Rabbit Anti-NDUFS5 Polyclonal Antibody – Cat# MBS248482

Anti-NDUFS5 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.

NDUFS5 Antibody – Rabbit Polyclonal

Name: NDUFS5 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS248482
Price: 625 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS248482

MBS248482 is an antibody targeting NDUFS5. Also known as Rabbit Polyclonal (IgG) to Human NDUFS5. Reactive in Human. Host: Rabbit. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

NDUFS5, Polyclonal Antibody

Full Product Name

Rabbit Polyclonal (IgG) to Human NDUFS5

Product Gene Name

anti-NDUFS5 antibody

Product Synonym Names

Anti-NDUFS5 Antibody IHC-plus; NDUFS5; CI-15k; Complex I-15 kDa; CI15K; CI-15 kDa; Human NDUFS5

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.

Purity/Purification

Caprylic acid and ammonium sulfate precipitation

Specificity

Human NDUFS5

Preparation and Storage

Aliquot and store at -20 degree C or -80 degree C. Avoid freeze-thaw cycles.

Molecular Weight

12,518 Da

OMIM

603847

3D Structure

ModBase 3D Structure for O43920

Target Species

Human

Immunogen Description

Recombinant human NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 protein.

Immunogen Type

Recombinant protein

Immunogen

NDUFS5 antibody was raised against recombinant human NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 protein.

Applications Tested/Suitable for anti-NDUFS5 antibody

Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)

Application Notes for anti-NDUFS5 antibody

ELISA, IHC-P (10 ug/ml), WB

Other Notes

Small volumes of anti-NDUFS5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for NDUFS5. It may not necessarily be applicable to this product.

NCBI GI #

4758790

NCBI GeneID

4725

NCBI Accession #

NP_004543.1

UniProt Primary Accession #

O43920

UniProt Related Accession #

O43920

GenBank Nucleotide #

NM_004552.2

NCBI Official Full Name

NADH dehydrogenase

NCBI Official Synonym Full Names

NADH dehydrogenase (ubiquinone) Fe-S protein 5, 15kDa (NADH-coenzyme Q reductase)

NCBI Official Symbol

NDUFS5

NCBI Official Synonym Symbols

CI15K; CI-15k

UniProt Protein Name

NADH dehydrogenase [ubiquinone] iron-sulfur protein 5

UniProt Synonym Protein Names

Complex I-15 kDa; CI-15 kDa; NADH-ubiquinone oxidoreductase 15 kDa subunit

Protein Family

NADH dehydrogenase [ubiquinone] iron-sulfur protein

UniProt Gene Name

NDUFS5

UniProt Synonym Gene Names

CI-15 kDa

UniProt Entry Name

NDUS5_HUMAN

NCBI Protein Information

NADH dehydrogenase [ubiquinone] iron-sulfur protein 5; NADH dehydrogenase [ubiquinone] iron-sulfur protein 5; CI-15 kDa; complex I-15 kDa; NADH:ubiquinone oxidoreductase 15 kDa IP subunit

NCBI Summary for NDUFS5

This gene is a member of the NADH dehydrogenase (ubiquinone) iron-sulfur protein family. The encoded protein is a subunit of the NADH:ubiquinone oxidoreductase (complex I), the first enzyme complex in the electron transport chain located in the inner mitochondrial membrane. Alternative splicing results in multiple transcript variants and pseudogenes have been identified on chromosomes 1, 4 and 17. [provided by RefSeq, May 2010]

UniProt Comments for NDUFS5

NDUFS5: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Belongs to the complex I NDUFS5 subunit family.

Protein type: Mitochondrial; Energy Metabolism - oxidative phosphorylation

Chromosomal Location of Human Ortholog: 1p34.2-p33

Cellular Component: mitochondrion; mitochondrial inner membrane; mitochondrial intermembrane space; mitochondrial respiratory chain complex I

Molecular Function: NADH dehydrogenase (ubiquinone) activity

Biological Process: cellular metabolic process; mitochondrial respiratory chain complex I assembly; mitochondrial electron transport, NADH to ubiquinone

Research Articles on NDUFS5

1. This subunit of complex I is localized in the mitochondrial inter-membrane space. The protein contains intra-molecular disulfide bridges in the twin Cx(9)C motif. Does not contain an Fe-S cluster (despite what's suggested by the name).

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-NDUFS5 antibody

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Metabolic Pathways antibodies	Metabolic Pathways Diagram
Metabolism Pathway antibodies	Metabolism Pathway Diagram
NADH Dehydrogenase (ubiquinone) Fe-S Protein/flavoprotein Complex, Mitochondria Pathway antibodies	NADH Dehydrogenase (ubiquinone) Fe-S Protein/flavoprotein Complex, Mitochondria Pathway Diagram
NADH Dehydrogenase (ubiquinone) Fe-S Protein/flavoprotein Complex, Mitochondria Pathway antibodies	NADH Dehydrogenase (ubiquinone) Fe-S Protein/flavoprotein Complex, Mitochondria Pathway Diagram
Non-alcoholic Fatty Liver Disease (NAFLD) Pathway antibodies	Non-alcoholic Fatty Liver Disease (NAFLD) Pathway Diagram

Diseases associated with anti-NDUFS5 antibody

Disease Name	Pubmed Publications
Inflammation Antibodies	>1 publications with NDUFS5 and Inflammation

Organs/Tissues associated with anti-NDUFS5 antibody

Organ/Tissue Name	Pubmed Publications
Kidney Antibodies	>1 publications with NDUFS5 and Kidney
Heart Antibodies	>1 publications with NDUFS5 and Heart
Liver Antibodies	>1 publications with NDUFS5 and Liver
Muscle Antibodies	>1 publications with NDUFS5 and Muscle