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SLC36A1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS248759

MBS248759 is an antibody targeting SLC36A1. Also known as Rabbit Polyclonal to Human SLC36A1. Reactive in Human. Host: Rabbit. More details

$650 / 0.2 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
SLC36A1, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal to Human SLC36A1
Product Gene Name
anti-SLC36A1 antibody
Product Synonym Names
Anti-SLC36A1 Antibody (aa1-30) IHC-plus; SLC36A1; LYAAT-1; LYAAT1; TRAMD3; DCT1; HPAT1; PAT1; Human SLC36A1
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
PBS, 0.09% sodium azide
Purity/Purification
Immunoaffinity Purified
Specificity
Human SLC36A1
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Molecular Weight
27,278 Da
OMIM
606561
3D Structure
ModBase 3D Structure for Q7Z2H8
Target Species
Human
Immunogen Description
KLH-conjugated synthetic peptide from N-terminal region of human SLC36A1.
Immunogen Type
Synthetic peptide
Immunogen
SLC36A1 antibody was raised against kLH-conjugated synthetic peptide from N-terminal region of human SLC36A1.
Antigen Modification
aa1-30
Applications Tested/Suitable for anti-SLC36A1 antibody
Immunohistochemistry (IHC - Paraffin), Immunofluorescence (IF), Western Blot (WB), Flow Cytometry (FC/FACS)
Application Notes for anti-SLC36A1 antibody
Flo (1:10 - 1:50), IF (1:10 - 1:50), IHC-P (5 ug/ml), WB (1:1000)

Immunohistochemistry (IHC) of anti-SLC36A1 antibody

Anti-SLC36A1 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Rabbit Anti-SLC36A1 Polyclonal Antibody – Cat# MBS248759

Immunofluorescence (IF) of anti-SLC36A1 antibody

Confocal immunofluorescence of SLC36A1 Antibody (N-term)with NCI-H460 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). Actin filaments have been labeled with Alexa Fluor 555 phalloidin (red).DAPI was used to stain the cell nuclear (blue).
Rabbit Anti-SLC36A1 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS248759

Flow Cytometry (FC/FACS) of anti-SLC36A1 antibody

SLC36A1 Antibody (N-term) flow cytometry of NCI-H460 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated donkey-anti-rabbit secondary antibodies were used for the analysis.
Rabbit Anti-SLC36A1 Polyclonal Antibody, Flow Cytometry (FC/FACS) – Cat# MBS248759

Western Blot (WB) of anti-SLC36A1 antibody

SLC36A1 Antibody (N-term) western blot analysis in NCI-H460(lane 1),K562(lane 2),A549(lane 3) cell line lysates (35ug/lane). SLC36A1 protein (arrow).
Rabbit Anti-SLC36A1 Polyclonal Antibody, Western Blot (WB) – Cat# MBS248759

Other Notes

Small volumes of anti-SLC36A1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for SLC36A1. It may not necessarily be applicable to this product.

NCBI GI #
41352721
NCBI GeneID
206358
NCBI Accession #
NP_510968.2
UniProt Primary Accession #
Q7Z2H8
UniProt Secondary Accession #
Q1LZ56; Q7Z7C0; Q86YK4; Q96M74; C9JI34
UniProt Related Accession #
Q7Z2H8
GenBank Nucleotide #
NM_078483.2
NCBI Official Full Name
proton-coupled amino acid transporter 1
NCBI Official Synonym Full Names
solute carrier family 36 (proton/amino acid symporter), member 1
NCBI Official Symbol
SLC36A1
NCBI Official Synonym Symbols
Dct1; PAT1; LYAAT1; TRAMD3
UniProt Protein Name
Proton-coupled amino acid transporter 1
UniProt Synonym Protein Names
Solute carrier family 36 member 1
Protein Family
Proton-coupled amino acid transporter
UniProt Gene Name
SLC36A1
UniProt Synonym Gene Names
PAT1; Proton/amino acid transporter 1; hPAT1
UniProt Entry Name
S36A1_HUMAN
NCBI Protein Information
proton-coupled amino acid transporter 1; hPAT1; proton/amino acid transporter 1; solute carrier family 36 member 1; lysosomal amino acid transporter 1

NCBI Summary for SLC36A1

This gene encodes a member of the eukaryote-specific amino acid/auxin permease (AAAP) 1 transporter family. The encoded protein functions as a proton-dependent, small amino acid transporter. This gene is clustered with related family members on chromosome 5q33.1. [provided by RefSeq, Jul 2008]

UniProt Comments for SLC36A1

SLC36A1: Neutral amino acid/proton symporter. Has a pH-dependent electrogenic transport activity for small amino acids such as glycine, alanine and proline. Besides small apolar L-amino acids, it also recognize their D-enantiomers and selected amino acid derivatives such as gamma-aminobutyric acid. Belongs to the amino acid/polyamine transporter 2 family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, multi-pass; Membrane protein, integral; Transporter; Transporter, SLC family

Chromosomal Location of Human Ortholog: 5q33.1

Cellular Component: endoplasmic reticulum; lysosomal membrane; integral to membrane; plasma membrane

Molecular Function: glycine transmembrane transporter activity; L-proline transmembrane transporter activity; hydrogen ion transmembrane transporter activity; hydrogen:amino acid symporter activity; L-alanine transmembrane transporter activity

Biological Process: glycine transport; proton transport; amino acid transport; ion transport; transmembrane transport; L-alanine transport
Show more

Research Articles on SLC36A1

1. Sertraline is an apparent non-competitive inhibitor of PAT1-mediated transport.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-SLC36A1 antibody

 Reference Product  PubMed Publications
 SLC15A1 antibody  >9 publications with SLC36A1 and SLC15A1
 SLC6A20 antibody  >3 publications with SLC36A1 and SLC6A20

Pathways associated with anti-SLC36A1 antibody

 Products by Pathway  Pathway Diagram
 Amino Acid Transport Across The Plasma Membrane Pathway antibodies  Amino Acid Transport Across The Plasma Membrane Pathway Diagram
 Protein Digestion And Absorption Pathway antibodies  Protein Digestion And Absorption Pathway Diagram
 Protein Digestion And Absorption Pathway antibodies  Protein Digestion And Absorption Pathway Diagram
 Proton-coupled Neutral Amino Acid Transporters Pathway antibodies  Proton-coupled Neutral Amino Acid Transporters Pathway Diagram
 SLC-mediated Transmembrane Transport Pathway antibodies  SLC-mediated Transmembrane Transport Pathway Diagram
 Transmembrane Transport Of Small Molecules Pathway antibodies  Transmembrane Transport Of Small Molecules Pathway Diagram
 Transport Of Inorganic Cations/anions And Amino Acids/oligopeptides Pathway antibodies  Transport Of Inorganic Cations/anions And Amino Acids/oligopeptides Pathway Diagram

Diseases associated with anti-SLC36A1 antibody

 Disease Name  Pubmed Publications
 Brain Diseases Antibodies  >3 publications with SLC36A1 and Brain Diseases
 Liver Diseases Antibodies  >2 publications with SLC36A1 and Liver Diseases
 Disease Models, Animal Antibodies  >2 publications with SLC36A1 and Disease Models, Animal
 Infertility, Male Antibodies  >1 publications with SLC36A1 and Infertility, Male
 Inflammation Antibodies  >1 publications with SLC36A1 and Inflammation
 Kidney Diseases Antibodies  >1 publications with SLC36A1 and Kidney Diseases

Organs/Tissues associated with anti-SLC36A1 antibody

 Organ/Tissue Name  Pubmed Publications
 Intestine Antibodies  >32 publications with SLC36A1 and Intestine
 Kidney Antibodies  >10 publications with SLC36A1 and Kidney
 Brain Antibodies  >8 publications with SLC36A1 and Brain
 Muscle Antibodies  >7 publications with SLC36A1 and Muscle
 Blood Antibodies  >6 publications with SLC36A1 and Blood
 Liver Antibodies  >4 publications with SLC36A1 and Liver
 Nerve Antibodies  >3 publications with SLC36A1 and Nerve
 Bone Antibodies  >3 publications with SLC36A1 and Bone
 Testis Antibodies  >3 publications with SLC36A1 and Testis
 Prostate Antibodies  >2 publications with SLC36A1 and Prostate
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