Goat Anti-DEFB107A Polyclonal Antibody – Cat# MBS248690

Anti-DEFB107A antibody IHC staining of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.

DEFB107A Antibody – Goat Polyclonal

Name: DEFB107A Antibody; Polyclonal; Goat; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS248690
Price: 625 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS248690

MBS248690 is an antibody targeting DEFB107A. Also known as Goat Polyclonal to Human DEFB107A. Reactive in Chimpanzee, Human. Host: Goat. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

DEFB107A, Polyclonal Antibody

Full Product Name

Goat Polyclonal to Human DEFB107A

Product Gene Name

anti-DEFB107A antibody

Product Synonym Gene Name

DEFB107

Product Synonym Names

Anti-DEFB107A Antibody (Internal) IHC-plus; DEFB107; Beta-defensin 7; BD-7; DEFB-7; DEFB107A; Defensin; beta 107A; Defensin; beta 7; DEFB7; Beta-defensin 107; Defensin; beta 107; Human DEFB107A

Clonality

Polyclonal

Host

Goat

Species Reactivity

Chimpanzee, Human

Form/Format

Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide

Purity/Purification

Immunoaffinity Purified

Concentration

0.5 mg/ml (lot specific)

Specificity

Human DEFB107A/B.

Preparation and Storage

Store at -20 degree C. Minimize freezing and thawing.

Molecular Weight

7,846 Da

3D Structure

ModBase 3D Structure for Q8IZN7

Target Species

Human

Immunogen Description

Synthetic peptide HRALISKRMEGHCE from an internal region of human DEFB107A (NP_001032757.2; NP_001035795.1). Percent identity by BLAST analysis: Human, Chimpanzee (100%); Gorilla, Orangutan, Gibbon, Monkey (93%); Marmoset (86%).

Immunogen Type

Synthetic peptide

Immunogen

DEFB107A antibody was raised against synthetic peptide HRALISKRMEGHCE from an internal region of human DEFB107A (NP_001032757.2; NP_001035795.1). Percent identity by BLAST analysis: Human, Chimpanzee (100%); Gorilla, Orangutan, Gibbon, Monkey (93%); Marmoset (86%).

Antigen Modification

Internal

Product Categories/Family for anti-DEFB107A antibody

Family: New

Applications Tested/Suitable for anti-DEFB107A antibody

Immunohistochemistry (IHC - Paraffin), ELISA (EIA)

Application Notes for anti-DEFB107A antibody

ELISA (1:32000), IHC-P (5 ug/ml)
Usage: Peptide ELISA: antibody detection limit dilution 1:32000. Western blot: Not tested.

Other Notes

Small volumes of anti-DEFB107A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for DEFB107A. It may not necessarily be applicable to this product.

NCBI GI #

103485145

NCBI GeneID

245910

NCBI Accession #

NP_001032757.2

UniProt Primary Accession #

Q8IZN7

UniProt Secondary Accession #

Q30E75; Q8NET2; B2RPM1

UniProt Related Accession #

Q8IZN7

GenBank Nucleotide #

NM_001037668.1

NCBI Official Full Name

beta-defensin 107

NCBI Official Synonym Full Names

defensin, beta 107A

NCBI Official Symbol

DEFB107A

NCBI Official Synonym Symbols

BD-7; DEFB-7; DEFB107

UniProt Protein Name

Beta-defensin 107

UniProt Synonym Protein Names

Beta-defensin 7; BD-7; DEFB-7; Defensin, beta 107

Protein Family

Beta-defensin

UniProt Gene Name

DEFB107A

UniProt Synonym Gene Names

DEFB107; DEFB7; BD-7; DEFB-7

UniProt Entry Name

D107A_HUMAN

NCBI Protein Information

beta-defensin 107; beta-defensin 7; defensin, beta 7

NCBI Summary for DEFB107A

Defensins form a family of antimicrobial and cytotoxic peptides made by neutrophils. Defensins are short, processed peptide molecules that are classified by structure into three groups: alpha-defensins, beta-defensins and theta-defensins. All beta-defensin genes are densely clustered in four to five syntenic chromosomal regions. Chromosome 8p23 contains at least two copies of the duplicated beta-defensin cluster. This duplication results in two identical copies of defensin, beta 107, DEFB107A and DEFB107B, in tail-to-tail orientation. This gene, DEFB107A, represents the more centromeric copy. [provided by RefSeq, Oct 2014]

UniProt Comments for DEFB107A

DEFB107A: Has antibacterial activity (Potential). Belongs to the beta-defensin family.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 8p23.1

Cellular Component: extracellular region

Biological Process: defense response to bacterium

Research Articles on DEFB107A

1. Data indicate the copy number variation (CNV) of beta-defensin gene cluster for six indels between ~1 kb distal of DEFB108P and 10 kb proximal of DEFB107.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-DEFB107A antibody

Products by Pathway	Pathway Diagram
Beta Defensins Pathway antibodies	Beta Defensins Pathway Diagram
Defensins Pathway antibodies	Defensins Pathway Diagram
Immune System Pathway antibodies	Immune System Pathway Diagram
Innate Immune System Pathway antibodies	Innate Immune System Pathway Diagram