibody was raised against 17 amino acid peptide near the center of human PRKCDBP.
Antigen Modification
Internal
Applications Tested/Suitable for anti-PRKCDBP antibody
Immunohistochemistry (IHC - Paraffin), Immunofluorescence (IF), Western Blot (WB), ELISA (EIA)
Application Notes for anti-PRKCDBP antibody
ELISA, IF (20 ug/ml), IHC-P (10 ug/ml), WB (1 - 2 ug/ml)

Immunohistochemistry (IHC) of anti-PRKCDBP antibody

Anti-PRKCDBP / CAVIN3 antibody IHC staining of human lung, endothelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Rabbit Anti-PRKCDBP Polyclonal Antibody – Cat# MBS248451

Immunofluorescence (IF) of anti-PRKCDBP antibody

Immunofluorescence of PRKCDBP in human spleen tissue with PRKCDBP antibody at 20 ug/ml.
Rabbit Anti-PRKCDBP Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS248451

Western Blot (WB) of anti-PRKCDBP antibody

Western blot analysis of PRKCDBP in A20 cell lysate with PRKCDBP antibody at 1 ug/ml in (A) the absence and (B) the presence of blocking peptide.
Rabbit Anti-PRKCDBP Polyclonal Antibody, Western Blot (WB) – Cat# MBS248451

Other Notes

Small volumes of anti-PRKCDBP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for PRKCDBP. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
protein kinase C delta-binding protein
NCBI Official Synonym Full Names
protein kinase C, delta binding protein
NCBI Official Symbol
PRKCDBP
NCBI Official Synonym Symbols
SRBC; HSRBC; CAVIN3; cavin-3
UniProt Protein Name
Protein kinase C delta-binding protein
UniProt Synonym Protein Names
Cavin-3; Serum deprivation response factor-related gene product that binds to C-kinase; hSRBC
UniProt Gene Name
PRKCDBP
UniProt Synonym Gene Names
SRBC; hSRBC
UniProt Entry Name
PRDBP_HUMAN
NCBI Protein Information
protein kinase C delta-binding protein; sdr-related gene product that binds to c-kinase; serum deprivation response factor-related gene product that binds to C-kinase

NCBI Summary for PRKCDBP

The protein encoded by this gene was identified as a binding protein of the protein kinase C, delta (PRKCD). The expression of this gene in cultured cell lines is strongly induced by serum starvation. The expression of this protein was found to be down-regulated in various cancer cell lines, suggesting the possible tumor suppressor function of this protein. [provided by RefSeq, Jul 2008]
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UniProt Comments for PRKCDBP

PRKCDBP: Seems to have an immune potentiation function. Belongs to the PTRF/SDPR family.

Protein type: Tumor suppressor

Chromosomal Location of Human Ortholog: 11p15.4

Cellular Component: protein complex; cytoplasm; caveola

Molecular Function: protein binding; protein kinase C binding

Biological Process: negative regulation of protein kinase B signaling cascade; circadian regulation of gene expression; cortical actin cytoskeleton organization and biogenesis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-PRKCDBP antibody

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