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Myelin Basic Protein / MBP (MBP) Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS249055

The classic group of MBP isoforms (isoform 4-isoform 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
Myelin Basic Protein / MBP, Monoclonal Antibody
Full Product Name
Mouse Monoclonal [clone 2H9] (IgG1) to Human Myelin Basic Protein / MBP
Product Gene Name
anti-MBP antibody
Product Synonym Names
Anti-Myelin Basic Protein / MBP Antibody (clone 2H9) IHC-plus; MBP; Myelin A1 protein; Myelin basic protein; Human Myelin Basic Protein; MBP
Clonality
Monoclonal
Isotype
IgG1
Clone Number
2H9
Host
Mouse
Species Reactivity
Human
Form/Format
Ascites, 0.03% sodium azide
Purity/Purification
Ascites
Specificity
Human Myelin Basic Protein / MBP
Preparation and Storage
Long term: -20 degree C; Short term: +4 degree C; Avoid freeze-thaw cycles.
Molecular Weight
17,343 Da
OMIM
159430
3D Structure
ModBase 3D Structure for P02686
Target Species
Human
Immunogen Description
Purified recombinant fragment of human MBP expressed in E Coli.
Immunogen Type
Recombinant protein
Immunogen
Myelin Basic Protein / MBP antibody was raised against purified recombinant fragment of human MBP expressed in E Coli.
Applications Tested/Suitable for anti-MBP antibody
Immunohistochemistry (IHC - Paraffin), Immunocytochemistry (ICC), Immunofluorescence (IF), Western Blot (WB), Flow Cytometry (FC/FACS), ELISA (EIA)
Application Notes for anti-MBP antibody
ELISA (1:10000), Flo (1:200 - 1:400), ICC (1:200 - 1:1000), IF (1:1000), IHC-P (1:100), WB (1:500 - 1:2000)

Immunohistochemistry (IHC) of anti-MBP antibody

Anti-Myelin Basic Protein / MBP antibody IHC staining of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
Mouse Anti-MBP Monoclonal Antibody – Cat# MBS249055

Immunohistochemistry (IHC) of anti-MBP antibody

Anti-Myelin Basic Protein / MBP antibody IHC staining of human skeletal muscle, nerve. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Mouse Anti-MBP Monoclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS249055

Immunofluorescence (IF) of anti-MBP antibody

Immunofluorescence of MSCS cells using MBP mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.
Mouse Anti-MBP Monoclonal Antibody, Immunofluorescence (IF) – Cat# MBS249055

Flow Cytometry (FC/FACS) of anti-MBP antibody

Flow cytometry of HepG2 cells using MBP mouse mAb (green) and negative control (red).
Mouse Anti-MBP Monoclonal Antibody, Flow Cytometry (FC/FACS) – Cat# MBS249055

Western Blot (WB) of anti-MBP antibody

Western blot of MBP mAb against HEK293 (1) and MBP-hIgGFc transfected HEK293 (2) cell lysate.
Mouse Anti-MBP Monoclonal Antibody, Western Blot (WB) – Cat# MBS249055

Western Blot (WB) of anti-MBP antibody

Western blot of MBP mAb against human MBP (AA: 1-197) recombinant protein. (Expected MW is 70 kDa)
Mouse Anti-MBP Monoclonal Antibody, Western Blot (WB) – Cat# MBS249055

ELISA (EIA) of anti-MBP antibody

Red: Control Antigen (100ng); Purple: Antigen (10ng); Green: Antigen (50ng); Blue: Antigen (100ng);
Mouse Anti-MBP Monoclonal Antibody, ELISA (EIA) – Cat# MBS249055

Other Notes

Small volumes of anti-MBP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MBP purchase

MBS249055 is an antibody targeting MBP. Also known as Mouse Monoclonal [clone 2H9] (IgG1) to Human Myelin Basic Protein / MBP. Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for MBP. It may not necessarily be applicable to this product.

NCBI GI #
4505123
NCBI GeneID
4155
NCBI Accession #
NP_002376.1
UniProt Primary Accession #
P02686
UniProt Secondary Accession #
Q15337; Q15338; Q15339; Q15340; A4FU54; A6NI84; A8MY86; A8MYL4; B3KY66; B7ZKS2; B7ZKS4
UniProt Related Accession #
P02686
GenBank Nucleotide #
NM_002385.2
NCBI Official Full Name
myelin basic protein isoform 2
NCBI Official Synonym Full Names
myelin basic protein
NCBI Official Symbol
MBP
UniProt Protein Name
Myelin basic protein
UniProt Synonym Protein Names
Myelin A1 protein; Myelin membrane encephalitogenic protein
Protein Family
Myelin basic protein
UniProt Gene Name
MBP
UniProt Synonym Gene Names
MBP
UniProt Entry Name
MBP_HUMAN
NCBI Protein Information
Golli-MBP; myelin basic protein; myelin A1 protein; myelin membrane encephalitogenic protein

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-MBP antibody

 Products by Pathway  Pathway Diagram
 Glial Cell Differentiation Pathway antibodies  Glial Cell Differentiation Pathway Diagram
 MAPK Cascade Pathway antibodies  MAPK Cascade Pathway Diagram
 Neural Crest Differentiation Pathway antibodies  Neural Crest Differentiation Pathway Diagram
 Spinal Cord Injury Pathway antibodies  Spinal Cord Injury Pathway Diagram

Diseases associated with anti-MBP antibody

 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >2671 publications with MBP and Nervous System Diseases
 Demyelinating Diseases Antibodies  >1965 publications with MBP and Demyelinating Diseases
 Brain Diseases Antibodies  >1719 publications with MBP and Brain Diseases
 Disease Models, Animal Antibodies  >1381 publications with MBP and Disease Models, Animal
 Encephalomyelitis, Autoimmune, Experimental Antibodies  >1183 publications with MBP and Encephalomyelitis, Autoimmune, Experimental
 Cardiovascular Diseases Antibodies  >684 publications with MBP and Cardiovascular Diseases
 Inflammation Antibodies  >486 publications with MBP and Inflammation
 Hypertension Antibodies  >410 publications with MBP and Hypertension
 Necrosis Antibodies  >258 publications with MBP and Necrosis
 Heart Diseases Antibodies  >189 publications with MBP and Heart Diseases

Organs/Tissues associated with anti-MBP antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >3613 publications with MBP and Blood
 Brain Antibodies  >1901 publications with MBP and Brain
 Nerve Antibodies  >1409 publications with MBP and Nerve
 Heart Antibodies  >683 publications with MBP and Heart
 Spinal Cord Antibodies  >671 publications with MBP and Spinal Cord
 Kidney Antibodies  >267 publications with MBP and Kidney
 Muscle Antibodies  >245 publications with MBP and Muscle
 Spleen Antibodies  >239 publications with MBP and Spleen
 Lymph Node Antibodies  >238 publications with MBP and Lymph Node
 Lymph Antibodies  >238 publications with MBP and Lymph
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