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GTF3C3 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS248664

MBS248664 is an antibody targeting GTF3C3. Also known as Rabbit Polyclonal (IgG) to Human GTF3C3. Reactive in Human, Mouse. Host: Rabbit. More details

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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
GTF3C3, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal (IgG) to Human GTF3C3
Product Gene Name
Product Synonym Names
Anti-GTF3C3 Antibody (aa101-150) IHC-plus; GTF3C3; TF3C-gamma; TFIIIC102; TFIIICgamma; TFIIIC 102 kDa subunit; TFiiiC2-102; Human GTF3C3
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol
Purity/Purification
Immunoaffinity Purified
Specificity
TF3C3 Antibody detects endogenous levels of total TF3C3 protein.
Preparation and Storage
Store at -20 degree C for up to one year.
Molecular Weight
47,258 Da
OMIM
604888
3D Structure
ModBase 3D Structure for Q9Y5Q9
Target Species
Human
Immunogen Description
Synthetic peptide from human TF3C3 (aa101-150).
Immunogen
GTF3C3 antibody was raised against synthetic peptide from human TF3C3 (aa101-150).
Antigen Modification
aa101-150
Applications Tested/Suitable for anti-GTF3C3 antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)
Application Notes for anti-GTF3C3 antibody
ELISA (1:1000), IHC-P (20 ug/ml), WB (1:500 - 1:1000)

Immunohistochemistry (IHC) of anti-GTF3C3 antibody

Human, Skin: Formalin-Fixed Paraffin-Embedded (FFPE)
Rabbit Anti-GTF3C3 Polyclonal Antibody – Cat# MBS248664

Western Blot (WB) of anti-GTF3C3 antibody

Western blot of extracts from 293 cells, using TF3C3 Antibody. The lane on the right is treated with the synthesized peptide.
Rabbit Anti-GTF3C3 Polyclonal Antibody, Western Blot (WB) – Cat# MBS248664

Other Notes

Small volumes of anti-GTF3C3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for GTF3C3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
general transcription factor 3C polypeptide 3 isoform 1
NCBI Official Synonym Full Names
general transcription factor IIIC, polypeptide 3, 102kDa
NCBI Official Symbol
GTF3C3
NCBI Official Synonym Symbols
TFIIIC102; TFIIICgamma; TFiiiC2-102
UniProt Protein Name
General transcription factor 3C polypeptide 3
UniProt Synonym Protein Names
Transcription factor IIIC 102 kDa subunit; TFIIIC 102 kDa subunit; TFIIIC102; Transcription factor IIIC subunit gamma; TF3C-gamma
UniProt Gene Name
GTF3C3
UniProt Synonym Gene Names
TFIIIC 102 kDa subunit; TFIIIC102; TF3C-gamma
UniProt Entry Name
TF3C3_HUMAN
NCBI Protein Information
general transcription factor 3C polypeptide 3; TF3C-gamma; TFIIIC 102 kDa subunit; transcription factor IIIC subunit gamma

NCBI Summary for GTF3C3

The protein encoded by this gene is part of the TFIIIC2 complex, which binds to the promoters of small nuclear and cytoplasmic RNA genes in order to recruit RNA polymerase III. The TFIIIC2 complex is composed of six subunits. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
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UniProt Comments for GTF3C3

GTF3C3: Involved in RNA polymerase III-mediated transcription. Integral, tightly associated component of the DNA-binding TFIIIC2 subcomplex that directly binds tRNA and virus-associated RNA promoters. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Transcription factor; DNA-binding

Chromosomal Location of Human Ortholog: 2q33.1

Cellular Component: nucleoplasm; transcription factor TFIIIC complex

Molecular Function: protein binding; DNA binding

Biological Process: transcription from RNA polymerase III promoter; transcription, DNA-dependent; 5S class rRNA transcription; gene expression; tRNA transcription from RNA polymerase III promoter
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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