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IGSF5 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS248561

MBS248561 is an antibody targeting IGSF5. Also known as Rabbit Polyclonal to Human IGSF5 / JAM4. Reactive in Human. Host: Rabbit. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
IGSF5 / JAM4, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal to Human IGSF5 / JAM4
Product Gene Name
anti-IGSF5 antibody
Product Synonym Gene Name
JAM4
Product Synonym Names
Anti-IGSF5 / JAM4 Antibody (aa1-30) IHC-plus; IGSF5; GSF5; JAM-4; JAM4; Junctional adhesion molecule 4; Human IGSF5; JAM4
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
PBS, 0.09% sodium azide
Purity/Purification
Immunoaffinity Purified
Specificity
Human IGSF5 / JAM4
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Molecular Weight
44,593 Da
OMIM
610638
3D Structure
ModBase 3D Structure for Q9NSI5
Target Species
Human
Immunogen Description
KLH-conjugated synthetic peptide from N-terminal region of human IGSF5.
Immunogen Type
Synthetic peptide
Immunogen
IGSF5 / JAM4 antibody was raised against kLH-conjugated synthetic peptide from N-terminal region of human IGSF5.
Antigen Modification
aa1-30
Applications Tested/Suitable for anti-IGSF5 antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB)
Application Notes for anti-IGSF5 antibody
IHC-P (1:50), WB (1:1000)

Immunohistochemistry (IHC) of anti-IGSF5 antibody

Anti-IGSF5 / JAM4 antibody IHC staining of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50.
Rabbit Anti-IGSF5 Polyclonal Antibody – Cat# MBS248561

Western Blot (WB) of anti-IGSF5 antibody

IGSF5 Antibody (N-term) Western blot of 293 cell line lysates (35 ug/lane). This demonstrates the IGSF5 antibody detected the IGSF5 protein (arrow).
Rabbit Anti-IGSF5 Polyclonal Antibody, Western Blot (WB) – Cat# MBS248561

Other Notes

Small volumes of anti-IGSF5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for IGSF5. It may not necessarily be applicable to this product.

NCBI GI #
122937285
NCBI GeneID
150084
NCBI Accession #
NP_001073913.1
UniProt Primary Accession #
Q9NSI5
UniProt Related Accession #
Q9NSI5
GenBank Nucleotide #
NM_001080444.1
NCBI Official Full Name
immunoglobulin superfamily member 5
NCBI Official Synonym Full Names
immunoglobulin superfamily, member 5
NCBI Official Symbol
IGSF5
NCBI Official Synonym Symbols
GSF5; JAM4
UniProt Protein Name
Immunoglobulin superfamily member 5
UniProt Synonym Protein Names
Junctional adhesion molecule 4; JAM-4
Protein Family
Immunoglobulin superfamily
UniProt Gene Name
IGSF5
UniProt Synonym Gene Names
JAM4; IgSF5; JAM-4
UniProt Entry Name
IGSF5_HUMAN
NCBI Protein Information
immunoglobulin superfamily member 5; JAM-4; junctional adhesion molecule 4; immunoglobulin superfamily 5 like

UniProt Comments for IGSF5

IGSF5: Provides, together with MAGI1, an adhesion machinery at tight junctions, which may regulate the permeability of kidney glomerulus and small intestinal epithelial cells. Mediates calcium-independent homophilic cell adhesion. In testis, it may function as a cell adhesion molecule rather than a tight-junction protein. It may participate in the adhesion between spermatogonia- spermatogonia, spermatogonia-Sertoli cells, and Sertoli cells- Sertoli cells. Belongs to the immunoglobulin superfamily.

Protein type: Membrane protein, integral; Cell surface; Immunoglobulin superfamily; Cell adhesion

Chromosomal Location of Human Ortholog: 21q22.2

Cellular Component: neuron projection; tight junction; cell surface; cell soma; integral to membrane; plasma membrane; intercellular junction

Molecular Function: PDZ domain binding

Biological Process: cell-cell adhesion; regulation of neurogenesis
Show more

Research Articles on IGSF5

1. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-IGSF5 antibody

 Products by Pathway  Pathway Diagram
 Epithelial Cell Signaling In Helicobacter Pylori Infection Pathway antibodies  Epithelial Cell Signaling In Helicobacter Pylori Infection Pathway Diagram
 Epithelial Cell Signaling In Helicobacter Pylori Infection Pathway antibodies  Epithelial Cell Signaling In Helicobacter Pylori Infection Pathway Diagram
 Tight Junction Pathway antibodies  Tight Junction Pathway Diagram
 Tight Junction Pathway antibodies  Tight Junction Pathway Diagram

Organs/Tissues associated with anti-IGSF5 antibody

 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >3 publications with IGSF5 and Kidney
 Testis Antibodies  >1 publications with IGSF5 and Testis
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