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JCHAIN Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS249234

JCHAIN Antibody, IGCJ Antibody, Immunoglobulin J chain Antibody, IGJ Antibody, IgJ chain Antibody, JCH Antibody Description: Serves to link two monomer units of either IgM or IgA. In the case of IgM, the J chain-joined dimer is a nucleating unit for the IgM… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
JCHAIN / Ig J Chain, Monoclonal Antibody
Full Product Name
Anti-JCHAIN / Ig J Chain Antibody (clone 3H7) IHC-plus
Product Gene Name
Product Synonym Names
Mouse Monoclonal [clone 3H7] (IgG1) to Human JCHAIN / Ig J Chain; Human JCHAIN / Ig J Chain; IGCJ; Immunoglobulin J chain; IGJ; IgJ chain; JCH
Clonality
Monoclonal
Isotype
IgG1
Clone Number
3H7
Host
Mouse
Species Reactivity
Human
Form/Format
PBS, pH 7.3, 1% BSA, 50% glycerol, 0.02% sodium azide
Purity/Purification
Protein A/G purified
Concentration
0.43 mg/ml (lot specific)
Specificity
Human IGJ
Preparation and Storage
Store at -20 degree C. Minimize freezing and thawing.
Molecular Weight
18,099 Da
OMIM
147790
3D Structure
ModBase 3D Structure for P01591
Immunogen
JCHAIN / Ig J Chain antibody was raised against full length human recombinant protein of human IGJ(NP_653247) produced in HEK293T cell.
Immunogen Description
Full length human recombinant protein of human IGJ(NP_653247) produced in HEK293T cell.
Immunogen Type
Recombinant protein
Target Species
Human
Applications Tested/Suitable for anti-JCHAIN antibody
Immunohistochemistry (IHC) Paraffin, Western Blot (WB)
Application Notes for anti-JCHAIN antibody
IHC-P (10 ug/ml)
WB (1:2000)

Immunohistochemistry (IHC) of anti-JCHAIN antibody

Anti-IGJ antibody IHC staining of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Mouse Anti-JCHAIN Monoclonal Antibody – Cat# MBS249234

Western Blot (WB) of anti-JCHAIN antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY IGJ (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-IGJ.
Mouse Anti-JCHAIN Monoclonal Antibody, Western Blot (WB) – Cat# MBS249234

Other Notes

Small volumes of anti-JCHAIN antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for JCHAIN purchase

MBS249234 is an antibody targeting JCHAIN. Also known as Anti-JCHAIN / Ig J Chain Antibody (clone 3H7) IHC-plus. Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for JCHAIN. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
NCBI Official Full Name
Immunoglobulin J chain
NCBI Official Synonym Full Names
joining chain of multimeric IgA and IgM
NCBI Official Symbol
JCHAIN
NCBI Official Synonym Symbols
IGJ; JCH; IGCJ
UniProt Protein Name
Immunoglobulin J chain
UniProt Synonym Protein Names
Joining chain of multimeric IgA and IgM
Protein Family
UniProt Gene Name
JCHAIN
UniProt Entry Name
IGJ_HUMAN
NCBI Protein Information
immunoglobulin J chain

UniProt Comments for JCHAIN

IGJ: Serves to link two monomer units of either IgM or IgA. In the case of IgM, the J chain-joined dimer is a nucleating unit for the IgM pentamer, and in the case of IgA it induces larger polymers. It also help to bind these immunoglobulins to secretory component.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 4q21

Cellular Component: extracellular region; extracellular space

Molecular Function: antigen binding; IgA binding; peptidoglycan binding; phosphatidylcholine binding; protein homodimerization activity; single-stranded DNA binding

Biological Process: adaptive immune response; antibacterial humoral response; glomerular filtration; immune response; innate immune response; positive regulation of protein oligomerization; retinal homeostasis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
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