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PGRMC1 Antibody – Goat Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS248603

MBS248603 is an antibody targeting PGRMC1. Also known as Goat Polyclonal to Human PGRMC1 / MPR. Reactive in Gibbon, Human, Monkey, Orangutan, Pig. Host: Goat. More details

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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Product Name
PGRMC1 / MPR, Polyclonal Antibody
Full Product Name
Goat Polyclonal to Human PGRMC1 / MPR
Product Gene Name
Product Synonym Gene Name
MPR
Product Synonym Names
Anti-PGRMC1 / MPR Antibody (C-Terminus) IHC-plus; PGRMC1; HPR6.6; Progesterone binding protein; MPR; PGRMC; Human PGRMC1; MPR
Clonality
Polyclonal
Host
Goat
Species Reactivity
Gibbon, Human, Monkey, Orangutan, Pig
Form/Format
Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Purity/Purification
Immunoaffinity Purified
Concentration
0.5 mg/ml (lot specific)
Specificity
Human PGRMC1.
Preparation and Storage
Store at -20 degree C. Minimize freezing and thawing.
Molecular Weight
15,879 Da
OMIM
300435
3D Structure
ModBase 3D Structure for O00264
Target Species
Human
Immunogen Description
Synthetic peptide C-EPKDESARKND from the C-terminus of human PGRMC1 (NP_006658.1). Percent identity by BLAST analysis: Human, Orangutan, Gibbon, Monkey, Marmoset, Pig (100%); Panda, Bovine, Bat, Horse, Rabbit (91%); Mouse, Rat, Elephant, Dog (82%).
Immunogen Type
Synthetic peptide
Immunogen
PGRMC1 / MPR antibody was raised against synthetic peptide C-EPKDESARKND from the C-terminus of human PGRMC1 (NP_006658.1). Percent identity by BLAST analysis: Human, Orangutan, Gibbon, Monkey, Marmoset, Pig (100%); Panda, Bovine, Bat, Horse, Rabbit (91%); Mouse, Rat, Elephant, Dog (82%).
Antigen Modification
C-Terminus
Applications Tested/Suitable for anti-PGRMC1 antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)
Application Notes for anti-PGRMC1 antibody
ELISA, IHC-P (5 ug/ml), WB (0.1 - 0.3 ug/ml)

Immunohistochemistry (IHC) of anti-PGRMC1 antibody

Anti-PGRMC1 / MPR antibody IHC staining of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Goat Anti-PGRMC1 Polyclonal Antibody – Cat# MBS248603

Western Blot (WB) of anti-PGRMC1 antibody

Antibody (0.1 ug/ml) staining of Human Liver lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Goat Anti-PGRMC1 Polyclonal Antibody, Western Blot (WB) – Cat# MBS248603

Other Notes

Small volumes of anti-PGRMC1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for PGRMC1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
membrane-associated progesterone receptor component 1 isoform 1
NCBI Official Synonym Full Names
progesterone receptor membrane component 1
NCBI Official Symbol
PGRMC1
NCBI Official Synonym Symbols
MPR; HPR6.6
UniProt Protein Name
Membrane-associated progesterone receptor component 1
UniProt Gene Name
PGRMC1
UniProt Synonym Gene Names
HPR6.6; PGRMC; mPR
UniProt Entry Name
PGRC1_HUMAN
NCBI Protein Information
membrane-associated progesterone receptor component 1; progesterone binding protein

NCBI Summary for PGRMC1

This gene encodes a putative membrane-associated progesterone steroid receptor. The protein is expressed predominantly in the liver and kidney. [provided by RefSeq, Mar 2010]

UniProt Comments for PGRMC1

PGRMC1: Receptor for progesterone. Widely expressed, with highest expression in liver and kidney. Belongs to the cytochrome b5 family. MAPR subfamily.

Protein type: Receptor, misc.; Membrane protein, integral

Chromosomal Location of Human Ortholog: Xq22-q24

Cellular Component: endoplasmic reticulum membrane; membrane; endoplasmic reticulum; nucleolus; integral to membrane

Molecular Function: protein binding; heme binding; steroid binding

Biological Process: axon guidance
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-PGRMC1 antibody

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