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TLX3 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS248578

MBS248578 is an antibody targeting TLX3. Also known as Rabbit Polyclonal (IgG) to Human TLX3. Reactive in Human, Mouse, Rat. Host: Rabbit. More details

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Sample Manual Insert View PDF
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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Product Name
TLX3, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal (IgG) to Human TLX3
Product Gene Name
Product Synonym Names
Anti-TLX3 Antibody (N-Terminus) IHC-plus; TLX3; Homeobox protein Hox-11L2; HOX11L2; Homeo box 11-like 2; RNX; T-cell leukemia homeobox 3; T-cell leukemia; homeobox 3; Human TLX3
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
PBS, 0.02% sodium azide.
Purity/Purification
Immunoaffinity Purified
Concentration
1 mg/ml (lot specific)
Specificity
TLX3 antibody is predicted to not cross-react with other TLX proteins.
Preparation and Storage
Long term: -20 degree C; Short term: +4 degree C. Avoid repeat freeze-thaw cycles.
Molecular Weight
31,867 Da
OMIM
604640
3D Structure
ModBase 3D Structure for O43711
Target Species
Human
Immunogen Description
16 amino acid peptide near the amino terminus of human TLX3.
Immunogen
TLX3 antibody was raised against 16 amino acid peptide near the amino terminus of human TLX3.
Antigen Modification
N-Terminus
Applications Tested/Suitable for anti-TLX3 antibody
Immunohistochemistry (IHC - Paraffin), Immunofluorescence (IF), Western Blot (WB), ELISA (EIA)
Application Notes for anti-TLX3 antibody
ELISA, IF (20 ug/ml), IHC-P (10 ug/ml), WB (0.5 - 1 ug/ml)

Immunohistochemistry (IHC) of anti-TLX3 antibody

Anti-TLX3 antibody IHC staining of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Rabbit Anti-TLX3 Polyclonal Antibody – Cat# MBS248578

Immunofluorescence (IF) of anti-TLX3 antibody

Immunofluorescence of TLX3 in human spleen tissue with TLX3 antibody at 20 ug/ml.
Rabbit Anti-TLX3 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS248578

Western Blot (WB) of anti-TLX3 antibody

Western blot analysis of TLX3 in human spleen tissue lysate with TLX3 antibody at (A) 0.5 and (B) 1 ug/ml.
Rabbit Anti-TLX3 Polyclonal Antibody, Western Blot (WB) – Cat# MBS248578

Other Notes

Small volumes of anti-TLX3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for TLX3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
T-cell leukemia homeobox protein 3
NCBI Official Synonym Full Names
T-cell leukemia homeobox 3
NCBI Official Symbol
TLX3
NCBI Official Synonym Symbols
RNX; HOX11L2
UniProt Protein Name
T-cell leukemia homeobox protein 3
UniProt Synonym Protein Names
Homeobox protein Hox-11L2
UniProt Gene Name
TLX3
UniProt Synonym Gene Names
HOX11L2
UniProt Entry Name
TLX3_HUMAN
NCBI Protein Information
T-cell leukemia homeobox protein 3; homeo box 11-like 2; homeobox protein Hox-11L2; T-cell leukemia, homeobox 3

NCBI Summary for TLX3

RNX (HOX11L2, TLX3) belongs to a family of orphan homeobox genes that encode DNA-binding nuclear transcription factors. Members of the HOX11 gene family are characterized by a threonine-47 replacing cytosine in the highly conserved homeodomain (Dear et al., 1993 [PubMed 8099440]).[supplied by OMIM, Mar 2008]
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UniProt Comments for TLX3

TLX3:

Protein type: Cell development/differentiation; DNA-binding; Transcription factor

Chromosomal Location of Human Ortholog: 5q35.1

Cellular Component: nucleus

Molecular Function: protein binding; sequence-specific DNA binding

Biological Process: negative regulation of neuron differentiation; central nervous system development; regulation of transcription, DNA-dependent; neuron migration; neuron fate specification; neurological control of breathing; respiratory gaseous exchange
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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