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AVPR1A Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS249369

AVPR1A Antibody, AVPR V1a Antibody, V1a receptor Antibody, AVPR1 Antibody, V1a vasopressin receptor Antibody, Vasopressin V1a receptor Antibody, V1aR Antibody Description: Receptor for arginine vasopressin. The activity of this receptor is mediated by G… More details

$650 / 0.2 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
AVPR1A / V1a Receptor, Monoclonal Antibody
Full Product Name
Anti-AVPR1A / V1a Receptor Antibody (clone 721CT25.2.1) IHC-plus
Product Gene Name
anti-AVPR1A antibody
Product Synonym Names
Mouse Monoclonal [clone 721CT25.2.1] (IgM) to Human AVPR1A / V1a Receptor; Human AVPR1A / V1a Receptor; AVPR V1a; V1a receptor; AVPR1; V1a vasopressin receptor; Vasopressin V1a receptor; V1aR
Clonality
Monoclonal
Isotype
IgM
Clone Number
721CT25.2.1
Host
Mouse
Species Reactivity
Mouse, Human
Form/Format
PBS, 0.09% sodium azide.
Purity/Purification
Euglobulin precipitation
Concentration
2 mg/mL (lot specific)
Specificity
Human AVPR1A / V1a Receptor
Preparation and Storage
Short term 4 degree C
Long term aliquot and store at -20 degree C
Avoid freeze thaw cycles.
Molecular Weight
46,800 Da
OMIM
600821
3D Structure
ModBase 3D Structure for P37288
Immunogen
AVPR1A / V1a Receptor antibody was raised against kLH conjugated synthetic peptide selected from 353-383 region of human AVPR1A.
Immunogen Description
KLH conjugated synthetic peptide selected from 353-383 region of human AVPR1A.
Immunogen Type
Synthetic peptide
Epitope
aa353-383
Target Species
Human
Applications Tested/Suitable for anti-AVPR1A antibody
Immunohistochemistry (IHC) Paraffin, Western Blot (WB)
Application Notes for anti-AVPR1A antibody
IHC-P (1:50)
WB (1:1000)

Other Notes

Small volumes of anti-AVPR1A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for AVPR1A purchase

MBS249369 is an antibody targeting AVPR1A. Also known as Anti-AVPR1A / V1a Receptor Antibody (clone 721CT25.2.1) IHC-plus. Reactive in Mouse, Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for AVPR1A. It may not necessarily be applicable to this product.

NCBI GI #
4502331
NCBI GeneID
552
NCBI Accession #
NP_000697.1
UniProt Primary Accession #
P37288
UniProt Related Accession #
P37288
GenBank Nucleotide #
NM_000706.4
NCBI Official Full Name
vasopressin V1a receptor
NCBI Official Synonym Full Names
arginine vasopressin receptor 1A
NCBI Official Symbol
AVPR1A
NCBI Official Synonym Symbols
V1aR; AVPR1; AVPR V1a
UniProt Protein Name
Vasopressin V1a receptor
UniProt Synonym Protein Names
AVPR V1a; Antidiuretic hormone receptor 1a; Vascular/hepatic-type arginine vasopressin receptor
Protein Family
Vasopressin V1a receptor
UniProt Gene Name
AVPR1A
UniProt Synonym Gene Names
AVPR1; V1aR
UniProt Entry Name
V1AR_HUMAN
NCBI Protein Information
vasopressin V1a receptor

NCBI Summary for AVPR1A

The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1B, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor mediates cell contraction and proliferation, platelet aggregation, release of coagulation factor and glycogenolysis. [provided by RefSeq, Jul 2008]
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UniProt Comments for AVPR1A

AVPR1A: Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Has been involved in social behaviors, including affiliation and attachment. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; GPCR, family 1; Receptor, GPCR

Chromosomal Location of Human Ortholog: 12q14-q15

Cellular Component: cytoplasmic vesicle; cytosol; endosome; integral to plasma membrane; plasma membrane

Molecular Function: peptide binding; peptide hormone binding; protein binding; protein kinase C binding; V1A vasopressin receptor binding; vasopressin receptor activity

Biological Process: blood circulation; calcium-mediated signaling; cellular response to hormone stimulus; cellular response to water deprivation; elevation of cytosolic calcium ion concentration; G-protein coupled receptor protein signaling pathway; generation of precursor metabolites and energy; grooming behavior; maternal behavior; myotube differentiation; negative regulation of female receptivity; negative regulation of transmission of nerve impulse; penile erection; phospholipase C activation; positive regulation of cell growth; positive regulation of cell proliferation; positive regulation of cellular pH reduction; positive regulation of glutamate secretion; positive regulation of heart rate; positive regulation of prostaglandin biosynthetic process; positive regulation of systemic arterial blood pressure; positive regulation of vasoconstriction; regulation of systemic arterial blood pressure by vasopressin; response to corticosterone stimulus; social behavior; sperm ejaculation; telencephalon development
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Research Articles on AVPR1A

1. examined associations between polymorphisms in OXTR and AVPR1a and individual differences in emotional and cognitive empathy 367 young adults; emotional empathy was associated solely with OXTR, whereas cognitive empathy was associated solely with AVPR1a

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-AVPR1A antibody

 Reference Product  PubMed Publications
 AVP antibody  >2340 publications with AVPR1A and AVP
 OXT antibody  >77 publications with AVPR1A and OXT
 BDKRB2 antibody  >22 publications with AVPR1A and BDKRB2
 GRP antibody  >20 publications with AVPR1A and GRP
 TBXA2R antibody  >7 publications with AVPR1A and TBXA2R
 NPS antibody  >6 publications with AVPR1A and NPS
 GRK5 antibody  >4 publications with AVPR1A and GRK5
 AGT antibody  >2 publications with AVPR1A and AGT
 AGTR1 antibody  >1 publications with AVPR1A and AGTR1

Pathways associated with anti-AVPR1A antibody

 Products by Pathway  Pathway Diagram
 Calcium Signaling Pathway antibodies  Calcium Signaling Pathway Diagram
 Calcium Signaling Pathway antibodies  Calcium Signaling Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Defective AVP Causes Neurohypophyseal Diabetes Insipidus (NDI) Pathway antibodies  Defective AVP Causes Neurohypophyseal Diabetes Insipidus (NDI) Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Disorders Of Transmembrane Transporters Pathway antibodies  Disorders Of Transmembrane Transporters Pathway Diagram
 G Alpha (q) Signalling Events Pathway antibodies  G Alpha (q) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 GPCRs, Class A Rhodopsin-like Pathway antibodies  GPCRs, Class A Rhodopsin-like Pathway Diagram

Diseases associated with anti-AVPR1A antibody

 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >647 publications with AVPR1A and Cardiovascular Diseases
 Hypertension Antibodies  >504 publications with AVPR1A and Hypertension
 Kidney Diseases Antibodies  >483 publications with AVPR1A and Kidney Diseases
 Brain Diseases Antibodies  >260 publications with AVPR1A and Brain Diseases
 Disease Models, Animal Antibodies  >223 publications with AVPR1A and Disease Models, Animal
 Hypotension Antibodies  >168 publications with AVPR1A and Hypotension
 Inflammation Antibodies  >109 publications with AVPR1A and Inflammation
 Bradycardia Antibodies  >87 publications with AVPR1A and Bradycardia
 Edema Antibodies  >80 publications with AVPR1A and Edema
 Liver Diseases Antibodies  >76 publications with AVPR1A and Liver Diseases

Organs/Tissues associated with anti-AVPR1A antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >2655 publications with AVPR1A and Brain
 Kidney Antibodies  >1422 publications with AVPR1A and Kidney
 Heart Antibodies  >952 publications with AVPR1A and Heart
 Muscle Antibodies  >637 publications with AVPR1A and Muscle
 Liver Antibodies  >497 publications with AVPR1A and Liver
 Adrenal Gland Antibodies  >281 publications with AVPR1A and Adrenal Gland
 Uterus Antibodies  >213 publications with AVPR1A and Uterus
 Parathyroid Antibodies  >70 publications with AVPR1A and Parathyroid
 Ganglia Antibodies  >58 publications with AVPR1A and Ganglia
 Intestine Antibodies  >51 publications with AVPR1A and Intestine
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