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RPL23 Antibody – Goat Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS248880

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein… More details

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Product Overview

Product Name
RPL23 / L23, Polyclonal Antibody
Full Product Name
Goat Polyclonal to Human RPL23 / L23
Product Gene Name
Product Synonym Gene Name
L23
Product Synonym Names
Anti-RPL23 / L23 Antibody (C-Terminus) IHC-plus; RPL23; 60S ribosomal protein L23; 60S ribosomal protein L17; L23; Ribosomal protein L17; Ribosomal protein L23; Human RPL23; L23
Clonality
Polyclonal
Host
Goat
Species Reactivity
Bovine, Chicken, Dog, Drosophila, Xenopus, Guinea pig, Hamster, Human, Insect, Pig, Rabbit, Zebrafish
Form/Format
Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Purity/Purification
Immunoaffinity Purified
Concentration
0.5 mg/ml (lot specific)
Specificity
Human RPL23 / L23
Preparation and Storage
Store at -20 degree C. Minimize freezing and thawing.
Molecular Weight
14,865 Da
OMIM
603662
3D Structure
ModBase 3D Structure for P62829
Target Species
Human
Immunogen Description
Synthetic peptide KECADLWPRIASN from the C-terminus of human RPL23 / L23 (NP_000969.1).
Immunogen Type
Synthetic peptide
Immunogen
RPL23 / L23 antibody was raised against synthetic peptide KECADLWPRIASN from the C-terminus of human RPL23 / L23 (NP_000969.1). Percent identity by BLAST analysis: Hamster, Elephant, Panda, Dog, Cat, Bovine, Rabbit, Pig, Opossum, Guinea pig, Turkey, Zebra finch, Chicken, Platypus, Lizard, Xenopus, Trout, Seabass, Catfish, Salmon, Stickleback, Medaka, Pike, Pufferfish, Zebrafish, Drosophila, Mosquito, Nematode, Phytophthora, Bloom alga (100%).
Antigen Modification
C-Terminus
Applications Tested/Suitable for anti-RPL23 antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)
Application Notes for anti-RPL23 antibody
ELISA (1:128000), IHC-P (5 ug/ml), WB (0.1 - 0.3 ug/ml)
Usage: Peptide ELISA: antibody detection limit dilution 1:128000. Western blot: Approx 16kD band observed in lysates of Human Colorectal Cancer and of cell lines NIH3T3 and HeLa (calculated MW of 14.9kD according to NP_000969.1). Recommended concentration:...

Immunohistochemistry (IHC) of anti-RPL23 antibody

Anti-RPL23 / L23 antibody IHC staining of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Goat Anti-RPL23 Polyclonal Antibody – Cat# MBS248880

Immunohistochemistry (IHC) of anti-RPL23 antibody

Anti-RPL23 / L23 antibody IHC staining of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Goat Anti-RPL23 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS248880

Western Blot (WB) of anti-RPL23 antibody

RPL23 antibody (0.1 ug/ml) staining of Human Colorectal Cancer lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Goat Anti-RPL23 Polyclonal Antibody, Western Blot (WB) – Cat# MBS248880

Other Notes

Small volumes of anti-RPL23 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for RPL23 purchase

MBS248880 is an antibody targeting RPL23. Also known as Goat Polyclonal to Human RPL23 / L23. Reactive in Bovine, Chicken, Dog, Drosophila, Xenopus, Guinea pig, Hamster, Human, Insect, Pig, Rabbit, Zebrafish. Host: Goat.

Additional Details

NCBI/Uniprot data below describe general gene information for RPL23. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
60S ribosomal protein L23
NCBI Official Synonym Full Names
ribosomal protein L23
NCBI Official Symbol
RPL23
NCBI Official Synonym Symbols
L23; rpL17
UniProt Protein Name
60S ribosomal protein L23
UniProt Synonym Protein Names
60S ribosomal protein L17
Protein Family
UniProt Gene Name
RPL23
UniProt Entry Name
RL23_HUMAN
NCBI Protein Information
60S ribosomal protein L23; ribosomal protein L17; 60S ribosomal protein L17

NCBI Summary for RPL23

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L14P family of ribosomal proteins. It is located in the cytoplasm. This gene has been referred to as rpL17 because the encoded protein shares amino acid identity with ribosomal protein L17 from Saccharomyces cerevisiae; however, its official symbol is RPL23. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]
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UniProt Comments for RPL23

RPL23: a ribosomal protein of the L14P family. Located in the cytoplasm. Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This protein is a component of the 60S subunit.

Protein type: Translation; Ribosomal

Chromosomal Location of Human Ortholog: 17q

Cellular Component: focal adhesion; membrane; cytoplasm; nucleolus; ribosome; cytosol

Molecular Function: protein binding; structural constituent of ribosome

Biological Process: SRP-dependent cotranslational protein targeting to membrane; ribosomal protein import into nucleus; cellular protein metabolic process; translational elongation; translation; viral reproduction; translational initiation; mRNA catabolic process, nonsense-mediated decay; gene expression; viral transcription; translational termination; viral infectious cycle
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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