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ELMO3 Antibody – Goat Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS248630

MBS248630 is an antibody targeting ELMO3. Also known as Goat Polyclonal to Human ELMO3. Reactive in Gibbon, Gorilla, Horse, Human, Monkey, Pig. Host: Goat. More details

$680 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
ELMO3, Polyclonal Antibody
Full Product Name
Goat Polyclonal to Human ELMO3
Product Gene Name
Product Synonym Names
Anti-ELMO3 Antibody (C-Terminus) IHC-plus; ELMO3; Ced-12 homolog 3; ELMO-3; Engulfment and cell motility 3; CED-12; CED12; Human ELMO3
Clonality
Polyclonal
Host
Goat
Species Reactivity
Gibbon, Gorilla, Horse, Human, Monkey, Pig
Form/Format
Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Purity/Purification
Immunoaffinity Purified
Concentration
0.5 mg/ml (lot specific)
Specificity
Human ELMO3.
Preparation and Storage
Store at -20 degree C. Minimize freezing and thawing.
Molecular Weight
87,102 Da
OMIM
606422
3D Structure
ModBase 3D Structure for Q96BJ8
Target Species
Human
Immunogen Description
Synthetic peptide TNFNFCYDCSIAEP from the C-terminus of human ELMO3 (NP_078988.2). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Horse, Pig (100%); Panda (93%); Mouse, Hamster, Bat, Rabbit (86%).
Immunogen Type
Synthetic peptide
Immunogen
ELMO3 antibody was raised against synthetic peptide TNFNFCYDCSIAEP from the C-terminus of human ELMO3 (NP_078988.2). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Horse, Pig (100%); Panda (93%); Mouse, Hamster, Bat, Rabbit (86%).
Antigen Modification
C-Terminus
Applications Tested/Suitable for anti-ELMO3 antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB)
Application Notes for anti-ELMO3 antibody
IHC-P (5 ug/ml), WB (1 - 3 ug/ml)

Immunohistochemistry (IHC) of anti-ELMO3 antibody

Anti-ELMO3 antibody IHC staining of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Goat Anti-ELMO3 Polyclonal Antibody – Cat# MBS248630

Western Blot (WB) of anti-ELMO3 antibody

Antibody staining (2 ug/ml) of Human Brain lysate (RIPA buffer, 35 ug total protein per lane). Primary incubated for 1 hour. Detected by Western blot of chemiluminescence.
Goat Anti-ELMO3 Polyclonal Antibody, Western Blot (WB) – Cat# MBS248630

Other Notes

Small volumes of anti-ELMO3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for ELMO3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
engulfment and cell motility protein 3
NCBI Official Synonym Full Names
engulfment and cell motility 3
NCBI Official Symbol
ELMO3
NCBI Official Synonym Symbols
CED12; CED-12; ELMO-3
UniProt Protein Name
Engulfment and cell motility protein 3
UniProt Gene Name
ELMO3
UniProt Entry Name
ELMO3_HUMAN
NCBI Protein Information
engulfment and cell motility protein 3; ced-12 homolog 3

NCBI Summary for ELMO3

The protein encoded by this gene is similar to a C. elegans protein that functions in phagocytosis of apoptotic cells and in cell migration. Other members of this small family of engulfment and cell motility (ELMO) proteins have been shown to interact with the dedicator of cyto-kinesis 1 protein to promote phagocytosis and effect cell shape changes. [provided by RefSeq, Jul 2008]
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UniProt Comments for ELMO3

ELMO3: Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in assocation with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 16q22.1

Cellular Component: cytoskeleton; cytoplasm

Molecular Function: SH3 domain binding

Biological Process: apoptosis; phagocytosis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with anti-ELMO3 antibody

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