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DIMT1L Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS248698

MBS248698 is an antibody targeting DIMT1L. Also known as Rabbit Polyclonal to Human DIMT1L. Reactive in Human. Host: Rabbit. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
DIMT1L, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal to Human DIMT1L
Product Gene Name
Product Synonym Gene Name
DIMT1
Product Synonym Names
Anti-DIMT1L Antibody (aa268-298) IHC-plus; DIMT1; 18S rRNA dimethylase; DIMT1L; Dimethyladenosine transferase; HSA9761; HUSSY5; Probable 18S rRNA dimethylase; DIM1; Human DIMT1L
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
PBS, 0.09% sodium azide
Purity/Purification
Ammonium sulfate precipitation
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Molecular Weight
35,236 Da
OMIM
612499
3D Structure
ModBase 3D Structure for Q9UNQ2
Target Species
Human
Immunogen Description
KLH conjugated synthetic peptide selected from the C-terminal region of human DIMT1.
Immunogen Type
Synthetic peptide
Immunogen
DIMT1L antibody was raised against kLH conjugated synthetic peptide selected from the C-terminal region of human DIMT1.
Antigen Modification
aa268-298
Applications Tested/Suitable for anti-DIMT1L antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB)
Application Notes for anti-DIMT1L antibody
IHC-P (1:100), WB (1:1000)

Immunohistochemistry (IHC) of anti-DIMT1L antibody

Anti-DIMT1L antibody IHC staining of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
Rabbit Anti-DIMT1L Polyclonal Antibody – Cat# MBS248698

Western Blot (WB) of anti-DIMT1L antibody

Western blot of anti-DIMT1 antibody in T47D cell line lysate (35 ug/lane). DIMT1(arrow) was detected using the purified Pab (1:60 dilution).
Rabbit Anti-DIMT1L Polyclonal Antibody, Western Blot (WB) – Cat# MBS248698

Other Notes

Small volumes of anti-DIMT1L antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for DIMT1L. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
probable dimethyladenosine transferase
NCBI Official Synonym Full Names
DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae)
NCBI Official Symbol
DIMT1
NCBI Official Synonym Symbols
DIM1; DIMT1L; HUSSY5; HSA9761
UniProt Protein Name
Probable dimethyladenosine transferase
UniProt Synonym Protein Names
DIM1 dimethyladenosine transferase 1 homolog; DIM1 dimethyladenosine transferase 1-like; Probable 18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase; Probable 18S rRNA dimethylase; Probable S-adenosylmethionine-6-N',N'-adenosyl(rRNA) dimethyltransferase
UniProt Gene Name
DIMT1
UniProt Synonym Gene Names
DIMT1L
UniProt Entry Name
DIM1_HUMAN
NCBI Protein Information
probable dimethyladenosine transferase; 18S rRNA dimethylase; probable 18S rRNA dimethylase; S-adenosylmethionine-6-N',N'-adenosyl(rRNA) dimethyltransferase; 18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase; probable S-adenosylmethionine-6-N',N'-adenosyl(rRNA) dimethyltransferase; probable 18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase

UniProt Comments for DIMT1L

DIMT1: Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA in the 40S particle. Belongs to the methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.

Protein type: RNA-binding; EC 2.1.1.183; Nucleolus; Methyltransferase

Chromosomal Location of Human Ortholog: 5q12.1

Cellular Component: cytoplasm; nucleolus; nucleus

Molecular Function: rRNA (adenine-N6,N6-)-dimethyltransferase activity

Biological Process: rRNA methylation
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-DIMT1L antibody

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