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XPNPEP2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS248614

MBS248614 is an antibody targeting XPNPEP2. Also known as Rabbit Polyclonal (IgG) to Human XPNPEP2. Reactive in Human. Host: Rabbit. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
XPNPEP2, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal (IgG) to Human XPNPEP2
Product Gene Name
Product Synonym Names
Anti-XPNPEP2 Antibody (aa198-476) IHC-plus; XPNPEP2; APP2; MAmP; Membrane-bound APP; X-prolyl aminopeptidase 2; Xaa-Pro aminopeptidase 2; X-Pro aminopeptidase 2; Membrane-bound AmP; Human XPNPEP2
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
0.1 M Tris-glycine, pH 7.0, 10% glycerol, 0.01% Thimerosal
Purity/Purification
Immunoaffinity Purified
Concentration
0.83 mg/ml (lot specific)
Specificity
Human XPNPEP2
Preparation and Storage
Keep as concentrated solution. Aliquot and store at -20 degree C or below. Avoid multiple freeze-thaw cycles.
Molecular Weight
75,625 Da
OMIM
gene 300909
3D Structure
ModBase 3D Structure for O43895
Target Species
Human
Immunogen Description
Recombinant fragment corresponding to a region within amino acids 198 and 476 of XPNPEP2 (SwissProt O43895).
Immunogen Type
Recombinant protein
Immunogen
XPNPEP2 antibody was raised against recombinant fragment corresponding to a region within amino acids 198 and 476 of XPNPEP2 (SwissProt O43895).
Antigen Modification
aa198-476
Applications Tested/Suitable for anti-XPNPEP2 antibody
Immunohistochemistry (IHC - Paraffin)
Application Notes for anti-XPNPEP2 antibody
IHC-P (7.5 ug/ml)

Immunohistochemistry (IHC) of anti-XPNPEP2 antibody

Anti-XPNPEP2 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 7.5 ug/ml.
Rabbit Anti-XPNPEP2 Polyclonal Antibody – Cat# MBS248614

Other Notes

Small volumes of anti-XPNPEP2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for XPNPEP2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
xaa-Pro aminopeptidase 2
NCBI Official Synonym Full Names
X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound
NCBI Official Symbol
XPNPEP2
NCBI Official Synonym Symbols
APP2; AEACEI
UniProt Protein Name
Xaa-Pro aminopeptidase 2
UniProt Synonym Protein Names
Aminoacylproline aminopeptidase; Membrane-bound aminopeptidase P; Membrane-bound APP; Membrane-bound AmP; mAmP; X-Pro aminopeptidase 2
UniProt Gene Name
XPNPEP2
UniProt Synonym Gene Names
Membrane-bound APP; Membrane-bound AmP; mAmP
UniProt Entry Name
XPP2_HUMAN
NCBI Protein Information
xaa-Pro aminopeptidase 2; mAmP; membrane-bound APP; membrane-bound AmP; X-Pro aminopeptidase 2; aminoacylproline aminopeptidase; membrane-bound aminopeptidase P

NCBI Summary for XPNPEP2

Aminopeptidase P is a hydrolase specific for N-terminal imido bonds, which are common to several collagen degradation products, neuropeptides, vasoactive peptides, and cytokines. Structurally, the enzyme is a member of the 'pita bread fold' family and occurs in mammalian tissues in both soluble and GPI-anchored membrane-bound forms. A membrane-bound and soluble form of this enzyme have been identified as products of two separate genes. [provided by RefSeq, Jul 2008]
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UniProt Comments for XPNPEP2

XPNPEP2: A metalloprotease that may play a role in the inflammatory process and other reactions produced in response to injury or infection. May also play a role in the metabolism of the vasodilator bradykinin. Belongs to the peptidase M24B family.

Protein type: Membrane protein, GPI anchor; Protease; EC 3.4.11.9

Chromosomal Location of Human Ortholog: Xq25

Cellular Component: membrane; plasma membrane

Molecular Function: metallopeptidase activity; metal ion binding; aminopeptidase activity

Biological Process: proteolysis

Disease: Angioedema Induced By Ace Inhibitors, Susceptibility To
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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