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LSM2 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS249070

MBS249070 is an antibody targeting LSM2. Also known as Mouse Monoclonal [clone AT2B2] (IgG2a,k) to Human LSM2 / SnRNP. Reactive in Human. Host: Mouse. More details

$650 / 0.05 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
LSM2 / SnRNP, Monoclonal Antibody
Full Product Name
Mouse Monoclonal [clone AT2B2] (IgG2a,k) to Human LSM2 / SnRNP
Product Gene Name
Product Synonym Gene Name
SnRNP
Product Synonym Names
Anti-LSM2 / SnRNP Antibody (clone AT2B2) IHC-plus; LSM2; G7B; Protein G7b; YBL026W; SnRNP; C6orf28; Human LSM2; SnRNP
Clonality
Monoclonal
Isotype
IgG2a,k
Clone Number
AT2B2
Host
Mouse
Species Reactivity
Human
Form/Format
PBS, pH 7.4, 0.1% sodium azide
Purity/Purification
Protein G Purified
Concentration
1 mg/ml (lot specific)
Specificity
Human LSM2 / SnRNP
Preparation and Storage
Can be stored at 4 degree C. For long term storage, aliquot and store at -20 degree C. Avoid repeated freezing and thawing cycles.
Molecular Weight
10,835 Da
OMIM
607282
3D Structure
ModBase 3D Structure for Q9Y333
Target Species
Human
Immunogen Description
Recombinant human LSm2 (1-95aa) purified from E Coli.
Immunogen Type
Recombinant protein
Immunogen
LSM2 / SnRNP antibody was raised against recombinant human LSm2 (1-95aa) purified from E Coli.
Applications Tested/Suitable for anti-LSM2 antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)
Application Notes for anti-LSM2 antibody
ELISA, IHC-P (10 ug/ml), WB (1:1000 - 1:3000)

Immunohistochemistry (IHC) of anti-LSM2 antibody

Anti-LSM2 / SnRNP antibody IHC staining of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Mouse Anti-LSM2 Monoclonal Antibody – Cat# MBS249070

Western Blot (WB) of anti-LSM2 antibody

Western Blot: The cell lysates (30 ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human LSm2 antibody (1:1,000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.
Mouse Anti-LSM2 Monoclonal Antibody, Western Blot (WB) – Cat# MBS249070

Other Notes

Small volumes of anti-LSM2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for LSM2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
U6 snRNA-associated Sm-like protein LSm2
NCBI Official Synonym Full Names
LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
NCBI Official Symbol
LSM2
NCBI Official Synonym Symbols
G7B; snRNP; C6orf28; YBL026W
UniProt Protein Name
U6 snRNA-associated Sm-like protein LSm2
UniProt Synonym Protein Names
Protein G7b; Small nuclear ribonuclear protein D homolog; snRNP core Sm-like protein Sm-x5
UniProt Gene Name
LSM2
UniProt Synonym Gene Names
C6orf28; G7B
UniProt Entry Name
LSM2_HUMAN
NCBI Protein Information
U6 snRNA-associated Sm-like protein LSm2; protein G7b; snRNP core Sm-like protein Sm-x5; small nuclear ribonuclear protein D homolog

NCBI Summary for LSM2

This gene encodes a member of the LSm family of RNA-binding proteins. LSm proteins form stable heteromers that bind specifically to the 3'-terminal oligo(U) tract of U6 snRNA and may play a role in pre-mRNA splicing by mediating U4/U6 snRNP formation. Pseudogenes of this gene are located on the short arm of chromosomes 6 and 19. [provided by RefSeq, Nov 2011]
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UniProt Comments for LSM2

LSM2: Binds specifically to the 3'-terminal U-tract of U6 snRNA. May be involved in pre-mRNA splicing. Identified in the spliceosome C complex. LSm subunits form a heteromer with a doughnut shape. Belongs to the snRNP Sm proteins family.

Protein type: Spliceosome; RNA splicing; RNA-binding

Chromosomal Location of Human Ortholog: 6p21.3

Cellular Component: nucleoplasm; cytosol

Molecular Function: protein binding; Ral GTPase binding; protein kinase binding; U6 snRNA binding

Biological Process: nuclear mRNA splicing, via spliceosome; RNA splicing; gene expression; mRNA catabolic process, deadenylation-dependent decay
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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