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SPHKAP Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS248781

MBS248781 is an antibody targeting SPHKAP. Also known as Rabbit Polyclonal (IgG) to Human SPHKAP. Reactive in Human. Host: Rabbit. More details

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Technical Datasheet View PDF
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Product Overview

Product Name
SPHKAP, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal (IgG) to Human SPHKAP
Product Gene Name
Product Synonym Names
Anti-SPHKAP Antibody (C-Terminus) IHC-plus; SPHKAP; A-kinase anchor protein SPHKAP; SKIP; KIAA1678; Human SPHKAP
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
0.1 M Tris-glycine, pH 7, 10% Glycerol, 0.01% Thimerosal
Purity/Purification
Immunoaffinity Purified
Concentration
1 mg/ml (lot specific)
Specificity
Human
Preparation and Storage
Aliquot and freeze at -20 degree C. Avoid freeze-thaw cycles.
Molecular Weight
183,414 Da
OMIM
611646
3D Structure
ModBase 3D Structure for Q2M3C7
Target Species
Human
Immunogen Description
Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1359 and 1651 (Q2M3C7) of SPHKAP. Percent identity by BLAST analysis: Human (100%).
Immunogen Type
Recombinant protein
Immunogen
SPHKAP antibody was raised against recombinant protein fragment contain a sequence corresponding to a region within amino acids 1359 and 1651 (Q2M3C7) of SPHKAP. Percent identity by BLAST analysis: Human (100%).
Antigen Modification
C-Terminus

Product Categories/Family for anti-SPHKAP antibody

Applications Tested/Suitable for anti-SPHKAP antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB)
Application Notes for anti-SPHKAP antibody
IHC-P (10 ug/ml), WB
Usage: Tested in Western blot using recombinant protein, not yet tested for detection of endogenouse SPHKAP.

Immunohistochemistry (IHC) of anti-SPHKAP antibody

Anti-SPHKAP antibody IHC staining of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Rabbit Anti-SPHKAP Polyclonal Antibody – Cat# MBS248781

Other Notes

Small volumes of anti-SPHKAP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for SPHKAP. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
A-kinase anchor protein SPHKAP isoform 1
NCBI Official Synonym Full Names
SPHK1 interactor, AKAP domain containing
NCBI Official Symbol
SPHKAP
NCBI Official Synonym Symbols
SKIP
UniProt Protein Name
A-kinase anchor protein SPHKAP
UniProt Synonym Protein Names
SPHK1-interactor and AKAP domain-containing protein; Sphingosine kinase type 1-interacting protein
UniProt Gene Name
SPHKAP
UniProt Synonym Gene Names
KIAA1678; SKIP
UniProt Entry Name
SPKAP_HUMAN
NCBI Protein Information
A-kinase anchor protein SPHKAP; sphingosine kinase type 1-interacting protein; SPHK1-interactor and AKAP domain-containing protein; SPHK1 (sphingosine kinase type 1) interacting protein

UniProt Comments for SPHKAP

SPHK1IP: Anchoring protein that binds preferentially to the type I regulatory subunit of c-AMP-dependent protein kinase (PKA type I) and targets it to distinct subcellular compartments. May act as a converging factor linking cAMP and sphingosine signaling pathways. Plays a regulatory role in the modulation of SPHK1. Belongs to the AKAP110 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: 2q36

Cellular Component: mitochondrion; Z disc

Molecular Function: protein binding; protein kinase A binding
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-SPHKAP antibody

Organs/Tissues associated with anti-SPHKAP antibody

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