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FLJ12529 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS248796

MBS248796 is an antibody targeting FLJ12529. Also known as Rabbit Polyclonal (IgG) to Human FLJ12529 / CPSF7. Reactive in Gibbon, Bovine, Chimpanzee, Dog, Guinea pig, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat. Host: Rabbit. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
FLJ12529 / CPSF7, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal (IgG) to Human FLJ12529 / CPSF7
Product Gene Name
anti-FLJ12529 antibody
Product Synonym Gene Name
CPSF7
Product Synonym Names
Anti-FLJ12529 / CPSF7 Antibody (C-Terminus) IHC-plus; CPSF7; CFIm59; CPSF 59 kDa subunit; FLJ12529; Human FLJ12529; CPSF7
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Gibbon, Bovine, Chimpanzee, Dog, Guinea pig, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat
Form/Format
Lyophilized from PBS with 2% sucrose
Purity/Purification
Protein A Purified
Concentration
1 mg/ml (lot specific)
Specificity
Human CPSF7 / FLJ12529
Preparation and Storage
Long term: -20 degree C, the use of 50% glycerol is recommended if storing aliquots in -20 degree C for long term use (up to 1 year); Short term (less than one week): +4 degree C. Avoid repeat freeze-thaw cycles.
Molecular Weight
56,375 Da
3D Structure
ModBase 3D Structure for Q8N684
Target Species
Human
Resuspension Liquid Description
After adding water, will consist of PBS buffer with 2% sucrose
Immunogen Description
Synthetic peptide from C-Terminus of human CPSF7 (Q8N684, NP_079087). Percent identity by BLAST analysis: Human, Chimpanzee, Gibbon, Monkey, Galago, Marmoset, Mouse, Rat, Elephant, Panda, Dog, Bovine, Rabbit, Horse, Pig, Guinea pig (100%).
Immunogen
FLJ12529 / CPSF7 antibody was raised against synthetic peptide from C-Terminus of human CPSF7 (Q8N684, NP_079087). Percent identity by BLAST analysis: Human, Chimpanzee, Gibbon, Monkey, Galago, Marmoset, Mouse, Rat, Elephant, Panda, Dog, Bovine, Rabbit, Horse, Pig, Guinea pig (100%); Bat, Opossum, Turkey, Platypus (92%).
Antigen Modification
C-Terminus
Applications Tested/Suitable for anti-FLJ12529 antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB)
Application Notes for anti-FLJ12529 antibody
IHC-P (10 ug/ml), WB (1.25 ug/ml)

Immunohistochemistry (IHC) of anti-FLJ12529 antibody

Anti-FLJ12529 / CPSF7 antibody IHC staining of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Rabbit Anti-FLJ12529 Polyclonal Antibody – Cat# MBS248796

Western Blot (WB) of anti-FLJ12529 antibody

A: Marker, B: HepG2 Cell Lysate, Conc: 1.25ug/ml
Rabbit Anti-FLJ12529 Polyclonal Antibody, Western Blot (WB) – Cat# MBS248796

Other Notes

Small volumes of anti-FLJ12529 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for FLJ12529. It may not necessarily be applicable to this product.

NCBI GI #
217035102
NCBI GeneID
79869
NCBI Accession #
NP_079087.3
UniProt Primary Accession #
Q8N684
UniProt Secondary Accession #
Q7Z3H9; Q9H025; Q9H9V1; B3KU04; C9K0Q4
UniProt Related Accession #
Q8N684
GenBank Nucleotide #
NM_024811.3
NCBI Official Full Name
cleavage and polyadenylation specificity factor subunit 7 isoform 1
NCBI Official Synonym Full Names
cleavage and polyadenylation specific factor 7, 59kDa
NCBI Official Symbol
CPSF7
NCBI Official Synonym Symbols
CFIm59
UniProt Protein Name
Cleavage and polyadenylation specificity factor subunit 7
UniProt Synonym Protein Names
Cleavage and polyadenylation specificity factor 59 kDa subunit; CFIm59; CPSF 59 kDa subunit; Pre-mRNA cleavage factor Im 59 kDa subunit
UniProt Gene Name
CPSF7
UniProt Synonym Gene Names
CFIm59; CPSF 59 kDa subunit
UniProt Entry Name
CPSF7_HUMAN
NCBI Protein Information
cleavage and polyadenylation specificity factor subunit 7; CPSF 59 kDa subunit; cleavage factor Im complex 59 kDa subunit; pre mRNA cleavage factor I, 59 kDa subunit; pre-mRNA cleavage factor I, 59 kDa subunit; pre-mRNA cleavage factor Im 59 kDa subunit; cleavage and polyadenylation specificity factor 59 kDa subunit

UniProt Comments for FLJ12529

CPSF7: probable component of the cleavage factor Im complex (CFIm) that plays a key role in pre-mRNA 3' processing. Binds to cleavage and polyadenylation RNA substrates. Probable component of the cleavage factor Im (CFIm) complex, composed at least of NUDT21/CPSF5 and CPSF6 or CPSF7. Two alternatively-spliced isoforms have been described.

Protein type: RNA processing; RNA-binding; RNA splicing

Chromosomal Location of Human Ortholog: 11q12.2

Cellular Component: nucleoplasm; membrane; nucleus; mRNA cleavage factor complex

Molecular Function: protein binding; nucleotide binding

Biological Process: transcription from RNA polymerase II promoter; nuclear mRNA splicing, via spliceosome; RNA splicing; gene expression; mRNA 3'-end processing; termination of RNA polymerase II transcription; protein tetramerization
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Research Articles on FLJ12529

1. Data provide evidence that CFIm exists as a heterotetramer of 25-kD, 59-kD and 68-kD subunits of CFIm: CFIm25, CFIm59 and CFIm68.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-FLJ12529 antibody

 Products by Pathway  Pathway Diagram
 Cleavage Of Growing Transcript In The Termination Region Pathway antibodies  Cleavage Of Growing Transcript In The Termination Region Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 Processing Of Capped Intron-Containing Pre-mRNA Pathway antibodies  Processing Of Capped Intron-Containing Pre-mRNA Pathway Diagram
 Processing Of Capped Intronless Pre-mRNA Pathway antibodies  Processing Of Capped Intronless Pre-mRNA Pathway Diagram
 Processing Of Intronless Pre-mRNAs Pathway antibodies  Processing Of Intronless Pre-mRNAs Pathway Diagram
 RNA Polymerase II Transcription Pathway antibodies  RNA Polymerase II Transcription Pathway Diagram
 RNA Polymerase II Transcription Termination Pathway antibodies  RNA Polymerase II Transcription Termination Pathway Diagram
 MRNA 3'-end Processing Pathway antibodies  MRNA 3'-end Processing Pathway Diagram
 MRNA Splicing Pathway antibodies  MRNA Splicing Pathway Diagram
 MRNA Splicing - Major Pathway antibodies  MRNA Splicing - Major Pathway Diagram
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